Methionine-restricted diet, less meat, extends lifespan

Low amounts of the essential amino acid methionine diet help form new blood vessels

According to a new study from Harvard T.H. Chan School of Public Health, methionine-restricted diet extends lifespan and health span. Past work by Mitchell and associates has demonstrated that a methionine-limited diet routine builds production of the gas, hydrogen sulfide.  Hydrogen sulfide, the gas that gives flatulence its repulsive smell, can help reduce the risk of heart attack, stroke, cancer and help stave off dementia, research suggests. When we are sick our cells create their own hydrogen sulfide which helps keep the mitochondria – our cell’s power generators – in working order. Methionine-restricted diet do NOT contains:

  • Brazil Nuts
  • Lean Beef & Lamb (Roast Beef)
  • Cheese (Parmesan)
  • Turkey & Chicken (Chicken Breast, cooked)
  • Pork (Sirloin, cooked)

This smelly molecule, hydrogen sulfide, gives rotten eggs their characteristic odor, but is also made in our cells where it functions in myriad beneficial ways. One of these is to promote the growth of new blood vessels from endothelial cells—a process known as angiogenesis.

Lack of oxygen, or hypoxia, is the best-described trigger of angiogenesis. Hypoxia happens in tissues when a vessel is blocked, or upon intense exercise when oxygen delivery is constrained. Nonetheless, methionine restriction activated angiogenesis regardless of normal oxygen delivery, recommending involvement of a pathway detecting amino acid deprivation as opposed to hypoxia.

Large amounts of methionine can be found in eggs, meat, and fish; sesame seeds, Brazil nuts, and some other plant seeds; and oat grains.

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