Cancer Metastasis: Building a Framework – ScienceDirect

by GP Gupta – ‎2006 – ‎Cited by 3435 – ‎Related articles

Nov 17, 2006 – Metastasis occurs when genetically unstable cancer cells adapt to a tissue … to cancer cells and the concomitant recruitment of traits in the tumor stroma … The utter inefficiency of the metastatic process implies that healthy tissues ….. requires collusion between tumor cells and multiple nontransformed cell …

The role of the cell–cell interactions in cancer progression – NCBI

by K Kamińska – ‎2015 – ‎Cited by 45 – ‎Related articles

Interaction between cancer cells and normal cells of the primary organ … themselves, but rather conscript and corrupt resident and recruited normal cell types 9.

Missing: collusion ‎| Must include: collusion

Microenvironmental regulation of tumor progression and metastasis

by DF Quail – ‎2013 – ‎Cited by 2447 – ‎Related articles

Mar 14, 2014 – Unlike tumor cells, stromal cell types within the tumor … Bidirectional communication between cells and their microenvironment is critical for both normal tissue …. M2-to-M1 switch, recruitment of natural killer (NK) cells and subsequent tumor ….. Indeed, interruption of this interaction renders metastatic cells …

Missing: collusion ‎| Must include: collusion

Role of the tumor microenvironment in tumor progression and the …

by Y Yuan – ‎2016 – ‎Cited by 38 – ‎Related articles

Mar 7, 2016 – Through reciprocal communication, cancer cells and the microenvironment act in collusion leading to … These normal cells in the tumor microenvironment mainly consist of … The tumor cells recruit cancer-associated fibroblasts (CAFs), … the extracellular matrix (ECM) and directing cell-cell interaction (10).

Conquering the Biological Politics of Cancer: Corruption, Coercion …

Jan 3, 2018 – First, cancer cells are corrupt compared with normal cells. … They recruit cells into their midst that normally repair wounds or prevent … growing in a mouse doesn’t take this collaboration into account, giving us false hope about … we need to figure out ways to address their corruption, coercion and collusion.

An evolving cancer instigates clonally unrelated neighboring cells to …

Nov 3, 2016 – colluded” by neighboring mutated cells to disseminate, and that they can even undergo de novo …. collaborate in their access to nutrients, in resistance to therapy, and in colonization in distant organs. Systemic … Direct recruitment of …. Local dispersal of normal mammary cells by growing breast tumors.

Reprogramming Cancer Cells – Johns Hopkins Medicine

pated but that is vitally important to how cancer cells behave. … The opportunity to expand our collaborations and partnerships has never been greater. Discoveries … deeper into the role of normalepigenetic controls in cell behavior. In normal ….. For that, Dr. Pardoll recruited the help ….. collusionin infant leukemia, one of.

How Do Cytotoxic Lymphocytes Kill Cancer Cells? | Clinical Cancer …

by L Martínez-Lostao – ‎2015 – ‎Cited by 106 – ‎Related articles

Nov 15, 2015 – … are able to kill susceptible tumor cells through their interaction with their respective death receptors. …. Consequently, the oligomerized death receptors recruit the adaptor … in a wide variety of cancer cells while sparing normal cells. …… Essential complicity of perforin-granzyme and FAS-L mechanisms to …

Tumor microenvironment: angiogenesis and immunology | Abcam

Custom antibody development and commercial partnerships to advance your … The tumormicroenvironment: a cellular conspiracy … must recruit non-malignant cells from within the stromal tissue, the cellular milieu in … Just as organs within the body require constant blood supply to function normally, a growing tumor also …

Reprogramming of Tumor-Associated Macrophages with … – Frontiers

by G Genard – ‎2017 – ‎Cited by 48 – ‎Related articles

Jul 14, 2017 – Complicity of Tumor-Associated Macrophages (TAMs) in Tumor Progression. More than 50% of tumor-infiltrating cells are macrophages, named TAMs (7, 8). … In healthy tissues, macrophages offer a remarkable plasticity to …. (B) Inhibition of circulating monocyte recruitment into the tumor: two main ..