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First structural map of cystic fibrosis protein sheds light on how mutations cause disease

  When the researchers plotted the locations of mutations (spheres) within the cystic fibrosis protein, they found that many are clustered at a vulnerable joint (lower right). Credit: Laboratory of Membrane Biology and Biophysics at The Rockefeller University/Cell Rockefeller scientists have created the first three-dimensional map of the protein responsible for cystic fibrosis, an inheritedContinue reading “First structural map of cystic fibrosis protein sheds light on how mutations cause disease”