My answer to Is there a way to tell if I have a ALDH2 enzyme deficiency without drinking alcohol?
Answer by Connie b. Dellobuono:
Do you have difficulty sleeping? Lacking in iron (inner eyelid pale), gasping for breath when climbing stairs or mountain, skin rashes, get’s sick easily/poor immune system,exercise less, eats sugar daily, have migraines, gets irritated easily, and feeling weak? What is your diet look like? Do you have family history of diabetes, heart and liver disease? Where do you live? Is there air pollution? Do you eat protein when drinking alcohol? Do you have addiction problem?
From wiki, on oxidation (related to ALDH2 enzyme deficiency):
Oxidative stress is suspected to be important inincluding (aka MND or ALS), , , , Depression, and Multiple sclerosis. Indirect evidence via monitoring biomarkers such as reactive oxygen species, and reactive nitrogen species production, antioxidant defense indicates oxidative damage may be involved in the pathogenesis of these diseases, while cumulative oxidative stress with disrupted mitochondrial respiration and mitochondrial damage are related with Alzheimer's disease, Parkinson's disease, and other neurodegenerative diseases.
Oxidative stress is thought to be linked to certain, since oxidation of in the vascular is a precursor to formation. Oxidative stress also plays a role in the due to oxygen following . This cascade includes both and . Oxidative stress has also been implicated in .
Oxidative stress also contributes to tissue injury following irradiation and, as well as in diabetes.
Oxidative stress is likely to be involved in age-related development of cancer. The reactive species produced in oxidative stress can cause direct damage to the DNA and are therefore, and it may also suppress and promote proliferation, invasiveness and .
Infection bywhich increases the production of reactive oxygen and nitrogen species in human stomach is also thought to be important in the development of .