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Study reveals effects on body mass index of gene linked to heavy smoking

A genetic variant which causes smokers to smoke more heavily has been shown to be associated with increased body mass index (BMI) – but only in those who have never smoked, according to new research. It is likely that this finding has not come to light before because it has been masked by the effect of smoking, which acts to reduce BMI.

Researchers at University of Bristol, working with collaborators including IGMM researchers Archie Campbell, Riccardo Marioni and Caroline Hayward, studied a variant in the CHRNA5-A3-B4 gene cluster which is known to increase smoking heaviness.

They found that the variant is associated with lower BMI in current smokers, but higher in people who have never smoked.  This difference in effects suggests that the variant influences BMI in opposite directions – via  pathways other than smoking for those who have never smoked and by increasing the weight-reducing effects of smoking in those who smoke.

Published by connie dello buono

Connie Dello Buono is based in Sunnyvale California. Her first ebook is about women's health, Birthing Ways Healing Ways and her recent one is about cancer prevention, Curated Healing Ways. She had helped women have holistic childbirth as childbirth educator, founded Motherhealth, to serve seniors in the bay area with holistic caregivers and blogs at www.clubalthea.com with more than 10,000 health and finance related posts. Connie trains her own caregivers, which are the favorites of most bay area seniors who are home bound and alone. She is active in the rehab and nursing facilities, volunteering on music and movement for seniors. She is a member of Lion's club and offered scholarships to students in the Philippines. She is active at churchinsunnyvale.us and has Fridays Bible home study in Sunnyvale using the recovery version of the Bible , free at biblesforamerica.us She loves dancing and teaching and her courses can be found at https://teachclub.com/@thriveafter60 She is California Life Insurance licensed providing life insurance for older adults with health issues and helping women retire safely with income for life. at menloassetca.com , she helps with 401k rollover. 3 Benefit plans - Mortgage protection using term life insurance to pay for mortgage balance in event of death - Final Expense plan using Single Issue Whole Life Insurance, with cash back, disability benefit and guaranteed in the presence of health issues - Fixed Index Annuity retirement plan for safe, accessibility, less fees, less taxes, avoids probate as it goes directly to beneficiaries, rate of return with no downside market participation. She brings compassion and understanding to the needs of her clients, bringing holistic approach in health and life insurance. Her goal is to free families from worries especially during covid with caregivers and life insurance in the presence of health issues, especially for women. She can be reached at 408-854-1883 , motherhealth@gmail.com

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