When the liver is full of toxins, the nearby organs are affected and the heart is the first to show its effects. Since the lungs get the first toxins and the bowels shows the signs, we must be aware of comorbidities.



List of Diseases in Multimorbidity Indices Measuring the Association Between Multimorbidity and Different Health Outcomes

Author Diseases
Bayliss et al. (14) Angina/coronary artery disease, asthma, back pain, bronchitis, chronic/COPD, cancer (within the past 5 years), cholesterol, elevated, colon problem (diverticulitis, irritable bowel), congestive heart failure, diabetes, hard of hearing, hypertension, kidney disease, nerve condition, osteoarthritis, osteoporosis, overweight, poor circulation (peripheral vascular diseases), rheumatic disease, other, rheumatoid arthritis, stomach problem (gastritis, peptic disease), stroke, thyroid disorder, vision problem
Byles et al. (10) Angina or chest pain, arthritis, rheumatism, blood pressure, cancer, chronic allergic or sinus problems, chronic lung disease, chronic pain, depression, dermatitis or other chronic skin condition, diabetes, digestion problems, fits, faints, funny turns, forgetfulness, gall bladder trouble, hearing problems, heart attack, heart bypass, heart failure, kidney problems, liver problems, muscle weakness or spasmca, back or spinal problems, sciatica, back or spinal problems, stroke, urinary tract problems, vision problems
Charlson et al. (11) Aids, any tumor, cerebrovascular disease, chronic pulmonary disease, congestive heart failure, connective tissue disease, dementia, diabetes, diabetes with end organ damage, hemiplegia, leukemia, lymphoma, metastatic solid tumor, mild liver disease, moderate or severe renal disease, myocardial infarction, peripheral vascular disease, ulcer disease
Crabtree et al. (45) Angina, anxiety and depression, arthritis/osteoporosis, breathlessness secondary to cardiovascular cause, breathlessness/wheeze secondary to respiratory cause, cerebrovascular disease, constipation, cough/sputum secondary to COPD/asthma, diabetes, diarrhea, epilepsy, hearing problems, Parkinson’s disease, pain, peripheral vascular disease, side effects from medications, skin disease, unsteadiness, falls and syncope, upper gastrointestinal symptoms, urinary problems, visual problems, walking and mobility
Fan et al. (46) Arthritis, cancer, cardiac disease variables (angina, any heart disease, coronary artery bypass graft surgery or percutaneous trand coronary angioplasty, coronary artery disease, prior myocardial infarction), congestive heart failure, depression, diabetes, drug abuse, enlarged prostate, heartburn, hypertension, human immunodeficiency virus disease, liver disease, lung disease, osteoporosis, posttraumatic stress disorder, renal insufficiency, seizure, stroke, thyroid disease, ulcer disease
George et al. (47) Alzheimer’s disease and other dementia, asthma, Benign prostatic hypertrophy, cerebrovascular disease, cirrhosis of the liver, COPD, diabetes mellitus, epilepsy, hepatitis B, hepatitis C, human immunodeficiency virus /acquired immunodeficiency syndrome, hypertensive heart disease, ischemic heart disease, malignant neoplasms, nephritis/nephrosis, Parkinson’s disease, peptic ulcer disease, rheumatic heart disease, skin disease, tuberculosis
Glattacker et al. (48) Cancer, coronary heart disease, dementia, depression anxiety, diabetes, diseases of the liver and gall bladder, diseases of the respiratory systems, gastrointestinal diseases, hypertension, musculoskeletal diseases, myocardial infarction (in the past), neurological diseases (stroke), peripheral vascular diseases, renal diseases
Greenfield et al. (15) Cerebral vascular accident, congestive heart failure (no known ischemic heart disease), diabetes mellitus, hepatobiliary disease, gastrointestinal disease, hypertension, ischemic heart disease, malignancies (excluding basal cell carcinoma of the skin), organic heart disease, peripheral vascular disease, primary arrhythmias and conduction problems, renal disease, respiratory problems
Groll et al. (13) Anemia, angina, anxiety, arthritis, asthma, back pain, bowel disease, cancer, congestive heart failure, COPD, depression, dementia, diabetes, hearing impairment, hypertension, kidney disease, liver disease, miocardial infarction, migraine, neurologic disease, osteoporosis, peripheral vascular disease, stroke/transient ischemic attack, upper gastrointestinal disease, visual impairment
Incalzi et al. (49) Acute leukemia, acute pancreatitis, anemia (Hb < 10 mg/dl), aplastic anemia (transfusion at intervals > 20 days), aplastic anaemia (transfusion at intervals ≤ 20 days), chronic active hepatitis/cirrhosis, chronic lymphocytic leukemia (stage A-B), chronic lymphocytic leukemia (stage C), chronic myelogenous leukemia (early stage), chronic myelogenous leukemia (blast crisis), chronic obstructive pulmonary disease, chronic respiratory failure, stage 1 (hypoxemia), chronic respiratory failure, stage 2-3 (hypoxemia and hypercapnia), Chron’s disease, ulcerative colitis, collagenosis with organ damage, congestive heart failure (NYHA I-II), congestive heart failure (NYHA III-IV), decubitus ulcers, stage 3, dementia (without anorexia, akinesia, dysphagia, decubitus ulcers), dementia (with decubitus ulcer, anorexia, akinesia, dysphagia), diabetes mellitus, diabetes mellitus with organ damage, Hodgkin’s disease, stage I-II, Hodgin’s disease, stage III, hypertension, hyperthroidism, infectious endocarditis, ischemic stroke, liver steatosis, mild liver disease, meningitis and encephalitis, mild renal failure (creatinine < 2.5 mg/dl), multiple myeloma, stage I, multiple myeloma, stage III, multiple sclerosis, myasthenia gravis (early disease), neoplastic metastatic disease, non-Hodgkin lymphomas, parenchymatous brain haemorrhages, Parkinson’s disease (with decubitus ulcers, anorexia, akinesia, dysphagia), peptic ulcer disease, peripheral arterial disease, peritoneal carcinosis, previous pulmonary embolism, pulmonary thromboembolism, sepsis, severe renal failure (creatinine > 2.5 mg/dl), transient ischemic attack, tumor (localized disease)
Kaplan and Feinstein (44) Alcoholism, cardiac, cerebral or psychic, gastrointestinal, hepatic, hypertension, locomotor impairment (regardless of cause), malignancy, miscellaneous, peripheral vascular, renal, respiratory
McGee et al. (6) Coronary heart disease, cerebrovascular accident, stroke, diabetes, hypertension
Newmann et al. (16) Arthritis, cerebrovascular disease, chronic obstructive lung disease, coronary heart disease, depression (CES-D > 10), diabetes, kidney disease
Rozzini et al. (50) Anemia, heart disease (non-isch/org), musculoskeletal diseases, parkinsonism, peripheral vascular disease, renal diseases, stroke
Sangha et al. (51) Anemia or other blood disease, back pain, cancer, depression, diabetes, heart disease, high blood pressure, kidney disease, liver disease, lung disease, other medical problems, osteoarthritis, degenerative arthritis, rheumatoid arthritis, ulcer or stomach disease
Shwartz et al. (52) Acute and chronic bronchitis and asthma, acute myocardial infarction, cerebrovascular disease, coronary artery disease without acute myocardial infarction, hip and femur fracture, prostate disease, respiratory malignancy, spine and back disease
Tooth et al. (12) Alzheimer’s disease, anxiety, arthritis, asthma, bronchitis/emphysema, chest pain, diabetes, fall caused serious injuries, fall (fractures), fall (medical attention), heart disease, hypertension, low iron, other cancers, osteoporosis, skin cancers, stroke, urinary incontinence
Von Korff et al. (53) Acne, asthma, rheumatism, Asthma, rhinitis, cancer, diabetes, epilepsy, glaucoma, gout, hyperuricemia, heart disease, high cholesterol, hypertension, migraines, Parkinson’s, respiratory illness, rheumatoid arthritis, tuberculosis, ulcers