Food and drug interactions Table 1: Food and Drug Interactions Use Interactions/ Guidelines Examples1 ALLERGIES Antihistamine To relieve or prevent the symptoms of colds, hay fever and allergies. FOOD: Take without regard to food. Exception: Fexofenadine/ALLEGRA. Bioavailability decreases if taken with apple, orange, or grapefruit juice. ALCOHOL: Avoid alcohol because it increases the sedative effectsContinue reading “Food and Drug Interactions”