Mediterranean Diet to Prevent Cognitive Decline

Brief Description

This study will determine whether older adults with normal cognition, mild cognitive impairment (MCI), or mild to moderate Alzheimer’s disease can adhere to a Mediterranean diet.

 

Patient Qualifications:

Min Age Max Age Gender Healthy Volunteers
65 Years
N/A
Both
Yes

Inclusion Criteria:

    • Study partner, if diagnosed with MCI or Alzheimer’s disease
    • Body mass index of 20-35
    • English as a primary language
Exclusion Criteria:
    • Serious medical risk
    • Specialized diet regimes
    • Existing Mediterranean diet
Detailed Description:

Participants will follow the study-designed Mediterranean diet for 6 weeks. The diet consists of fruits, vegetables, grains, dairy, olive oils, seafood, and nuts. The diet is also low in red meat and solid fats. Participants will track the food they eat and will be monitored by a registered dietitian.

Locations:
Map Marker City State Zip Code Status Primary Contact
1
University of Kansas Medical Center
Kansas City
Kansas
66160
Recruiting
Kendra Spaeth
913-588-8992
kspaeth@kumc.edu
Agency
University of Kansas Medical Center
Agency
National Institute on Aging (NIA)
Name Role Affiliation
Deborah K. Sullivan, PhD
Principal Investigator
University of Kansas Medical Center
Study Contact:
Name Phone Email
Kendra Spaeth
913-588-8992

Brain health registry

Brief Description

The purpose of the online Brain Health Registry is to recruit and observe people who are interested in promoting healthy brain function through the prevention of brain diseases, disorders, and injuries in adults. Participation involves answering questions about your health, lifestyle, and medical history and taking online brain tests. Researchers hope to build a large pool of potential participants for clinical trials, reducing the time and cost of research. For more information, visit www.brainhealthregistry.org.

Patient Qualifications

 

Min Age Max Age Gender Healthy Volunteers
18 Years
N/A
Both
Accepts Healthy Volunteers
Inclusion Criteria:

None listed.

Exclusion Criteria:

None listed.

 

Detailed Description:

The Brain Health Registry is an online registry for people interested in research on new treatments for Alzheimer’s disease, Parkinson’s disease, depression, post-traumatic stress disorder, and other conditions that affect brain function. Anyone age 18 years and older can join the Brain Health Registry. To enroll, participants complete basic contact and demographic information and consent to participate. After enrollment, participants complete questionnaires about health, lifestyle and medical history, as well as computerized tests of memory, attention, and speed of processing new information and organization.

Participants in the registry will be invited to repeat the questionnaires and brain tests every 3-6 months so researchers can gather information about changes in brain function over time. For most people, participation will take less than 3 hours per year. Currently, the online tests must be taken on a desktop or laptop, not on mobile devices such as tablets and smartphones.

Participants may give researchers permission to access medical records and may provide a saliva sample for genetic screening and a blood sample to better understand general health, but this is optional. They will also learn about future clinical trials that test diagnostic tools or potential treatments for brain disorders and be given an opportunity to participate.

 

Central Contact Information:

For more information, visit www.brainhealthregistry.org. To enroll, visit https://my.brainhealthregistry.org/register

Genematch for preclinical Alzheimer’s disease clinical studies

Patient Qualifications

Min Age Max Age Gender Healthy Volunteers
55 Years
75 Years
Both
Accepts Healthy Volunteers

Inclusion Criteria

    • Willing to provide basic demographic, medical history, and contact information
    • Consent to APOE genotyping without receiving results
    • Resident of the United States

Exclusion Criteria

    • Unable to comply with GeneMatch requirements
    • Self-reported diagnosis of dementia or any other objective cognitive impairment syndrome

Detailed Description

The primary purpose of GeneMatch is to identify and characterize a large group of people who are interested in, and may be eligible to participate in, preclinical Alzheimer’s disease clinical studies and trials based on their genetic background. Participation in these research studies is voluntary.

GeneMatch will provide a cheek swab kit for collecting a genetic sample to determine which copies of the apolipoprotein E (APOE) gene a person has. GeneMatch will use the APOE test results to match enrollees to research studies they may be interested in. GeneMatch will not disclose the results of the APOE test to enrollees, but studies to which enrollees are referred may require such disclosure. All information will remain secure and confidential.

Central Contact Information:

For more information, visit www.endALZnow.org/GeneMatch, or call 1-888-786-7259or email GeneMatch@endALZnow.org