Virus enters in weak membranes/cells

Virus enters our body in many ways but having an intact strong membranes, cellular structure is very important
There are many ways to have strong membranes and cellular structure. The colorful red and yellow colors in our fruits and veggies help create strong tissues and cells. An infection, inflammation and low immune system can be an opportunity for the virus to enter and multiply. Inflammation can be brought about by stress, low immune system and intake of toxic substances/foods/drugs/carcinogens.

Corroding cells are cells that are constantly bombarded by inflammatory substances such as allergens, stress hormones and other chemicals (not essential for life, non-essential food, molds, burned food, used cooking oil or hydrogenated/trans fats). A special newborn was not affected by HIV even when the mother carries HIV virus because the newborn cells are still healthy and intact. Below is a picture depicting the entry of virus and how it can attach to our cells in many ways.
The information below is from:

Graphic of Viral Entry into Animal Cells: virus attachment to cell surface (adsorption) and virus entry into cell. Picture shows translocation, pore formation, receptor mediated endocytosis using clathrin coated vesicles and membrane fusion. Some viruses can use more than one strategy. Other means are also employed. The above image is 500 pixels across, the original measures 4,000 pixels across.

1. NAKED VIRUS – TRANSLOCATION: particle crosses cell membrane intact (cf Principles of Molecular Virolgy, 3rd Edition, Alan J. Cann, Academic Press p 117)

2. NAKED VIRUS – GENOME INJECTION: virus attaches to cell surface and releases its genome which penetrates the cytoplasm via a pore that has been created in the plasma membrane. (Bacteriophages, which attack bacterial cells, also inject their genomes and may use molecular “syringes” to do so, please see our diagram of T4 phages injecting).

3. NAKED VIRUS – ENDOCYTOSIS: virus attaches to cell surface receptor molecules and sinks into a clathrin coated pit. The pit invaginates and finally closes off creating a clathrin coated vesicle (drawn as a cage like sphere) and so the contained virus particle is drawn into the cytoplasm. The clathrin molecular cage soon dissociates into component triskelions (the propeller like objects) which leave a vesicle. The resulting uncoated vesicle transports the contained virion to an endosome. At some stage thereafter, the viral components are released. The virus shown in this example is an Adenovirus.

4. ENVELOPED VIRUS – ENDOCYTOSIS & MEMBRANE FUSION: virus enters cell by receptor mediated endocytosis. The cell membrane merges (fuses) with the endosome membrane and so the virus components are released. The virus shown here is an influenza virus, please see our Influenza virus life cycle illustration.

5. ENVELOPED VIRUS – MEMBRANE FUSION: virus enters the cell when its outer membrane fuses with the plasma membrane at the cell surface. The viral contents are then spilled into the cytoplasm of the cell. This example is HIV, which is unusual in having a conical core (most viral cores tend to be more spherical). Please see our HIV illustrations.

GENERAL POINTS: This diagram is only intended as an overview. The viruses are depicted to show general principles. NAKED VIRUSES have an exposed protein capsid, whilst ENVELOPED VIRUSES are cloaked in cell membrane, added during budding from the host cell. The fates of viral proteins and viral genetic material vary with the type of virus. Some viruses release their genetic material almost immediately (see entry 2) whereas others transport it to the cell nucleus still contained in a protein vehicle (see entry 5).

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