Disorders of renal function
Our kidney will be over burden and cannot clean our waste products inside our body.
Increased cancer risk
Amino acid alanine, non essential from meat, is food for cancer cells.
Disorders of liver function
Precipitated progression of coronary artery disease
Our lymphatic system helps clean our blood or circulatory system. Excess protein will clog our circulatory system.
Disorders of bone and calcium homeostasis
High dietary protein intakes are known to increase urinary calcium excretion and, if maintained, will result in sustained hypercalciuria.
The quantitative aspect of the calcium-protein interaction story can be approached best as follows. As urinary calcium rises, a potential hypocalcemic stress is created, to which the parathyroid glands respond with elevated parathyroid hormone (PTH) secretion. PTH in turn acts on 3 end organs: bone, gut, and kidney. The gut effect is mediated by increased renal synthesis of 1,25-dihydroxyvitamin D, which in turn leads to improved calcium absorption. At the same time, PTH enhances bone resorption, so that some of the calciuric loss is offset from the bony reserves, rather than exclusively from the diet. It is in this way that high protein intakes, leading to incompletely offset urinary calcium loss, might produce bone loss.