Long-term use of proton pump inhibitors is associated with increased microbial product translocation, innate immune activation, and reduced immunologic recovery in patients with chronic HIV-1 infection DOI: https://doi.org/10.1093/cid/cix609 Abstract Background: Translocation of microbial products from the damaged gut causes increased immune activation in HIV. Proton pump inhibitors (PPIs) predispose to bacterial overgrowth in the gut.Continue reading “Long-term use of proton pump inhibitors is associated with increased microbial product translocation, innate immune activation, and reduced immunologic recovery in patients with chronic HIV-1 infection”