Poor Adolescent Diet May Influence Brain and Behavior in Adulthood

Summary: A new study reports adolescent male mice fed with a diet lacking Omega-3 fatty acids performed worse on memory tests and showed increased anxiety during adulthood.

Source: SfN.

Adolescent male mice fed a diet lacking omega-3 fatty acids show increased anxiety-like behavior and worse performance on a memory task in adulthood, according to new research published in The Journal of Neuroscience. The study suggests adequate nutrition in adolescence is important for the refinement of the adult brain and behavior.

The structure and function of the brain continue to change throughout adolescence, at the same time that teenagers gain increasing independence and begin to make their own food choices. Since high-calorie, low-quality diets tend to be more affordable than healthy ones, teenagers may opt for foods that lack key nutrients important for brain health such as omega-3 polyunsaturated fatty acids (n-3 PUFAs), which cannot be produced by the human body and must be obtained from foods such as fish and vegetables.

Oliver Manzoni and colleagues fed mice a balanced diet until early adolescence, when some mice were switched to a diet lacking n-3 PUFAs. Mice fed the poor diet during adolescence had reduced levels of n-3 PUFA in the medial prefrontal cortex and the nucleus accumbens in adulthood compared to control mice. The low-quality diet impaired the brain’s ability to fine-tune connections between neurons in these regions.

Image shows a knife, fork and spoon.

Author: connie dello buono

Health educator, author and enterpreneur motherhealth@gmail.com or conniedbuono@gmail.com ; cell 408-854-1883 Helping families in the bay area by providing compassionate and live-in caregivers for homebound bay area seniors. Blogs at www.clubalthea.com Developing a new site, www.avatarcare.net , for early cancer detection using genetics tests, telemedicine with electronic appointment scheduling with doctors, video chat with doctors, matching care providers with health consumers and a health concierge for all to reduce chronic care cost, find cancer cure and coordinate health care using predictive medicine and participatory.

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