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Can depression increase Alzheimer’s risk?

Can depression increase Alzheimer's risk? by Emmanuel Fabella

Answer by Emmanuel Fabella:

The relationship between Depression and Alzheimer's is not conclusive, but there is evidence of increased risk, which I present below.
 
As alluded to by other responders, depression can itself cause Pseudodementia, which has its own attendant declines in memory and cognition.
 
Depression and Alzheimer's often coexist, with each condition likely exacerbating the other.
 
A 2008 study published in Neurology found increased risk of Alzheimer's Disease in people with previous episodes of depression, although the authors pointed out that their data could not differentiate between causation and mere association.
 

The study involved 486 people age 60 to 90 who had no dementia. Of those, 134 people had experienced at least one episode of depression that prompted them to seek medical advice.
 
The participants were followed for an average of six years. During that time 33 people developed Alzheimer's disease. People who had experienced depression were 2.5 times more likely to develop Alzheimer's disease than people who had never had depression. The risk was even higher for those whose depression occurred before the age of 60; they were nearly four times more likely to develop Alzheimer's than those with no depression.    

"We don't know yet whether depression contributes to the development of Alzheimer's disease or whether another unknown factor causes both depression and dementia,"  said study author Monique M.B. Breteler, MD, PhD, with the Erasmus University Medical Center in Rotterdam, the Netherlands.  "We'll need to do more studies to understand the relationship between depression and dementia."
 
One theory was that depression leads to loss of cells in two areas of the brain, the hippocampus and the amygdala, which then contributes to Alzheimer's disease. But this study found no difference in the size of these two brain areas between people with depression and people who had never had depression.
 
From: Depression Increases Risk of Alzheimer's Disease

Can depression increase Alzheimer's risk?

Published by connie dello buono

Connie Dello Buono is based in Sunnyvale California. Her first ebook is about women's health, Birthing Ways Healing Ways and her recent one is about cancer prevention, Curated Healing Ways. She had helped women have holistic childbirth as childbirth educator, founded Motherhealth, to serve seniors in the bay area with holistic caregivers and blogs at www.clubalthea.com with more than 10,000 health and finance related posts. Connie trains her own caregivers, which are the favorites of most bay area seniors who are home bound and alone. She is active in the rehab and nursing facilities, volunteering on music and movement for seniors. She is a member of Lion's club and offered scholarships to students in the Philippines. She is active at churchinsunnyvale.us and has Fridays Bible home study in Sunnyvale using the recovery version of the Bible , free at biblesforamerica.us She loves dancing and teaching and her courses can be found at https://teachclub.com/@thriveafter60 She is California Life Insurance licensed providing life insurance for older adults with health issues and helping women retire safely with income for life. at menloassetca.com , she helps with 401k rollover. 3 Benefit plans - Mortgage protection using term life insurance to pay for mortgage balance in event of death - Final Expense plan using Single Issue Whole Life Insurance, with cash back, disability benefit and guaranteed in the presence of health issues - Fixed Index Annuity retirement plan for safe, accessibility, less fees, less taxes, avoids probate as it goes directly to beneficiaries, rate of return with no downside market participation. She brings compassion and understanding to the needs of her clients, bringing holistic approach in health and life insurance. Her goal is to free families from worries especially during covid with caregivers and life insurance in the presence of health issues, especially for women. She can be reached at 408-854-1883 , motherhealth@gmail.com

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