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Iron overload, organs affected and related health issues

Organs commonly affected by haemochromatosis are the liver, heart, and endocrine glands.[3] Haemochromatosis may present with the following clinical syndromes:[4] Cirrhosis of the liver: Varies from zonal iron deposition[5] to fibrosis (cirrhosis). Diabetes due to selective iron deposition in pancreatic islet beta cells leading to functional failure and cell death.[2][6] Cardiomyopathy Arthritis, from calcium pyrophosphateContinue reading “Iron overload, organs affected and related health issues”

Copper toxicity and mental diseases

Inflammation and damage to nerve cells in brain tissue Iowa State University researchers have described with single-molecule precision how copper ions cause prion proteins to misfold and seed the misfolding and clumping of nearby prion proteins. The researchers also found the copper-induced misfolding and clumping is associated with inflammation and damage to nerve cells inContinue reading “Copper toxicity and mental diseases”