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Inhibition of human aromatase (estrogen synthetase) by plant Flavone (flavonoids), for breast cancer prevention

Flavone and isoflavone phytoestrogens are plant chemicals and are known to be competitive inhibitors of cytochrome P450 aromatase with respect to the androgen substrate. Aromatase is the enzyme that converts androgen to estrogen; therefore, these plant chemicals are thought to be capable of modifying the estrogen level in women. The study concluded that Flavones areContinue reading “Inhibition of human aromatase (estrogen synthetase) by plant Flavone (flavonoids), for breast cancer prevention”