You are subscribed to receive research study announcements from the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland. To learn more about the study below, or other studies, please call us at 1-866-444-1132.

Study for women who are at risk of developing breast cancer

A research team at the National Institutes of Health (NIH) in Bethesda, Maryland seeks women who are at risk for developing breast cancer. Researchers are collecting and studying breast duct cells to try to determine what early changes occur in these cells on the way to becoming breast cancer. Hopefully this will allow us in the future to understand how breast cancer develops by improving methods for determining risk, and ultimately preventing breast cancer.

You may be eligible if you meet one of the following:

• Your doctor has told you that you are at an increased risk for developing breast cancer
• A history of breast cancer in one breast
• Have had ductal carcinoma in situ or lobular carcinoma in situ
• A breast biopsy that showed atypical hyperplasia or abnormal cells
• Have a Gail Index for increased risk for breast cancer
• Have a close family member with a history of breast cancer (mother, sister, aunt)

Study participation includes:

• 1 screening phone call
• Review of your medical records by the study team
• A 1-hour, outpatient screening visit
• Routine blood work
• A 3 to 4-hour, outpatient procedure to collect cells from the breast ducts
• Analysis of the cells for changes in their structure, DNA, and gene expression
• All study-related procedures are provided at no cost
• Compensation for participation

All tests and procedures are performed at the NIH Clinical Center, America’s Research Hospital in Bethesda, Maryland. We are on the Metro red line (Medical Center stop).

For more information, call:
Office of Patient Recruitment
1-866-444-1132
Online: clinicaltrials.gov and search by study 02-C-0077

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