Potassium and the brain

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PAIN IN THE POTASSIUM CHANNELS

The removal of a certain class of potassium channels from the surface of nociceptors is believed to be a key factor in inflammatory pain signaling. Using gene interference to reduce the expression of these specific potassium channels on nociceptors, researchers were able to produce hyperexcitability in nociceptors resembling that seen in inflammatory pain signaling. READ MORE…

COMPUTATIONAL NEUROSCIENCE SUGGESTS POTASSIUM CHANNELS MORE INVOLVED IN MS THAN THOUGHT

Computational models of axonal properties suggest that problems associated with MS, and other demyelinating diseases, may be due more to an imbalance between sodium channels and potassium channels that play a role in the leak current in neuronal membranes, than to the currently targeted sodium channels of most MS drugs. READ MORE…

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