Danazol, sold under the brand names Danatrol, Danocrine, Danol, and Danoval among many others, is a synthetic steroid that is used primarily in the treatment of endometriosis. It was approved by the U.S. Food and Drug Administration in 1971 as the first drug in the country to specifically treat this condition. Although it is …
Jul 13, 2007 – A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Wikipedia has an article on: danazol · Wikipedia. Pronunciation. (UK) IPA: /ˈdænəzɒɫ/. Noun.danazol (uncountable). A derivative of the synthetic steroid ethisterone, a modified testosterone, formerly used to treat endometriosis. Retrieved from “https://en.wiktionary.org/w/index.php?title=danazol&oldid=44982005 …
Danazol is a derivative of the synthetic steroid ethisterone that suppresses the production of gonadotrophins and has some weak androgenic effects. Before becoming available as a generic drug,danazol was marketed as Danocrine in the United States. It was approved by the US Food and Drug Administration (FDA) as the …
May 4, 2015 – Danazol – Get up-to-date information on Danazol side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about Danazol.
danazol | C22H27NO2 | CID 28417 – structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity … from Wikipedia … Azol; Cyclomen; Danatrol; Danazant; Danazol; Danazol Ratiopharm; Danazol-ratiopharm; Danocrine; Danol; Danoval. Ladogal …
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Low-dose Danazol for the Treatment of Telomere-Related Diseases
Researchers at the National Institutes of Health (NIH) are studying if the medication danazol can be used to treat people with short telomere disease who also have bone marrow failure, liver, or lung disease.
In recent studies, danazol, at high doses, showed a positive influence on telomere length. Additional research is needed to learn more about the role of different doses of danazol on telomere disease as well as its effects on secondary diseases.
- Are 3 and older (minors must have parent/guardian consent to participate);
- Are diagnosed with a short telomere disease;
- Also have abnormalities affecting the bone marrow such as aplastic anemia or low blood counts OR lung disease OR liver disease
- Before starting danazol, you will have tests and evaluations including measurements of your telomere length.
- Depending on your secondary disease you may also have a bone marrow biopsy, lung function tests, or evaluation of your liver.
- You will then begin taking danazol either 100 mg twice a day, or 200 mg twice a day for up to a year.
- While taking danazol you will have outpatient visits to the NIH Clinical Center after 6 months, a year, and 6 months after stopping danazol.
- Your participation in this study will last about 2 years.
Study-related tests, procedures, and medications are at no-cost. Travel within the United States may be reimbursed by the study team.
Location: The NIH Clinical Center, America’s Research Hospital is located on the Metro red line (Medical Center stop) in Bethesda, Maryland.