Acetylcysteine serves as a prodrug to L-cysteine. L-cysteine is a precursor to the biologic antioxidant glutathione. Hence administration of acetylcysteine replenishes glutathione stores.[60] – Glutathione, along with oxidized glutathione (GSSG) and S-nitrosoglutathione (GSNO), have been found to bind to the glutamate recognition site of the NMDA and AMPA receptors (via their γ-glutamyl moieties), and mayContinue reading “N-Acetyl Cysteine and Parkinsons”
Category Archives: parkinson’s disease
Quercetin, not caffeine, is a major neuroprotective component in coffee
Quercetin food sources Elderberries Apples Peppers Red wine Dark cherries and berries (blueberries, bilberries, blackberries and others) Tomatoes Cruciferous veggies, including broccoli, cabbage and sprouts Leafy green veggies, including spinach, kale Citrus fruits Title: Quercetin, not caffeine, is a major neuroprotective component in coffee. Authors: Lee M, McGeer EG, McGeer PL. Journal: Neurobiol Aging. 2016Continue reading “Quercetin, not caffeine, is a major neuroprotective component in coffee”
Saliva Gland Test Can Spot Early Parkinson’s Disease
Researchers from Mayo Clinic in Arizona and Banner Sun Health Research Institute have determined that testing a portion of a person’s submandibular gland may be a way to diagnose early Parkinson’s disease. The study was published this month in Movement Disorders, the official journal of the International Parkinson and Movement Disorders Society. Currently, there isContinue reading “Saliva Gland Test Can Spot Early Parkinson’s Disease”
How Neurons Decline as Parkinsons Develops
Electrical activity dwindles in cells long before movement issues become visible. It’s an unsettling thought: You could be walking around for 20 years developing Parkinson’s disease and not even know it. And once symptoms appear, it’s too late for a cure. What if a therapy that treats the root causes of Parkinson’s, not just theContinue reading “How Neurons Decline as Parkinsons Develops”
Effect of Laxatives Could Provide New Clues About Parkinson’s
Summary: Researchers report the rigidity found in Parkinson’s flattens off with regular use of laxatives to help manage constipation. Source: Wiley. In a recent retrospective analysis, investigators discovered that the year-on-year increase in rigidity found in Parkinson’s disease flattened off with the regular use of laxatives to manage constipation. The findings lend support to theContinue reading “Effect of Laxatives Could Provide New Clues About Parkinson’s”
A Protective Strategy Against Pesticide Linked Parkinson’s Disease
Summary: A new study sheds light on how ziram causes the loss of the main source of dopamine in the central nervous system. Source: UCLA. Exposure to a group of common pesticides, called dithiocarbamates, has long been associated with an increased risk of Parkinson’s disease, although the mechanism by which the compounds exert their toxicityContinue reading “A Protective Strategy Against Pesticide Linked Parkinson’s Disease”
Indicators of Parkinson’s Found in Unexpected Places
Summary: Genetic changes associated with Parkinson’s disease have been found in liver, fat, immune and developmental cells, a new study reports. Source: Van Andel Research Institute. Clues that point toward new risk mechanisms for developing Parkinson’s disease are hiding in some unusual spots, according to a study published today in Scientific Reports. Tiny changes inContinue reading “Indicators of Parkinson’s Found in Unexpected Places”
Parkinson and Exercises
Parkinson’s Disease and Exercises Dancing with music is the best exercise followed by Tai Chi. When lying on the bed, use the ROM exercise given by Physical therapists for bed-ridden clients. Pilates stretches your body and practice stretching as you wake up the morning. Call Connie for bay area caregivers at 408-854-1883 for 24-hr responseContinue reading “Parkinson and Exercises”
Dogfish shark steroid could help to prevent the build up parkinson’s
Summary: A synthesised steroid similar to that naturally made by the dogfish shark could help to prevent the build up of alpha synuclein. Source: GUMC. A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying anContinue reading “Dogfish shark steroid could help to prevent the build up parkinson’s”
Parkinson’s Protein Travels From Brain to Gut
Summary: Researchers report alpha-synuclein, a protein associated with Parkinson’s disease, can travel from the brain to the gut by following a specific path. Source: DZNE. A new laboratory study provides clues on a particular pathway of ‘alpha-synuclein’ diffusion. Researchers of the German Center for Neurodegenerative Diseases (DZNE) have found that “alpha-synuclein”, a protein involved inContinue reading “Parkinson’s Protein Travels From Brain to Gut”
Protection Against Parkinson’s Disease May Begin in the Gut
Summary: Researchers report cells located in the gut spark an immune response that protects neurons against damage connected to Parkinson’s. Source: University of Iowa. Your gut may play a pivotal role in preventing the onset of Parkinson’s disease. And the reason may be its knack for sleuthing. Researchers at the University of Iowa have foundContinue reading “Protection Against Parkinson’s Disease May Begin in the Gut”
Researchers Uncover a New Disruption at the Root of Parkinson’s
Summary: Researchers have discovered a genetic mutation that causes Parkinson’s can prevent synapses from coping with the stress of intense brain activity. Source: VIB Flanders. Leading-edge research by the team of professor Patrik Verstreken (VIB-KU Leuven) has shown for the first time that a malfunctioning stress-coping mechanism in the brain is at the root ofContinue reading “Researchers Uncover a New Disruption at the Root of Parkinson’s”
Single Mutation in Recessive Gene Increases Risk of Earlier Onset Parkinson’s Disease
Summary: Researchers have discovered a genetic mutation that could signify a risk for early onset of Parkinson’s disease. Source: Mayo Clinic. A collaboration of 32 researchers in seven countries, led by scientists at Mayo Clinic’s campus in Florida, has found a genetic mutation they say confers a risk for development of Parkinson’s disease earlier thanContinue reading “Single Mutation in Recessive Gene Increases Risk of Earlier Onset Parkinson’s Disease”
People With Parkinson’s Show Altered Iron Levels in Their Brains
Summary: A new neuroimaging study finds iron is distributed in an unusual way in the brains of people with Parkinson’s disease. Source: DZNE. A special type of brain mapping reveals pathological alterations that conventional neuroimaging is unable to track. Iron occurs naturally in the human body. However, in people with Parkinson’s disease it distributes inContinue reading “People With Parkinson’s Show Altered Iron Levels in Their Brains”