Affordable in home care | starts at $28 per hr

408-854-1883 starts at $30 per hr home care

Marketplace

Soon

408-854-1883 text

Marketplace

Soon

Book an Appointment

Vagus nerve health = healing sounds, back bends,pickled veggies,massage

Posted byconnie dello buonoPosted inMenu

vagus nerve 101

vagus nerve and inflammation p4vagus nerve and inflammation p3vagus nerve and inflammation p2vagus nerve and inflammation

back bendsback bends belly breaths yoga calming musicvagus nerve

 

 

 

References

  • 1 Lotze MT, Tracey KJ. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 2005; 5: 331–42.
  • 2 Yang H, Hreggvidsdottir HS, Palmblad K et al. A Critical Cysteine is Required for HMGB1 Binding to TLR4 and Activation of Macrophage Cytokine Release. Proc Natl Acad Sci USA 2010; 26: 11942–7.
  • 3 Medzhitov R. Inflammation 2010: new adventures of an old flame. Cell 2010; 140: 771–6.
  • 4 Borovikova LV, Ivanova S, Nardi D et al. Role of vagus nerve signaling in CNI-1493-mediated suppression of acute inflammation. Auton Neurosci 2000; 85: 141–7.
  • 5 Borovikova LV, Ivanova S, Zhang M et al. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 2000; 405: 458–62.
  • 6 Tracey KJ. The inflammatory reflex. Nature 2002; 420: 853–9.
  • 7 Huston JM, Ochani M, Rosas-Ballina M et al. Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis. J Exp Med 2006; 203: 1623–8.
  • 8 Wang H, Yu M, Ochani M et al. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 2003; 421: 384–8.
  • 9 Bernik TR, Friedman SG, Ochani M et al. Pharmacological stimulation of the cholinergic antiinflammatory pathway. J Exp Med 2002; 195: 781–8.
  • 10 Bernik TR, Friedman SG, Ochani M et al. Cholinergic antiinflammatory pathway inhibition of tumor necrosis factor during ischemia reperfusion. J Vasc Surg 2002; 36: 1231–6.
  • 11 van Westerloo DJ, Giebelen IA, Florquin S et al. The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice. Gastroenterology 2006; 130: 1822–30.
  • 12 van Westerloo DJ, Giebelen IA, Florquin S et al. The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis. J Infect Dis 2005; 191: 2138–48.
  • 13 Huston JM, Gallowitsch-Puerta M, Ochani M et al. Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis. Crit Care Med 2007; 35: 2762–8.
  • 14 Yeboah MM, Xue X, Duan B et al. Cholinergic agonists attenuate renal ischemia-reperfusion injury in rats. Kidney Int 2008; 74: 62–9.
  • 15 van Maanen MA, Lebre MC, van der PT et al. Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice. Arthritis Rheum 2009; 60: 114–22.
  • 16 Mioni C, Bazzani C, Giuliani D et al. Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats. Crit Care Med 2005; 33: 2621–8.
  • 17 Guarini S, Cainazzo MM, Giuliani D et al. Adrenocorticotropin reverses hemorrhagic shock in anesthetized rats through the rapid activation of a vagal anti-inflammatory pathway. Cardiovasc Res 2004; 63: 357–65.
  • 18 Guarini S, Altavilla D, Cainazzo MM et al. Efferent vagal fibre stimulation blunts nuclear factor-kappaB activation and protects against hypovolemic hemorrhagic shock. Circulation 2003; 107: 1189–94.
  • 19 Ottani A, Giuliani D, Galantucci M et al. Melanocortins counteract inflammatory and apoptotic responses to prolonged myocardial ischemia/reperfusion through a vagus nerve-mediated mechanism. Eur J Pharmacol 2010; 637: 124–30.
  • 20 Li J, Xie H, Wen T, Liu H, Zhu W, Chen X. Expression of high mobility group box chromosomal protein 1 and its modulating effects on downstream cytokines in systemic lupus erythematosus. J Rheumatol 2010; 37: 766–75.
  • 21 Tracey KJ. Understanding immunity requires more than immunology. Nat Immunol 2010; 11: 561–4.
  • 22 Parrish WR, Rosas-Ballina M, Gallowitsch-Puerta M et al. Modulation of TNF Release by Choline Requires Alpha7 Subunit Nicotinic Acetylcholine Receptor-Mediated Signaling. Mol Med 2008; 14: 567–74.
  • 23 de Jonge WJ, van der Zanden EP, The FO et al. Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway. Nat Immunol 2005; 6: 844–51.
  • 24 Wang H, Liao H, Ochani M et al. Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nat Med 2004; 10: 1216–21.
  • 25 Huston JM, Wang H, Ochani M et al. Splenectomy protects against sepsis lethality and reduces serum HMGB1 levels. J Immunol 2008; 181: 3535–9.
  • 26 Rosas-Ballina M, Tracey KJ. The neurology of the immune system: neural reflexes regulate immunity. Neuron 2009; 64: 28–32.
  • 27 Rosas-Ballina M, Ochani M, Parrish WR et al. Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia. Proc Natl Acad Sci USA 2008; 105: 11008–13.
  • 28 Huston JM, Rosas-Ballina M, Xue X et al. Cholinergic neural signals to the spleen down-regulate leukocyte trafficking via CD11b. J Immunol 2009; 183: 552–9.
  • 29 Saeed RW, Varma S, Peng-Nemeroff T et al. Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J Exp Med 2005; 201: 1113–23.
  • 30 Brigden ML, Pattullo AL. Prevention and management of overwhelming postsplenectomy infection–an update. Crit Care Med 1999; 27: 836–42.
  • 31 Tracey KJ. Suppression of TNF and other proinflammatory cytokines by the tetravalent guanylhydrazone CNI-1493. Prog Clin Biol Res 1998; 397: 335–43.
  • 32 Pavlov VA, Parrish WR, Rosas-Ballina M et al. Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway. Brain Behav Immun 2009; 23: 41–5.
  • 33 Pavlov VA, Ochani M, Gallowitsch-Puerta M et al. Central muscarinic cholinergic regulation of the systemic inflammatory response during endotoxemia. Proc Natl Acad Sci USA 2006; 103: 5219–23.
  • 34 Li Y, Wu X, Zhu J, Yan J, Owyang C. Hypothalamic regulation of pancreatic secretion is mediated by central cholinergic pathways in the rat. J Physiol 2003; 552: 571–87.
  • 35 Shimazu T, Matsushita H, Ishikawa K. Cholinergic stimulation of the rat hypothalamus: effects of liver glycogen synthesis. Science 1976; 194: 535–6.
  • 36 Sloan RP, McCreath H, Tracey KJ, Sidney S, Liu K, Seeman T. RR interval variability is inversely related to inflammatory markers: the CARDIA study. Mol Med 2007; 13: 178–84.
  • 37 Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Circulation 1996; 93: 1043–65.
  • 38 Gaziano EP, Freeman DW. Analysis of heart rate patterns preceding fetal death. Obstet Gynecol 1977; 50: 578–82.
  • 39 Sampson MB, Mudaliar NA, Lele AS. Fetal heart rate variability as an indicator of fetal status. Postgrad Med 1980; 67: 207–10, 213–15.
  • 40 Lauersen NH, Wilson KH, Bilek A, Rao VS, Kurkulos M. A new modality in nonstress testing: evaluation of beat-to-beat fetal heart rate variability. Am J Obstet Gynecol 1981; 141: 521–6.
  • 41 Kleiger RE, Miller JP, Bigger JT Jr, Moss AJ. Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. Am J Cardiol 1987; 59: 256–62.
  • 42 La Rovere MT, Bigger JT Jr, Marcus FI, Mortara A, Schwartz PJ. Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators. Lancet 1998; 351: 478–84.
  • 43 Schwartz PJ, La Rovere MT, Vanoli E. Autonomic nervous system and sudden cardiac death. Experimental basis and clinical observations for post-myocardial infarction risk stratification. Circulation 1992; 85: I77–91.
  • 44 Garrard CS, Kontoyannis DA, Piepoli M. Spectral analysis of heart rate variability in the sepsis syndrome. Clin Auton Res 1993; 3: 5–13.
  • 45 Schmidt H, Muller-Werdan U, Hoffmann T et al. Autonomic dysfunction predicts mortality in patients with multiple organ dysfunction syndrome of different age groups. Crit Care Med 2005; 33: 1994–2002.
  • 46 Aydemir M, Yazisiz V, Basarici I et al. Cardiac autonomic profile in rheumatoid arthritis and systemic lupus erythematosus. Lupus 2010; 19: 255–61.
  • 47 Stojanovich L, Milovanovich B, de Luka SR et al. Cardiovascular autonomic dysfunction in systemic lupus, rheumatoid arthritis, primary Sjogren syndrome and other autoimmune diseases. Lupus 2007; 16: 181–5.
  • 48 Sharma P, Makharia GK, Ahuja V, Dwivedi SN, Deepak KK. Autonomic dysfunctions in patients with inflammatory bowel disease in clinical remission. Dig Dis Sci 2009; 54: 853–61.
  • 49 Lindgren S, Stewenius J, Sjolund K, Lilja B, Sundkvist G. Autonomic vagal nerve dysfunction in patients with ulcerative colitis. Scand J Gastroenterol 1993; 28: 638–42.
  • 50 Bruchfeld A, Goldstein RS, Chavan S et al. Whole blood cytokine attenuation by cholinergic agonists ex vivo and relationship to vagus nerve activity in rheumatoid arthritis. J Intern Med 2010; 268: 94–101.
  • 51 Goldstein RS, Bruchfeld A, Yang L et al. Cholinergic anti-inflammatory pathway activity and High Mobility Group Box-1 (HMGB1) serum levels in patients with rheumatoid arthritis. Mol Med 2007; 13: 210–5.
  • 52 Jan BU, Coyle SM, Macor MA, Reddell M, Calvano SE, Lowry SF. Relationship of basal heart rate variability to in vivo cytokine responses after endotoxin exposure. Shock 2010; 33: 363–8.
  • 53 Hoeger S, Bergstraesser C, Selhorst J et al. Modulation of brain dead induced inflammation by vagus nerve stimulation. Am J Transplant 2010; 10: 477–89.
  • 54 Dantzer R, O’Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 2008; 9: 46–56.
  • 55 Raison CL, Capuron L, Miller AH. Cytokines sing the blues: inflammation and the pathogenesis of depression. Trends Immunol 2006; 27: 24–31.
  • 56 Miller AH, Maletic V, Raison CL. Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression. Biol Psychiatry 2009; 65: 732–41.
  • 57 Kemp AH, Quintana DS, Gray MA, Felmingham KL, Brown K, Gatt JM. Impact of depression and antidepressant treatment on heart rate variability: a review and meta-analysis. Biol Psychiatry 2010; 67: 1067–74.
  • 58 Bajbouj M, Merkl A, Schlaepfer TE et al. Two-year outcome of vagus nerve stimulation in treatment-resistant depression. J Clin Psychopharmacol 2010; 30: 273–81.
  • 59 Rush AJ, Sackeim HA, Marangell LB et al. Effects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study. Biol Psychiatry 2005; 58: 355–63.
  • 60 Marangell LB, Rush AJ, George MS et al. Vagus nerve stimulation (VNS) for major depressive episodes: one year outcomes. Biol Psychiatry 2002; 51: 280–7.
  • 61 Dowlati Y, Herrmann N, Swardfager W et al. A meta-analysis of cytokines in major depression. Biol Psychiatry 2010; 67: 446–57.
  • 62 Lampert R, Bremner JD, Su S et al. Decreased heart rate variability is associated with higher levels of inflammation in middle-aged men. Am Heart J 2008; 156: 759.e1–7.
  • 63 Haensel A, Mills PJ, Nelesen RA, Ziegler MG, Dimsdale JE. The relationship between heart rate variability and inflammatory markers in cardiovascular diseases. Psychoneuroendocrinology 2008; 33: 1305–12.
  • 64 Carney RM, Freedland KE, Stein PK et al. Heart rate variability and markers of inflammation and coagulation in depressed patients with coronary heart disease. J Psychosom Res 2007; 62: 463–7.
  • 65 Janszky I, Ericson M, Lekander M et al. Inflammatory markers and heart rate variability in women with coronary heart disease. J Intern Med 2004; 256: 421–8.
  • 66 Frasure-Smith N, Lesperance F, Irwin MR, Talajic M, Pollock BG. The relationships among heart rate variability, inflammatory markers and depression in coronary heart disease patients. Brain Behav Immun 2009; 23: 1140–7.
  • 67 Soares-Miranda L, Negrao CE, Antunes-Correa LM et al. High levels of C-reactive protein are associated with reduced vagal modulation and low physical activity in young adults. Scand J Med Sci Sports 2010; July 6. [Epub ahead of Print].
  • 68 Sloan RP, Shapiro PA, Demeersman RE et al. Aerobic exercise attenuates inducible TNF production in

Published by connie dello buono

Health educator, author and enterpreneur motherhealth@gmail.com or conniedbuono@gmail.com ; cell 408-854-1883 Helping families in the bay area by providing compassionate and live-in caregivers for homebound bay area seniors. Blogs at www.clubalthea.com Currently writing a self help and self cure ebook to help transform others in their journey to wellness, Healing within, transform inside and out. This is a compilation of topics Connie answered at quora.com and posts in this site.

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Copyright © 2026 KRM Digital Solutions

Discover more from Affordable in home care | starts at $28 per hr

Subscribe now to keep reading and get access to the full archive.

Continue reading