My answer to Why do I have a serotonin and dopamine deficiency?

Answer by Connie b. Dellobuono:

According to Dr Daniel Amen, low serotonin and dopamine makes the anterior cingulate (ACG) work hard and and makes flexibility difficult. The ACG helps the brain shift gears and detect errors

Dopamine deficiency; decreased blood flow in prefrontal cortex and cerebellum, as well as basal ganglia, which helps produce dopamine.


Peripheral serotonin is produced in the digestive tract by enterochromaffin (EC) cells and also by particular types of immune cells and neurons. Hsiao and her colleagues first wanted to know if gut microbes have any effect on serotonin production in the gut and, if so, in which types of cells. They began by measuring peripheral serotonin levels in mice with normal populations of gut bacteria and also in germ-free mice that lack these resident microbes.

The researchers found that the EC cells from germ-free mice produced approximately 60 percent less serotonin than did their peers with conventional bacterial colonies. When these germ-free mice were recolonized with normal gut microbes, the serotonin levels went back up—showing that the deficit in serotonin can be reversed.

"EC cells are rich sources of serotonin in the gut. What we saw in this experiment is that they appear to depend on microbes to make serotonin—or at least a large portion of it," says Jessica Yano, first author on the paper and a research technician working with Hsiao.

Microbes Help Produce Serotonin in Gut | Caltech


I suggest a diet with probiotics, omega 3, ketogenic diet (low carbs), avoid soda/sugar/caffeine/alcohol, exercise and adequate sleep.

Why do I have a serotonin and dopamine deficiency?