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Planned Parenthood rolls out new virtual care tool in 27 states 

Photo by Michael B. Thomas/Getty Images

Planned Parenthood is diving deeper into virtual care with the launch of Planned Parenthood Direct in 27 states. The new platform will let users request birth control, get a prescription for urinary tract infection treatments and request an in-person appointment at a Planned Parenthood health center.

The new technology will be available in all 50 states by the end of 2020, according to officials.

“The Planned Parenthood Direct app is helping to minimize barriers such as time, transportation, office hours and availability,” Alexis McGill Johnson, acting president and CEO, Planned Parenthood Federation of America, said during a press event this afternoon. “At Planned Parenthood we are committed to breaking down barriers and reaching people wherever they are no matter what. By leveraging technology and combining it with the trusted expert care of our providers, we are determined to continue to fill the gap of healthcare access so more people can stay healthy and reach their life goals regardless of ZIP code or income.”

The new technology was born out of two pilot programs that were rolled out in 2014 and 2015 across six states.

“We took what we learned from these pilots to launch one telehealth app — Planned Parenthood Direct,” McGill Johnson said.

This announcement comes just weeks after the organization announced that it will be withdrawing from the Title X program, a federal family planning program for low-income patients, following the Trump administration’s recent ruling prohibiting these funds to be used for abortion counseling or referrals. McGill Johnson said that Planned Parenthood serves 40% of all Title X patients. Despite this, she reaffirmed during the event that the organization will continue to deliver healthcare.

“At Planned Parenthood we will not let this administration or anyone else deter us from our mission of delivering healthcare and information to as many as possible,” she said.

WHY IT MATTERS

The organization’s leaders are pitching the new rollout as a way to expand its services to more patients. In particular, the app caters to patients living in rural and remote communities, as well as patients who traditionally have been underserved, such as low-income and minority women.

“Many of our patients have to travel long distances to get care, have difficulty to get time off of work or find childcare, work multiple jobs or have trouble getting an appointment when they need one,” Kelly Gordon, advanced practice clinician from Planned Parenthood of the Great Northwest and Hawaiian Islands, said during the press event. “This is especially true for people living in remote or rural communities and for people who have historically faced the greatest barrier to care, such as people of color and people with low income. But through telehealth we can literally meet people where they are to get them the care they need, when they need it: after work, on their lunch break and on their phone.”

THE LARGER TREND 

This is hardly the first time Planned Parenthood has dipped its toes into the digital waters. In January the organization rolled out a new chatbot, dubbed Roo, designed to help teenage girls get answers to questions about sexual health and puberty.

In 2016 it rolled out an app called Spot On that helps users track their period and manage their birth control.

Additionally, Planned Parenthood has been involved with telemedicine care. The organization conducted a study, recently published in Obstetrics & Gynecology, about using telemedicine for medication abortion, finding that it had comparable results to those accessing in-person care.

Ginger

Behavioral health startup Ginger (formerly Ginger.io) scored $35 million in Series C funding, bringing the San Francisco-based startup’s total funding to $63 million. The new infusion of cash was led by WP Global Partners with participation from City Light Capital, Nimble Ventures, LinkedIn CEO Jeff Weiner, Khosla Ventures, Kaiser Permanente Ventures and Kapor Capital.

WHAT THEY DO 

Ginger focuses on providing digital mental health services including behavior health coaching, video therapy, tele-psychiatry visits and other self-guided content. It specifically targets those dealing with anxiety and depression. The platform offers human-to-human support as well as technology-enabled insights.

The company partners with employer organizations to provide the services to their employees.

Ginger got its start as a passive monitoring company that sold its artificial intelligence technology to hospitals, but it reinvented itself in 2017 as a healthcare provider in its own right, offering a full service online and app-based mental health services.

WHAT IT’S FOR

The startup said the new money will go toward growing its data sciences and clinical services. It is planning to expand globally within the next two years.

MARKET SNAPSHOT

Mental health apps are on the rise in digital health, as is funding news for these startups. For example: Talkspace landed $50 million in May; Finnish company Meru Health scored $4.2 million in seed funding in April; and Quartet Health, which focuses on behavioral health and primary care, raked in $60 million in June.

In a Nature Digital Medicine study, researchers found 1,435 mental health apps available in the app stores. Those apps vary from meditation and mindfulness platforms to telehealth platforms with a clinician on the other end. While mental health apps are on the rise, stakeholders have been quick to point out that many lack validation. That same study found that a majority of the apps studied do not provide evidence or peer-reviewed studies to back up their products.

Ginger has gone the case study route, publishing a number of these on their websites, as well as its consumer surveys.

ON THE RECORD 

“We have significant experience investing in healthcare and believe that technology is the key to solving the global mental health crisis,” Donald Phillips, chairman and CEO of WP Global Partners, said in a statement. “As we looked to expand our portfolio, it became clear to us that there is no other company in the world that provides emotional and mental health support as quickly and effectively as Ginger does.”

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Gut microbes, depression and other health issues

Depression breakthough: Major depressive disorder linked to major diseases

Summary: Major depressive disorder has been linked to at least 22 distinct diseases, including asthma, coronary heart disease, and an increased risk of E. coli infection.

Source: University of South Australia

Major depressive disorder – referred to colloquially as the ‘black dog’ – has been identified as a genetic cause for 20 distinct diseases, providing vital information to help detect and manage high rates of physical illnesses in people diagnosed with depression.

Assessing risk factors between depression* and 925 diseases, a study from the Australian Centre for Precision Health at the University of South Australia found a causal relationship between depression and a range of respiratory, heart and digestive diseases including: asthma, coronary heart disease, high cholesterol, oesophagitis, gastroenteritis, E. coli infections, and urinary system disorders.

UniSA researcher, Anwar Mulugeta, says understanding the relationship between depression and other diseases can reduce the incidence of comorbidities – the presence of one or more additional conditions occurring with a primary condition – and improve the lives of millions of people worldwide.

“Data shows that people living with serious mental diseases, like depression, have much higher rates of physical illness than those in the general population,” Mulugeta says.

“But until now, these studies have been complicated by the possibility of other confounding factors, or even reverse causation where the physical condition is assumed to cause depression.

“This research puts the ‘chicken and egg’ conundrum to rest, showing that depression causes disease, rather than only the other way around.

“Importantly, this research signals that an individual diagnosed with depression should now also be screened for a defined set of possible comorbidities, enabling much better clinical management and significantly improved outcomes.”

Published in Molecular Psychiatry, the study is the first to use MR-PheWAS analyses to screen for a causal link between depression and a range of diseases. MR-PheWAS is a method that uses genetic data to explore causal associations between a risk factor (depression) and a range of disease outcomes. In this study, researchers assessed data from 337,536 UK Biobank participants to confirm the range of diseases affected by depression.

This study was led by Professor Elina Hyppönen, Director of the Australian Centre for Precision Health, who says appreciating the link between depression and distinct comorbidities has important implications for individuals, practitioners and policymakers.

“Today, nearly half of the population is estimated to experience a mental health condition in their lifetime,” Prof Hyppönen says.

“Understanding the connections between depression and other diseases is critical to ensure people with depression receive the support they require. The more we can look at the individual patient as a whole, the better their outcomes are likely to be.

“Our results suggest that it is important to look beyond the obvious, and that we need to screen and effectively manage depression-related comorbidities if we want to minimise the longer-term negative implications on health.

This shows a depressed looking woman

“It’s also important to focus on diet and encourage healthy lifestyles in this context. It was concerning to see that depression was associated with multiple inflammatory and even haemorrhagic gastro-intestinal complications, which may be due to side effects from medications used to treat depression, or even due to the greater occurrence of e-coli infections, both of which could be prevented.

“Through this study we provide critical evidence to help navigate the complexities of depression and its comorbidities, with the ultimate goal of delivering customer-centric treatment strategies for people suffering from this debilitating disease.”

Notes:

* Depression is a common illness with more than 300 million people affected worldwide. It is the leading cause of ill health and disability worldwide, with more than half of the costs of depression directly or indirectly related to comorbidities. The economic burden of depression in Australia is more than $9.1 billion each year.

ABOUT THIS NEUROSCIENCE RESEARCH ARTICLE

Source:
University of South Australia
Media Contacts:
Annabel Mansfield – University of South Australia
Image Source:
The image is in the public domain.

Original Research: Closed access
“Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK Biobank”. Anwar Mulugeta, Ang Zhou, Catherine King & Elina Hyppönen.
Molecular Psychiatry. doi:10.1038/s41380-019-0486-1

Abstract

Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK Biobank

Depression affects all aspects of an individual’s life but evidence relating to the causal effects on health is limited. We used information from 337,536 UK Biobank participants and performed hypothesis-free phenome-wide association analyses between major depressive disorder (MDD) genetic risk score (GRS) and 925 disease outcomes. GRS–disease outcome associations passing the multiple-testing corrected significance threshold (P < 1.9 × 10−3) were followed by Mendelian randomisation (MR) analyses to test for causality. MDD GRS was associated with 22 distinct diseases in the phenome-wide discovery stage, with the strongest signal observed for MDD diagnosis and related co-morbidities including anxiety and sleep disorders. In inverse-variance weighted MR analyses, MDD was associated with several inflammatory and haemorrhagic gastrointestinal diseases, including oesophagitis (OR 1.32, 95% CI 1.18–1.48), non-infectious gastroenteritis (OR 1.25, 95% CI 1.06–1.48), gastrointestinal haemorrhage (OR 1.26, 95% CI 1.11–1.43) and intestinal E.coli infections (OR 3.24, 95% CI 1.74–6.02). Signals were also observed for symptoms/disorders of the urinary system (OR 1.36, 95% CI 1.19–1.56), asthma (OR 1.23, 95% CI 1.06–1.44), and painful respiration (OR 1.28, 95% CI 1.14–1.44). MDD was associated with disorders of lipid metabolism (OR 1.22, 95% CI 1.12–1.34) and ischaemic heart disease (OR 1.30, 95% CI 1.15–1.47). Sensitivity analyses excluding pleiotropic variants provided consistent associations. Our study indicates a causal link between MDD and a broad range of diseases, suggesting a notable burden of co-morbidity. Early detection and management of MDD is important, and treatment strategies should be selected to also minimise the risk of related co-morbidities.

Gut microbes influence severity of intestinal parasitic infections …


https://www.sciencedaily.com › releases › 2018/03

Mar 9, 2018 – A new study indicates that the kinds of microbes living in the gut influence the severity and recurrence of parasitic worm infections in developing countries. The findings suggest that manipulating the gut’s microbial communities may protect against intestinal parasites, which …
The Parasite Ate Your Depression | Psychology Today


https://www.psychologytoday.com › blog › evolutionary-psychiatry › the-…

May 26, 2011 – Parasites and commensal organisms may be essential for our immune …. The health of the human gut microbiome has been shown to impact …
Anxiety? Depression? Is Your Gut Microbiome to Blame? | Viome


https://www.viome.com › blog › anxiety-depression-your-gut-microbiome…

Jun 12, 2018 – Your Gut Microbiome – The Missing Link In Anxiety and Depression … gut include bacteria, viruses, yeast, parasites, fungi, bacteriophages and …
Reconceptualizing major depressive disorder as an infectious disease


https://www.ncbi.nlm.nih.gov › pmc › articles › PMC4215336

by T Canli – ‎2014 – ‎Cited by 29 – ‎Related articles

Oct 21, 2014 – I suggest that major depression may result from a parasitic, bacterial, ….. Mind-altering microorganisms: the impact of the gut microbiota on …

Abstract · ‎Background · ‎Conclusions
From gut dysbiosis to altered brain function and mental illness – NCBI


https://www.ncbi.nlm.nih.gov › pmc › articles › PMC4879184

by GB Rogers – ‎2016 – ‎Cited by 241 – ‎Related articles

Apr 19, 2016 – Major depressive disorder (MDD) is typified by markers known to be influenced by the microbiome. For example, depression-associated …

Missing: parasites ‎| Must include: parasites
How parasites and bacteria could be changing the … – The Conversation


theconversation.com › how-parasites-and-bacteria-could-be-changing-the-…

Jan 25, 2017 – This parasite can’t complete its lifecycle in humans, but we can be infected … But it was recently shown that the gut microbes that break down food … anxiety or depression by administering a “healthy” microbiome, and recent …
Are the bacteria/parasites in your gut affecting your thinking …


https://www.lesswrong.com › posts › are-the-bacteria-parasites-in-your-gut…

Jun 9, 2012 – When oral antibiotics were discontinued, bacteria in the gut returned to … factor (BDNF), which has been linked, to depression and anxiety.
Could You Fight Off Worms? Depends on Your Gut Microbes : Goats …


https://www.npr.org › sections › goatsandsoda › 2018/04/07 › could-you-fig…
Apr 7, 2018 – Nearly 25 percent of people are infected with worms. New research suggests that gut microbes may be able to help in waging war against the …

Missing: depression ‎| Must include: depression
Microbiota and parasites | ari.info | ari.info


http://www.animalresearch.info › … › Medical Advances › Research in the news

Nov 13, 2018 – Changes in our gut bacteria have been implicated in several mental health disorders, such as schizophrenia and depression, but it’s unclear …
How parasites and bacteria could be changing the … – The Independent


https://www.independent.co.uk › LIFE › PULSE › Healthy Living

Jan 30, 2017 – Parasites could play a role in a range of illnesses, including dementia ….. anxiety or depression by administering a “healthy” microbiome, and …

Oral health, memory decline, and other health issues

Oral health is an essential part of psychological well-being and overall health in older adults. Poor oral health is associated with decreased quality of life, depression, hypertension, and cognitive decline. Two Rutgers studies, co-authored by Darina Petrovsky, Bei Wu, and Weiyu Mao, and published in the Journal of the American Geriatrics Society, explored the relationship between poor oral health and cognitive decline and the effects of perceived stress and social support on dry mouth among older Chinese Americans.

Researchers interviewed more than 2,700 Chinese Americans aged 60 and older and found that nearly 50 percent of study participants reported experiencing tooth symptoms, 25.5 percent reported dry mouth. In the first study, those who reported tooth symptoms experienced declines in cognition and episodic memory, often precursors to dementia. In the second study, the researchers found that stress increased symptoms of dry mouth, leading to poorer overall oral health.

“Racial and ethnic minorities are particularly vulnerable to the negative consequences of poor oral health,” said XinQi Dong, director of Rutgers University’s Institute for Health, Health Care Policy and Aging Research. “Minorities have less access to preventive dental care that is further exacerbated by language barriers and low socioeconomic status. Older Chinese Americans are at particular risk for experiencing oral health symptoms due to lack of dental insurance or not visiting a dental clinic regularly.”

According to Dong, the increasing oral health disease burdens among older Chinese immigrants point to the need for investigations of psychosocial factors due to the current emphasis on physical diseases and health behaviors in oral health.

“Efforts must be made to increase social support to alleviate stress and the resulting dry mouth issues reported by our study participants,” Dong continued. “These efforts can help preserve older adults’ health and well-being and limit cognitive decline.”

Key findings:

  • 47.8 percent of older Chinese Americans reported having teeth symptoms; participants who reported teeth symptoms at baseline experienced their global cognition and episodic memory decline
  • 18.9 percent of older Chinese Americans reported gum symptoms.
  • 15.6 percent of older Chinese Americans reported teeth and gum symptoms.
  • 25.5 percent of older Chinese Americans reported dry mouth.
  • More perceived stress was associated with higher odds of dry mouth.

“These studies demonstrate the importance of examining immigrant oral health outcomes later in life to understand the specific type of outcomes of different cultural groups,” said Dong. “The studies further serve as a call to action for policymakers to develop programs aimed at improving oral health preventative and dental care services in this high-risk population. Darina Petrovsky, first author, added, “Examining current oral health practices among older Chinese Americans is crucial for developing culturally-tailored interventions to promote oral health and ultimately mitigate cognitive decline.”

This shows a dentist

“Poor oral health is a top concern among older Chinese Americans. In our study, the prevalence rate of dry mouth is followed by diabetes and heart disease. Our findings demonstrate the importance of studying the linkage between stress and dry mouth in this vulnerable population.” said author Weiyu Mao, Assistant Professor, School of Social Work, University of Nevada, Reno.

“Support from family and friends could be protective against dry mouth symptoms in relation to stress; however, the potential overload of such support could be detrimental to oral health outcomes among older Chinese Americans.” Mao continued. “Intervention strategies need to expand beyond the common risk factors, such as health conditions and health behaviors, and account for the psychosocial determinants, including stress and social support, to better promote oral health and reduce oral health disparities in this population.”

“Our research raises critical awareness for dental and healthcare providers of the role of perceived stress in dry mouth symptoms,” added Dong. “Working collaboratively, dental, and healthcare providers can better identify oral health symptoms as risk factors of cognitive decline in this fast-growing vulnerable population. The primary focus should include promoting optimal oral health and improving the quality of life.”

ABOUT THIS NEUROSCIENCE RESEARCH ARTICLE

Source:
Rutgers
Media Contacts:
Jacquelyn Goss – Rutgers
Image Source:
The image is in the public domain.

Original Research: Open access
“Oral Health Symptoms and Cognitive Function Among US Community‐Dwelling Chinese Older Adults”. Darina V. Petrovsky PhD, RN, Bei Wu PhD, Weiyu Mao PhD, MSW, MPhil, XinQi Dong MD, MPH.
Journal of American Geriatrics Society. doi:10.1111/jgs.15748

Abstract

Oral Health Symptoms and Cognitive Function Among US Community‐Dwelling Chinese Older Adults

BACKGROUND/OBJECTIVES
Limited research is available on the relationship between oral health symptoms and cognitive function among community‐dwelling US Chinese older adults. The purpose of this study was to examine the associations between tooth/gum symptoms and changes in cognitive function.

DESIGN
Two‐wave epidemiological study.

SETTING

Population Study of Chinese Elderly in Chicago (PINE).

PARTICIPANTS
US Chinese older adults (N = 2713; mean age = 72.6 y; 58.4% women).

MEASUREMENTS
We selected self‐reported oral (tooth and gum) symptoms as independent variables. To examine changes in cognitive function (wave 2: Baseline), we chose the following three domains: episodic memory (East Boston Memory Test); executive function (Symbol Digit Modalities Test); and working memory (Digit Span Backwards). In addition, we assessed global cognitive function by constructing a composite measure.

RESULTS
At baseline, 1297 participants (47.8%) reported having teeth symptoms, and 513 participants (18.9%) reported having gum symptoms. Adjusting for sociodemographic and health‐related characteristics, participants who reported having teeth symptoms at baseline experienced their global cognition decrease by 0.07 units (estimate = −0.07; p = .003) and their episodic memory decrease by 0.07 units (estimate = −0.07; p = .026). Participants who reported having teeth symptoms at baseline experienced a faster rate of decline in global cognition for every additional year (estimate = 0.02; p = .047). However, this effect disappeared once we adjusted for all covariates (estimate = 0.02; p = .069). We found no significant relationship between baseline gum symptoms and change of cognitive function.

CONCLUSION
Having teeth symptoms was associated with a decline in cognitive function among US Chinese older adults. Developing policy measures aimed at ameliorating health and improving cognition in this high‐risk fast‐growing population in the United States would need to include oral health preventive and dental care services. J Am Geriatr Soc 67:S532–S537, 2019.

Diet’s effect on gut bacteria and Alzheimer’s

In a small pilot study, the researchers identified several distinct gut microbiome signatures – the chemicals produced by bacteria – in study participants with mild cognitive impairment (MCI) but not in their counterparts with normal cognition, and found that these bacterial signatures correlated with higher levels of markers of Alzheimer’s disease in the cerebrospinal fluid of the participants with MCI.

Through cross-group dietary intervention, the study also showed that a modified Mediterranean-ketogenic diet produced changes in the gut microbiome and its metabolites that correlated with reduced levels of Alzheimer’s markers in the members of both study groups.

The study appears in the current issue of EBioMedicine, a journal published by The Lancet.

“The relationship of the gut microbiome and diet to neurodegenerative diseases has recently received considerable attention, and this study suggests that Alzheimer’s disease is associated with specific changes in gut bacteria and that a type of ketogenic Mediterranean diet can affect the microbiome in ways that could impact the development od dementia,” said Hariom Yadav, Ph.D., assistant professor of molecular medicine at Wake Forest School of Medicine, who co-authored the study with Suzanne Craft, Ph.D., professor gerontology and geriatric medicine at the medical school and director of Wake Forest Baptist Health’s Alzheimer’s Disease Research Center.

The randomized, double-blind, single-site study involved 17 older adults, 11 with diagnosed MCI and six with normal cognition. These participants were randomly assigned to follow either the low-carbohydrate modified Mediterranean-ketogenic diet or a low-fat, higher carbohydrate diet for six weeks then, after a six-week “washout” period, to switch to the other diet. Gut microbiome, fecal short-chain fatty acids and markers of Alzheimer’s, including amyloid and tau proteins, in cerebrospinal fluid were measured before and after each dieting period.

This shows the face of an older man

The study’s limitations include the subject group’s size, which also accounts for the lack of diversity in terms of gender, ethnicity and age.

“Our findings provide important information that future interventional and clinical studies can be based on,” Yadav said. “Determining the specific role these gut microbiome signatures have in the progression of Alzheimer’s disease could lead to novel nutritional and therapeutic approaches that would be effective against the disease.”

Funding: The research was supported by grant P30 AG049638 and award R01 AG055122 from the National Institute on Aging, Department of Defense grant W81XWH-18-1-0118, National Center for Advancing Translational Sciences grant UL1 TR001420 and a grant from the Hartman Family Foundation.

ABOUT THIS NEUROSCIENCE RESEARCH ARTICLE

Source:
Wake Forest Baptist Medical Center
Media Contacts:
Marguerite Beck – Wake Forest Baptist Medical Center
Image Source:
The image is in the public domain.

Original Research: Open access
“Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer’s disease markers in subjects with mild cognitive impairment”. Ravinder Nagpal, Bryan J. Neth, Shaohua Wang, Suzanne Craft, Hariom Yadav.
EBioMedicine. doi:10.1016/j.ebiom.2019.08.032

Abstract

Modified Mediterranean-ketogenic diet modulates gut microbiome and short-chain fatty acids in association with Alzheimer’s disease markers in subjects with mild cognitive impairment

Background
Alzheimer’s disease (AD) prevalence is increasing, but its etiology remains elusive. Gut microbes can contribute to AD pathology and may help identifying novel markers and therapies against AD. Herein, we examine how the gut microbiome differs in older adults with mild cognitive impairment compared to cognitively normal counterparts, and whether and how a modified Mediterranean-ketogenic diet (MMKD) alters the gut microbiome signature in association with cerebrospinal fluid (CSF) AD biomarkers.

Methods
A randomized, double-blind, cross-over, single-center pilot study of MMKD versus American Heart Association Diet (AHAD) intervention is performed on 17 subjects (age: 64.6 ± 6.4 yr), of which 11 have mild cognitive impairment, while 6 are cognitively normal. Subjects undergo MMKD and AHAD intervention for 6-weeks separated by 6-weeks washout periods. Gut microbiome, fecal short-chain fatty acids (SCFAs), and markers of AD in CSF including amyloid β (Aβ)-40 and Aß-42, total tau, and phosphorylated tau-181 (tau-p181) are measured at before and after diet interventions.

Findings
At baseline, subjects with normal vs. impaired cognition show no notable difference in microbiome diversity but several unique microbial signatures are detected in subjects with mild cognitive impairment. Proteobacteria correlate positively with Aβ-42: Aβ-40 while fecal propionate and butyrate correlates negatively with Aβ-42 in subjects with mild cognitive impairment. Several bacteria are differently affected by the two diets with distinct patterns between cognitively normal and impaired subjects. Notably, the abundance of Enterobacteriaceae, Akkermansia, Slackia, Christensenellaceae and Erysipelotriaceae increases while that of Bifidobacterium and Lachnobacterium reduces on MMKD, while AHAD increases Mollicutes. MMKD slightly reduces fecal lactate and acetate while increasing propionate and butyrate. Conversely, AHAD increases acetate and propionate while reducing butyrate.

Interpretation
The data suggest that specific gut microbial signatures may depict the mild cognitive impairment and that the MMKD can modulate the gut microbiome and metabolites in association with improved AD biomarkers in CSF.

Hunger hormone, parasites, Alzheimer, Parkinson

One common physiological phenomenon that is involved both in infectious and in malignant processes is the reduction in appetite: disease anorexia. An increase in plasma levels of leptin with inflammation is thought to be involved in this process. However, from an evolutionary perspective, in certain cases, it would be more adaptive for an internal parasite to stimulate the appetite of the host instead of causing its suppression.

We tested whether a parasitic infection with the larvae of the helminth parasite Taenia taeniaformis affects the levels of appetite-regulating proteins, such as leptin, ghrelin and neuropeptide-Y (NPY) in wild yellow-necked mouse (Apodemus flavicollis). We found that infected mice had lower plasma levels of leptin and increased levels of NPY than the uninfected subjects. Ghrelin levels were not associated with the occurrence of the parasites; however, these levels strongly correlated with the levels of NPY. This study suggests a possible manipulation by parasitic larvae of appetite regulation in infected subjects.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440990/

Scientists at The University of Texas at Dallas have found evidence suggesting that resistance to the “hunger hormone” ghrelin in the brain is linked to the cognitive impairments and memory loss associated with Alzheimer’s disease (AD).

The findings, based on observations of postmortem brain-tissue samples from Alzheimer’s patients and on experiments with a mouse model of AD, also suggest a possible treatment strategy for the incurable neurodegenerative disorder that affects about 5.8 million older adults in the United States.

The research was published Aug. 14 as the cover article in the journal Science Translational Medicine.

“This is a proof-of-concept study, but we are very encouraged by the results,” said Dr. Heng Du, associate professor of biological sciences at UT Dallas and corresponding author of the study.

Produced in the stomach, ghrelin sends signals to the brain that regulate energy balance and body weight. Often called the hunger hormone, it plays a role in appetite and meal initiation. But ghrelin also has been implicated in learning and memory.

The hippocampus region of the brain — crucial to learning, memory and emotions — is one of the first to suffer cell death and damage in Alzheimer’s disease due to a toxic buildup of protein fragments called amyloid beta.

In a healthy hippocampus, ghrelin binds with proteins called ghrelin receptors, which combine with similarly activated receptors for the neurotransmitter dopamine. The two receptors then form a protein complex that helps maintain communication between brain cells and, ultimately, memory.

In the new study, Du and his colleagues found that amyloid beta binds to ghrelin receptors in the hippocampus, blocking their ability to combine with dopamine receptors.

“Our hypothesis is that this dissociation between ghrelin and dopamine receptors may be what is affecting cognition in Alzheimer’s patients,” Du said. “As the brain loses the function of ghrelin receptors due to amyloid beta, the body tries to compensate by increasing the production of ghrelin and the number of ghrelin receptors. But the amyloid prevents the receptors from functioning.”

Du likened the condition to insulin resistance found in individuals with type 2 diabetes. In that disease, insulin receptors malfunction.

“To compensate, patients in the early stages of type 2 diabetes produce more insulin to bind insulin receptors,” Du said. “But they become insulin-resistant. No matter how much insulin your body produces, the insulin receptors are unable to activate the downstream biochemical reactions needed to transport glucose from blood into cells.

“Similarly, based on our findings, Alzheimer’s might be linked to ghrelin resistance.”

Du said the new findings help explain why a recent clinical trial of a compound called MK0677 — designed to activate ghrelin receptors in the brain — proved unable to slow the progression of Alzheimer’s.

To test a different approach in their mouse model of AD, Du’s team gave the mice MK0677 and another compound — SKF81297 to activate dopamine receptors — at the same time.

“When we gave these compounds simultaneously, we saw improved cognition and memory in the AD mice, and lesions in the hippocampus were reduced,” Du said. “Activating both receptors at the same time was key; it restored the receptors’ ability to form complexes. When this happens, we suspect the ghrelin receptor becomes protected and can no longer bind to amyloid beta.

This shows hippocmapal neurons

‘Hunger Hormone’ Linked to Memory in Alzheimer’s Study

 


Connie’s notes:  Many Parkinson’s and Alzheimer’s clients of Motherhealth caregivers love ice cream in the middle of the night. They are hungry at night.

Why I train Motherhealth caregivers on massage and healthy soups

As a caregiver, I observed that many seniors never had a massage and are left home alone. They have aches and pains and never learned how to massage their own bodies.

We train Motherhealth caregivers, 408-854-1883 , in massaging seniors to offer caring hands that can help them heal and feel loved.

We use ginger, coconut oil, essential oils of eucalyptus and rosemary mixed in apricot or almond oil.

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Top health hacks 9-4-2019

About Motherhealth bay area caregivers
Be cancer-free 40 years before it strikes, more health hacks at ebook
Philippines Coconut Wine -Tuba
29 Senior Discounts You Did Not Know About
Eggplant and apple cider vinegar for skin cancer
Home page / Archives
Alcohol Abuse Linked to Sepsis, Mortality in Critical Patients
Affordable senior housing in the bay area
MEDICATIONS TO AVOID that worse PD (Parkinson’s disease)
Hunched posture in Dementia and Parkinsons
Anabolic and catabolic process, hormones and exercise
The MIND vs. the Mediterranean Diet
Signs of the preactive and active phase of dying, medications for terminally ill
How to support healthy bile production
Browning or caramelized sugar is a carcinogen
Excessive sweating and Parkinsons
Lyme Disease by Dr Mercola
Herbal oil for Lice, Scabies and skin issues
Care plan
Tryptophan – Niacin – NAD = Anti-aging
IRS-1 protein in blood, indicative of Alzheimer
Iron and sweet wormwood herb kill breast cancer cells in 16hrs
Boron fights radiation by Dr Mercola
Anti-aging Vitamin B3, Niacin
Increase the body’s oxygen carrying capacity with exercise, EPO and whole foods
Dark purple berries or Black currant juice and eggs for upping up sex drive
Leg cramps, heart muscles, magnesium and CQ10
Rheumatoid Arthritis by Dr Mercola
Healing your kidneys – Dr Mercola
Can balsamic vinegar help with gout?
Teeth marks on the side of the tongue and liver inflammation
Pineapple, celery, carrots and Arthritis
Income Planning for retirement
Sleep, Vitamin C, hydration for migraine
Under-ripe bananas, uncooked oats, white beans and lentils – healthy
Circadian clock alters response to diet and changes to gut microbiome
NAC, activated charcoal , sleep and parasites
DMSO, hydrogen peroxide and Vit C fight cancer cells
Apple cider vinegar kills parasites, cleansing to the liver and prevents stroke
Gut health – green bananas, mangoes and papayas
Nitric Oxide Dump Exercise with nose breathing to lower blood pressure and thin blood
Zinc and lemongrass for skin health issues
Slimy veggies, saluyot and okra fight cancer

Affordable senior housing in the bay area

We are gathering interested investors who wanted to provide affordable senior housing in the bay area.

Those with better FICO scores and those passive investors are welcome.

We will consider modular and senior safe building spaces.

Your suggestions are welcome. Email Connie at motherhealth@gmail.com , subject: affordable senior housing investing in the bay area. Motherhealth LLC

Motherhealth Inc 501c3 is seeking car donations for senior home care. Email motherhealth or snail mail at PO Box 3138 Saratoga CA 95070 or text 408-854-1883

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How to support healthy bile production

  1. To thin bile: cooked beets, artichokes, sunchokes, carrots, apples.
  2. To flush the liver and gallbladder of congested bile: cooked leafy greens, arugula, fresh lime/lemon juice, aloe vera juice, grapefruit.

 

Bile Salts in Your Body: Function, Benefits, and More


https://www.healthline.com › health › bile-salts

How to Keep Your Bile Thin and Moving? – Divya Alter


divyaalter.com › resources › how-to-keep-your-bile-thin-and-moving

What to Eat to Produce More Bile in the Liver | Livestrong.com


https://www.livestrong.com › Health › Liver Conditions › Hepatitis C

Bile Formation and Secretion – NCBI – NIH


https://www.ncbi.nlm.nih.gov › pmc › articles › PMC4091928

These studies estimated that man produced ~750mL of bile daily and that ~75% …. hormones like secretin that stimulate HCO3 and fluid secretion from the bile …
Bile function and liver: Foods that help increase bile production


Why Proper Bile Flow in Your Body is Essential for Getting Rid …


https://bodyecology.com › articles › why_proper_bile_flow_essential_for_…

Foods That Increase Bile Flow | Healthy Eating | SF Gate


https://healthyeating.sfgate.com › Diet › Digestion

Bile reflux – Diagnosis and treatment – Mayo Clinic


https://www.mayoclinic.org › diagnosis-treatment › drc-20370121

Secretion of Bile and the Role of Bile Acids In Digestion


http://www.vivo.colostate.edu › hbooks › pathphys › digestion › liver › bile

Diet and Herbs for Healthy Bile Production – Ayurvedic Diet …


https://www.joyfulbelly.com › Ayurveda › article › Diet-and-Herbs-for-He…

29 Senior Discounts You Did Not Know About

29 Senior Discounts You Did Not Know About

Wednesday, September 4, 2019 Senior Discounts

Senior Discounts are one of the few truly great perks that come with getting older. You have paid full price your whole life, you deserve a discount! Tons of companies offer special deals, just for those of a certain age. With some companies, you’ll need to be 50, while others start offering their discounts at age 55, 60 or 65.
A little digging online will yield some great results. You will be surprised, how much you can save by simply asking “Do you offer any Senior Discounts?”. We have put together a great list of the best senior discounts, freebies and savings there is to offer. This can range from getting a discount on your groceries, to discounts on going to the movies to everyday costs at the grocery store. Make sure to read through to the end, as there are many you probably didn’t know about!
As always, if you know anyone that could benefit from these savings, share with them using the buttons below.


1. Claim Your Free Home Security System For Just The Cost Of Installation.

If you have ever had anything stolen from you, you know the sense of helplessness and anger that comes along with it. Can you imagine someone breaking into your home? According to a recent survey there is a home intrusion in the United States, *once every 13 seconds! . A recent study shows, simply by having a security system installed, you are 3.5 times less likely to be subject to a burglary. Makes sense, most robbers are going for low hanging fruit, so when the see the sign in your lawn, they are likely to just move along to an easier catch. The good news is, we have you covered. We have teamed up with ADT, and they have an amazing promotion going on right now, where they are offering $850 worth of equipment for free, along with a $100 VISA gift card for signing up for their service. Visit here to learn more about this awesome offer. Protip: Simply having a security system installed will most likely lower your home owners insurance. Make sure to call your insurance company and get your discount after you take advantage of this offer.

2. Save An Average Of $3252 /Year Off Your Mortgage With The New Government “Enhanced Relief” Program

If you’re a homeowner, this one thing could save yourself thousands of dollars this year… Congress recently passed a new government program called the Freddie Mac Enhanced Relief Refinance (FMERR) initiative. This program is designed to help the average American homeowner reduce their payments by an average of $3,252/year (or $271/month). There’s no telling when the program could expire, so it’s suggested that homeowners visit the free Enhanced Relief Savings website to check their eligibility right away. So while the banks happily wait for this program to end, the Government is making a final push and urging homeowners to take advantage. This program is currently active but could be shut down at any given time. The good news is that once you’re in, you’re in. Checking your eligibility is quick and completely free!

3. Discount On Eating Out

If you don’t feel like cooking be sure to turn to these places for good senior dining deals. From fast food to steak restaurants, our compiled restaurant list will definitely help you make your choice. Keep in mind that deals may vary at participating locations and can change without notice.

  • McDonald’s: discounts on coffee and beverages (55+)
  • Whataburger: free drink with purchase of a meal, depending on location (55+)
  • Wendy’s: give free coffee or other discounts depending on location
  • Piccadilly Cafeteria: 10% discount with “Prime Time for Seniors” card
  • IHOP: 10% discount (55+) and a menu for people aged 55 and over at participating locations
  • Krispy Kreme: 10% off (50+) (age and discount varies depending on location)
  • Subway: 10% off (60+) varies by location Reported By Our Reader
  • The Old Spaghetti Factory: Spaghetti Factory “Senior Menu” offers discounted list of menu items
  • Uno Pizzaria & Grill: “Double Nickel Club” 25% off on Wednesday (55+)
  • Sizzler: Offers “Honored Guest Menu” (60+) varies by location
  • Old Country Buffet: Daily discounts for seniors (55+)
  • Friendly’s Restaurants: 10% off meal w/ free coffee at breakfast or free small sunday during non-breakfast hours
  • Fazoli’s: Join “Club 62” for special senior menu items (62+)
  • KFC: free small drink with any meal depending on location (55+)
  • Country Kitchen: Great Senior Menu (55+)
  • Burger King: 10% discount on purchase depending on location (60+)
  • Golden Corral and Del Taco: Automatically 10% discount. — reproted by our reader: James OBrien

4. Get A Walk-In Bathtub At A Big Discount

Walk-in tubs are designed to satisfy the needs of seniors, the disabled, handicapped or anyone with mobility challenges. Statistics say that falls occur in your bathroom more often than in any other room in your house. The Center for Disease Control tells us that two-thirds of bathroom injuries happen near your tub or shower. Usually, they occur when you step over your tub wall or slip on a wet floor, or when you lean on a glass door that wasn’t designed to support your weight. These bathroom injuries increase after you turn 55. Often when your eyesight starts to fade, and you have less mobility and balance. The bottom line? One in three adults over 55 experience falls each year. Right now, many Walk-in Tub manufacturers are offering big discounts to seniors. You can get a free quote on a Walk-in Tub by visiting this website.

5. Save Up To 70% On Life Insurance

Do you have loved ones that depend on you? Are you doing everything to ensure they will be financially stable if the worst happens? While most Americans consider life insurance a necessity, not all Americans have a policy and fewer yet have secured the best possible deal on their plan. Whether you are a homeowner, business owner, or your family’s primary provider, you should protect those that matter the most with a policy that best fits you and your loved ones’ needs. Obtaining life insurance should be one of the most critical decisions for your family’s future – why not get that sense of security at the best possible rate and with maximum coverage? The best way to ensure you are getting the best deal possible is to shop online and compare all your options. In most cases, you may qualify for up to $250,000 of life insurance coverage for as low as $15 per month. Two minutes is all it takes to learn how you can protect your family at the best possible cost.

6. Saving Thousands On Your Car Insurance

You might not know but a lot of insurance companies offering discounts for Seniors with good driving records. The easiest way to find out the most affordable rates is to compare insurance plans on this website. Lot of people are already taking advantage of this free service and saving a ton of money each year! Also don’t forget that if you cancel your current policy before the end date, you’re usually entitled to a refund of the remaining balance.

7. Bathroom Remodels In 1 Day – Skip The Mess & Hassle – Get A Free Quote And Save Thousands

You have probably heard that new technology is allowing people to remodel their bathrooms in as little as 1 day. This allows senior homeowners to avoid the inconvenience and mess of weeks of construction while replacing an old tub with a sleek new upgrade. Finding the right contractor for your bathroom remodel can be complicated. From shower conversions to custom mobility and safety requirements, the options and prices range considerably. Instead of spending hours researching online, you can use this website to compare options, and find quality providers that work in your local area.

8. Stop Paying For Covered Home Appliance Repairs

Many seniors don’t have enough money lying around to pay for expensive home repairs. Your home insurance won’t cover your washing machine or AC breaking. What if your heater breaks when you need it the most? Who has hundreds or even thousands available at a moment’s notice for unscheduled repairs? For this reason, many homeowners are getting this new Home Warranty Program, and they’re ending up saving thousands in the long run. ACs, electrical heaters, appliances, roofing repairs. If there’s something they can’t fix, most likely they will replace it.

9. Help Protect Your IRA Or 401(K) By Learning How To Invest In Physical Gold (Free Investors Guide)

Smart USA investors are quickly learning how to take control of their own retirement finances and AVOID putting all their retirement money into the stock market (which can crash at any time just like it did in 2008). The solution that many of the top investors have turned to is learning how to invest in physical gold. If you don’t currently understand how to invest in physical gold, there is good news: You can now learn a lot faster than you think! This Free Gold Investment Guide (available for a limited time) makes it fast, easy and FREE to get the information you need to learn about investing in physical gold. Income creation + wealth protection from sudden market downturns are two of the biggest advantages as to what makes gold investing so attractive. *It’s free to claim your free gold investing guide* –> Get Your Free Guide Now

10. Owe More Than 10k In Tax Debt? Read This Now!

There are few things scarier than owing money to the government… and tax debt can become a horrendous problem if not taken care of promptly. If YOU have more than 10k in tax debt, then it’s crucial you check out Fresh Start Initiative today. Fidelity Tax Defense can help you solve your IRS tax problems, and provide expert help and relief in in dealing with the IRS and getting a fresh start. They assist with resolving back taxes, liens, penalties, and more, and can even help you save on what you owe the IRS. Click here to get help from Fidelity Tax Defense today!

11. Have The IRS Reduce Your Tax Debt If You Are Veterans

The IRS offers many programs to help you get tax debt relief. Utilizing these programs can give you the ability to help lower your tax debt. The one catch is though, you have to know about the programs to take advantage of them. Veterans Tax Services will help you reduce the amount of tax debt that you owe, and get you on the right track. Get the tax relief you fought for! Right now they are offering to take a look at your specific situation to see if they can help. Visit here to set up a free consultation, to help reduce your tax debt.

12. Health Insurance Savings

Health insurance is now available to more Americans than ever before. Subsidized options are easily available to low-income individuals and families. In the past, many people took the risk of not being insured, but with the Affordable Care Act (ACA) you can be fined if you don’t have qualified health care insurance. Instead of paying a fine, people who have not been able to afford insurance before are looking for affordable medical insurance options. Whether you have low, mid, or high income, you could greatly reduce your health insurance by using HealthInsurance.net to compare policies and prices, and find what’s best for you. Average savings per month: $321/person, $833/family

13. Find Sophisticated 50+ Singles In Your Area – Register For Free

Now thanks to the internet and NEW technology, It’s now easier than ever to meet your perfect match online. One of the top-rated online dating sites for seniors is Silver Singles. They have agree to offer our readers a free trial membership so you can take a peek at who is out there in your local area. If you’re over 50 and single, this can be an amazing opportunity to help you meet like-minded people who are committed to finding someone that they truly want to spend their life with. Silver Singles can help you meet that special someone, so jump over and create a free profile today and have some fun!

14. Go Shopping

You might be surprised to learn that a lot of trendy shops give a senior citizens discount. At Banana Republic, if you over 50-years old you can get a 10% discount at stores, simply by asking for it.

  • Bealls Outlet Senior Discounts: 15% off every Tuesday 50+
  • Belk: 15% off first Tuesday of every month 62+
  • Bon-Ton Department Stores: 15% off on senior discount days; 20% if you use the store’s proprietary credit card 55+
  • C.J. Banks/Christopher Banks: 10% off every Wednesday 60+
  • Clarks: 10% off 62+
  • Dressbarn: 10% off Tues and/or Wed call ahead-varies by location – 55+
  • Goodwill: 10% – 20% off one day a week date varies by location – 55+
  • Hallmark: 10% off one day a week date varies by location; age may vary depending on the product
  • iParty: 10% senior discount every day; ask for discount as soon as you get to the checker
  • Kohl’s: 15% off on Wednesdays 60+
  • Michael’s: 10% off every day with AARP card – 55+
  • Modell’s Sporting Goods: 10% off every day 65+
  • Ross Stores: 10% off every Tuesday 55+
  • The Salvation Army Thrift Stores: Up to 50% off , days vary 55+
  • SteinMart: 20% off red dot/clearance items first Monday of every month 55+
  • TJ Maxx Senior: 10% on Mondays FLORIDA only at this time – 55+
  • Walgreens: 20% off once a month, “Balance Rewards” card required. 65+ and AARP

15. Negotiate Your Current Debt Down To Save Money

Stepping into retirement can be pretty daunting. Doing it with existing unsecured debts can make it even more of a challenge. Debt Settlement allows you to combine all your unsecured debts into a single monthly payment. Generally this allows for much lower payments on a monthly basis than the sum total of the separate debts – making life a lot more manageable. There are many firms out there who will walk you through the process making it simple and painless. If you have more than $15,000 in debt then this is something you should do right away, compounding interest is NOT your friend.

16. Get Government Rebates To Go Solar And Cut Your Energy Bill

Did you know you can significantly reduce your monthly electric bill and pay nothing for it? If you live in a qualified zip code, you can get great rebates by going solar! . Thanks to a little-known government program called the Solar Income Tax Credit, homeowners who live in specific zip codes are getting thousands in rebates to install solar panels. Many people were shocked that subsidies and rebates can cover a good percentage of costs associated with installation, so it costs very little to have done. Learn more about this program and check if your zip code qualifies. Senior homeowners can save $1,000’s of dollars just by using this program.

17. Discounts On Prescriptions

There are actually great discounts out there on your prescriptions. Here are the best of the best…

  • AARP: With the AARP Prescription Discount Card, members can typically save on average 61% on FDA-approved generic, brand name and speciality drugs.
  • Rite Aid: Sign up for the Rite Aid RX Savings program. Save 20% on thousands of brand-name and generic prescription drugs. See store for more details.
  • Costco Member Prescription Program: Costco has a prescription savings program for you and your family. It allows Costco members, who have no prescription drug insurance or whose insurance does not cover all of their prescription medications to save up to 80%
  • CVS Pharmacy: Enroll in CVS Extra Care Saving and Rewards program. You will receive “ExtraSavings” through personalized coupons delivered on reciepts, and online. They also offer 2% cash back in ExtraBucks Rewards
  • Walgreens: For the membership fee of $20 individual or $35 family, you can get special discounts off the cash price of thousands of brand-name and generic medications. Additionaly, If you don’t save at least the cost of your membership fee, they will refund you the difference.
  • Walmart Pharmacy: Walmart pharmacies offer low-cost generic prescriptions that can save you money. Their normally low price, usually beats out alot of their competitiors!

18. FREE Membership To Senior Discount

Senior Discount membership gives you access to huge discounts, deals, coupons and more. Sign up below to get the latest deals on healthcare, home appliances, electronics, groceries, restaurant discounts and much more. Unlike AARP, membership to Senior Discount is completely free (no strings attached). When you sign-up you will get a free e-mail newsletter updates sent to your inbox with the latest discounts and deals. To join for free, simply enter your e-mail below and click “SUBSCRIBE”:


19. Stop Paying For Expensive Auto Repairs

When you buy a car, you usually get a 3-year/36,000 mile warranty, but what happens when that warranty ends? No more roadside assistance and you have to pay for costly repairs out of pocket. If you don’t know anything about cars, you really are at the mercy of the mechanic. Avoid dealing with this hassle and paying for the repairs again by extending your car’s warranty. Even better is going direct to the auto warranty company, rather than going through a middleman. Platinum Auto Warranty are one of the few direct providers of the program, and we like them because they are catering directly to seniors. Visit here to learn more about their auto warranty program.

20. Seniors Who Own Their Home Can Save On Window Replacements

Compare Window Prices and Installation Costs. Homeowners can save nearly 40%. Get quotes from up to four pre-screened, licensed, & insured contractors. Get a quote today and see how much you could save! Visit Here to learn more.

21. Save On Groceries

Take full advantage of your senior discount at your local grocery store. Lots of stores offer it – you need to ask! Keep in mind that discounts and deals may vary and can change without notice.

  • Farm Fresh: 5% discount Tuesdays and Thursdays (55+)
  • American Discount Stores 10% Off Every Monday 62+
  • Bi-Lo: 5% Off Every Wednesday 60+
  • Hy-Vee: depending on location will usually offer 5% discount on Tuesdays and Wednesdays (some stores set age to 65+)
  • Fred Meyer: 10% senior discount on the first Tuesday of every month
  • New Seasons Market: 10% discount every Wednesday
  • Compare Food Supermarket: 10% discount in participating locations, get in touch with your local store to find out more
  • Piggly Wiggly: varying discounts at participating locations
  • Publix: 5% Off Every Wednesday In Certain States. Always Ask! –reported by our reader:Alice Galloway
  • Fry’s Food: 10% discount on the first Wednesday of every month to all seniors with VIP card.

22. Save On Medical Bills

Healthcare is an essential part of human life, and the costs of prescriptions add up more and more as you age. Most retirees need to take some form of medication, so it’s only right that you should be able to get a discount on your pills. By choosing the right insurance company for your needs, you could get your prescription drugs covered. Also, many seniors may not know this, but they may be eligible to get extra benefits out of their Medicare insurance plan. You can also check if you qualify for vision, dental, hearing or even arthritis treatment coverage.

23. Save On Cruises

Carnival Cruises, Royal Caribbean, Costa Cruises Is there any better way to celebrate life than to venture out at sea? Cruises are wonderful with their all-inclusive travel options where you get to sit back, have a drink or two for free, soak up the midday sun and enjoy some high-class cuisine along with various live music performances. Cruise lines offer a huge variety of discounts for senior citizens, and this includes some of the most well-known companies like Carnival Cruises and Royal Caribbean, offering exclusive deals to citizens over the age of 55. You will be able to get a cruise deal anywhere in the world, be it the Caribbean or even the icy Alaska. Keep in mind that not all cruises have discounts, so it is best to check with the specific cruise company.

24. Learn Angel Investment From Mentors

“Shark Tank” investor Robert Herjavec and Neil Patel(The Wall Street Journal calls him a top influencer on the web, Forbes says he is one of the top 10 marketers, and Entrepreneur Magazine says he created one of the 100 most brilliant companies. He was recognized as a top 100 entrepreneur under the age of 30 by President Obama and a top 100 entrepreneur under the age of 35 by the United Nations.) teach you how to invest the most hottest startup. Watch the video here. How $50 can be turned into $20,000 by making the right picks.

25. FIXD – Save $1000s On Costly Auto Repairs

Have you ever gone to an auto repair shop for an oil change, only to have the mechanic say you need to fix something completely unrelated? Or has the mysterious “check engine” light come on, and the next thing you know the mechanic has a list of expensive engine parts that need replacing? Every car made after 1996, has special port, that sends valuable diagnostic information on any problems with your car. Fixd connects to this port, then communicates with you via its smartphone app to tell you all the detailed information. It’s a great way to confirm or deny, any expensive repairs that a mechanic is trying to charge you for. Stop paying for unnecessary car repairs!

26. This Genius Device Let’s You Communicate In More Than 40 Languages!

Whatever your reason for traveling is- the ability to engage and communicate with others in their own language is a huge advantage. Luckily, two famous Japanese inventors took language translation to the next level and created an instant translator called MUAMA Instant Translator. It can easily translate real-time speech into over 40 languages using only a few finger-taps. You don’t need to know or learn another language to be able to communicate in it. Difficulties, caused by language barriers, will soon be a thing of the past! What could be better than this?

27. Get Thousands Back – Get Rid Of Your Timeshare!

If you’re stuck with a Timeshare you never use, let the experts help you get your money back instead of struggling alone. My Timeshare Options enables you to recoup the cost of your Timeshare by providing all the resources you need. Get a free quote with no risk and no obligation through My Timeshare Options and let the experts tell you how to get thousands of dollars back on your investment. Just enter your information to get your free quote!

28. Roundup Linked To Cancer – You May Receive Significant Compensation

If you or a loved one were diagnosed with any type of Non-Hodgkin’s Lymphoma after using Roundup, significant financial compensation might be available to you. Complete the evaluation now. Complete this free evaluation now.

Bonus #1 – Tour National Parks

Yosemite, Yellowstone, The Grand Canyon, Zion, The Everglades & More With this fantastic perk, over 62s can use their age advantage to score a severe discount at America’s National Parks. It’s time to tour Yellowstone, senior citizens; you can get an annual pass for just $20 and a lifetime pass for $80. This pass gives seniors access to all 2,000 federal recreation sites, including National Forests and grasslands. You’ll be able to visit all of America’s parks through-out your retirement. The cost of the pass covers your entrance-fee, camping, usage fees for a driver and all passengers. You can take the grandkids camping for free whenever you like. Enjoy wildlife, gorgeous scenery and some well-earned peace.

Fast heart beat from presence of molds, fungi, parasites and other toxins

Signs of fast heart beat

  • Shortness of breath.
  • Lightheadedness.
  • Rapid pulse rate.
  • Heart palpitations — a racing, uncomfortable or irregular heartbeat or a sensation of “flopping” in the chest.
  • Chest pain.
  • Fainting (syncope)

Damp buildings often have a moldy smell or obvious mold growth; some molds are human pathogens. This has caused concern regarding health effects of moldy indoor environments and has resulted in many studies of moisture- and mold-damaged buildings. Recently, there have been reports of severe illness as a result of indoor mold exposure, particularly due to Stachybotrys chartarum. While many authors describe a direct relationship between fungal contamination and illness, close examination of the literature reveals a confusing picture. Here, we review the evidence regarding indoor mold exposure and mycotoxicosis, with an emphasis on S. chartarum. We also examine possible end-organ effects, including pulmonary, immunologic, neurologic, and oncologic disorders. We discuss the Cleveland infant idiopathic pulmonary hemorrhage reports in detail, since they provided important impetus for concerns about Stachybotrys. Some valid concerns exist regarding the relationship between indoor mold exposure and human disease.

Review of the literature reveals certain fungus-disease associations in humans, including ergotism (Claviceps species), alimentary toxic aleukia (Fusarium), and liver disease (Aspergillys). While many papers suggest a similar relationship between Stachybotrys and human disease, the studies nearly uniformly suffer from significant methodological flaws, making their findings inconclusive. As a result, we have not found well-substantiated supportive evidence of serious illness due to Stachybotrys exposure in the contemporary environment. To address issues of indoor mold-related illness, there is an urgent need for studies using objective markers of illness, relevant animal models, proper epidemiologic techniques, and examination of confounding factors.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC145304/

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Artificial light use when sleeping is link to obesity

We have to turn off all lights to sleep to signal our pituitary glands in the brain that it is night time which will kick in the natural rhythm of day and night. When we get adequate sleep, our brain and body can detox or get rid of toxins.

So inadequate sleep can lead to other health issues including obesity.

When we have parasites and other bad microbes, they disrupt the natural rhythms of day and night and we don’t get adequate sleep at night.
Some of our Parkinson’s clients wake up in the middle of the night to snack of ice cream, it is the bad microbes in the gut telling them to consume sugar and disrupting the biorhythm of night and day so that we can sleep at night.

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