Aspirin , parasites and liver cancer

A study showed that aspirin significantly inhibited the PGHS activity as well as the motility of mf and adult parasites [5]. Aspirin, a nonsteroidal anti-inflammatory drug (NSAID) used basically to decrease pain and inflammation. However, the mode of action by which aspirin kills the parasite was not known.

Data from the study show that taking aspirinon a regular basis can lower the risk of developing liver cancer, or hepatocellular carcinoma (HCC).

The scientists defined “a regular basis” as taking two or more 325-milligram tablets per week for 5 years or more.

The study’s results are promising. “Regular use of aspirin led to significantly lower risk of developing HCC, compared to infrequent or no aspirin use, and we also found that the risk declined progressively with increasing aspirin dose and duration of use,” says lead author Dr. Tracey Simon, who is a research fellow from the Massachusetts General Hospital Division of Gastroenterology in Boston.

Heavy or long-term use of some of these medicines, such as ibuprofen, naproxen, and higher dose aspirin, can cause chronic kidney disease known as chronic interstitial nephritis. … If you have decreased kidney function, painkillers called NSAIDs (see below) and higher dose aspirin are not recommended.

In August 2014 scientists published an analysis of previous aspirin studies. The study confirmed that aspirin can lower the risk of developing bowel, stomach and oesophageal cancers. It can also lower the risk of lung, prostate and breast cancersbut not as much as the other cancer types.

Aspirin Linked to Lower Brain Cancer Risk. In the study, researchers found that people who regularly took aspirin had a nearly 34 percent lower risk of a type of brain tumor called a glioma, compared with people who didn’t take aspirin regularly.

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