Higher vitamin D dietary intake is associated with lower risk of Alzheimer’s Disease

The 7-yr follow-up study concluded that higher vitamin D dietary intake was associated with a lower risk of developing AD among older women.

Hypovitaminosis D is associated with cognitive decline among older adults. The relationship between vitamin D intakes and cognitive decline is not well understood. Our objective was to determine whether the dietary intake of vitamin D was an independent predictor of the onset of dementia within 7 years among women aged 75 years and older.

Women who developed AD had lower baseline vitamin D intakes than nondemented  or those who developed other dementias . There was no difference between other dementias and no dementia.

Baseline vitamin D dietary intakes were associated with the onset of AD but not with other dementias. Being in the highest quintile of vitamin D dietary intakes was associated with a lower risk of AD compared with the lower 4 quintiles combined.

The Study

Four hundred and ninety-eight community-dwelling women (mean, 79.8 ± 3.8 years) free of vitamin D supplements from the EPIDemiology of OSteoporosis Toulouse cohort study were divided into three groups according to the onset of dementia within 7 years (ie, no dementia, Alzheimer’s disease [AD], or other dementias). Baseline vitamin D dietary intakes were estimated from self-administered food frequency questionnaire. Age, body mass index, initial cognitive performance, education level, physical activity, sun exposure, disability, number of chronic diseases, hypertension, depression, use of psychoactive drugs, and baseline season were considered as potential confounders.

Annweiler C, Rolland Y, Schott AM, Blain H, Vellas B, Herrmann FR, Beauchet O.

Source

Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, 49933 Angers, France. ceannweiler@chu-angers.fr

 

Connie’s comments: Dementia is early stage Alzheimer’s disease (considered memory cells/brain tumor because of its irreversible nature).

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