Sleep, stress and cancer cells

The Human Circadian Rhythms RT² Profiler PCR Array profiles the expression of 84 key genes defining and regulating the biological clock. Synchronization, or “entrainment”, of the circadian clock occurs via light stimulus of the hypothalamic suprachiasmatic nucleus (SCN) in the brain and via hormone signaling from the SCN in peripheral tissues.

Interacting positive and negative circadian gene feedback loops at the transcriptional and post-translational level set up the circadian “oscillator” and insure tight control over transcription factors regulating expression of the appropriate genes required during circadian days or nights.

Genes regulated by circadian rhythms are involved in a diverse range of biological processes that affect physiology, metabolism, and behavior. Although the circadian rhythm target genes in its “output” pathways vary widely from tissue to tissue, the transcription factors encoded by central clock and clock-controlled genes are mostly shared across all cell types.

Sleeping disorders (such as apnea, insomnia, and desynchronosis) disrupt the timing of the circadian clock, requiring re-entrainment and causing fatigue. Continued disruption of the circadian clock is a source of bodily stress and a risk factor for cancer and cardiovascular disease.

from http://www.quiagen.com

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During sleep, our brain allows toxins to move out of the brain and the immune system to attack these toxins. So sleep more, take calcium and magnesium in the afternoon or at night. Drink decaf coffee only in the morning. Darken the room and find a comfortable bed and environment (cooler temp) to sleep. Take your worries away, meditate and pray.

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Your referral to those ages 25 and 60 who needs a tax-free retirement plan with access to funds up to $1.5M when health threats occur is much appreciated. I am hiring Marketing Executive trainee in 50 US states to start part time and then full time after training (one week). Call Connie 408-854-1883 motherhealth@gmail.com

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connie dello buono

Health educator, author and enterpreneur motherhealth@gmail.com or conniedbuono@gmail.com ; cell 408-854-1883 Helping families in the bay area by providing compassionate and live-in caregivers for homebound bay area seniors. Blogs at www.clubalthea.com Currently writing a self help and self cure ebook to help transform others in their journey to wellness, Healing within, transform inside and out. This is a compilation of topics Connie answered at quora.com and posts in this site.

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