Summary: Researchers have identified a new protein, CIB2, that is key to helping the auditory system to turn soundwaves into meaningful brain signals. Mutations of this gene leave people unable to convert the soundwaves into signals that the brain can interpret, and are deaf. Source: University of Maryland. Study identifies a new protein that isContinue reading “Key Mechanism Behind Some Forms of Deafness Identified”
Category Archives: genes
Hemochromatosis patients should be on a low-iron diet
Hemochromatosis is a common genetic condition and yet there are still a number of misperceptions surrounding the diagnosis and management of this condition. Hemochromatosis affects both men and women. Typical patients do not have alcoholism or viral hepatitis, and often have normal liver enzymes. Clinical expression is highly variable. Genetic testing is widely available andContinue reading “Hemochromatosis patients should be on a low-iron diet”
Metabolism is life sustaining and sum of all chemical reactions for growth and death of cells
Metabolism (from Greek: μεταβολή metabolē, “change”) is the set of life-sustaining chemical transformations within the cells of living organisms. The three main purposes of metabolism are the conversion of food/fuel to energy to run cellular processes, the conversion of food/fuel to building blocks for proteins, lipids, nucleic acids, and some carbohydrates, and the elimination ofContinue reading “Metabolism is life sustaining and sum of all chemical reactions for growth and death of cells”
Levels of DNA methylation reflect a person’s age
Certain DNA changes can better predict a person’s life expectancy than traditional risk factors such as age. The findings could lead to novel insights into the molecular mechanisms of aging and new ways to evaluate methods for slowing the rate of aging. “Epigenetic age” might represent a person’s biological age more accurately than the numberContinue reading “Levels of DNA methylation reflect a person’s age”
Genomic profiling assay for hematologic malignancies and sarcomas
FoundationOneHeme is a comprehensive genomic profiling assay for hematologic malignancies and sarcomas. The test is designed to provide physicians with clinically actionable information to guide treatment decisions for patients based on the genomic profile of their disease. Test results provide information about clinically significant alterations, potential targeted therapies, available clinical trials, and quantitative markers thatContinue reading “Genomic profiling assay for hematologic malignancies and sarcomas”
Calorie restricted diet to live long and healthy
Not only did their calorie restricted diet ( CR) monkeys look remarkably younger – with more hair, less sag, and brown instead of grey – than monkeys that were fed a standard diet, they were healthier on the inside too, free from pathology. Cancers, such as the common intestinal adenocarcinoma, were reduced by over 50%.Continue reading “Calorie restricted diet to live long and healthy”
Immunoglobulin B cells from bone marrow and cytokines role during cancer expression
Antibody (or immunoglobulin) structure is made up of two heavy-chains and two light-chains. These chains are held together by disulfide bonds. The arrangement or processes that put together different parts of this antibody molecule play important role in antibody diversity and production of different subclasses or classes of antibodies. The organization and processes take placeContinue reading “Immunoglobulin B cells from bone marrow and cytokines role during cancer expression”
FOXO3, a gene linked to intelligence and involved in insulin signalling that might trigger apoptosis
Genes linked to intelligence Researchers discovered that the genes that were the strongest linked to intelligence are ones involved in pathways that play a part in the regulation of the nervous system’s development and apoptosis (a normal form of cell death that is needed in development). The most significant SNP was found within FOXO3, aContinue reading “FOXO3, a gene linked to intelligence and involved in insulin signalling that might trigger apoptosis”
Dr Mercola’s book – Fat for Fuel
Dr Mercola’s book ‘Fat for Fuel’ book is a revolutionary diet to combat cancer, boost brain power and increase your energy. Dr Mercola’s story… In 1995, my understanding of chronic disease took a quantum leap. I was introduced to Dr. Ron Rosedale and his breakthrough views on clinical metabolic biochemistry. In a nutshell, Dr. RosedaleContinue reading “Dr Mercola’s book – Fat for Fuel”
Acetylcholine/Choline Deficiency in Chronic Illness – eat soft boiled eggs
To my friends who love to drink alcohol be it San Miguel beer or red wine, do eat protein rich foods like soft boiled eggs when drinking. To my BFF with pancreas health issues, eat soft boiled eggs. Connie Acetylcholine/Choline Deficiency in Chronic Illness – The Hunt for the Missing Egg. Those who lack cholineContinue reading “Acetylcholine/Choline Deficiency in Chronic Illness – eat soft boiled eggs”
Predict disease with WES – ask your doctor to request this DNA lab test
Dear Health Consumer, When you are ready to have a better understanding of your human genome responsible for a majority of known disease-related variants that can help you and your doctor monitor and predict your health and be proactive with disease related challenges in the future to achieve a better health outcome, you may use thisContinue reading “Predict disease with WES – ask your doctor to request this DNA lab test”
Gut health seminar on May 8-15
Dense breasts may be leading risk factor for breast cancer
By Lisa Rapaport (Reuters Health) – Women whose breasts are composed mainly of dense glandular tissue rather than fat may have higher odds of developing breast cancer, a recent study suggests. Researchers examined data on more than 18,000 women with breast malignancies and 184,000 women the same age without breast cancer. They found breast densityContinue reading “Dense breasts may be leading risk factor for breast cancer”
PAX6 expression is essential for corneal epithelial cells
CiRA researchers show PAX6 expression is essential for corneal epithelial cells.The ability of a cell to preserve its identity is crucial for healthy function. When essential transcription factors dysfunction, proper regulation of gene expression is lost, potentially leading to degeneration and disease. Although the cornea is exclusively expressed in the eye, transcription factors that preserveContinue reading “PAX6 expression is essential for corneal epithelial cells”