Summary: A new study reports women with diabetes were 3 times more likely to have anti-fetal autoantibodies, especially those whose children’s autism fell on the severe end of the spectrum. Source: UC Davis. Diabetic women were 3 times more likely to have anti-fetal brain autoantibodies, particularly those whose children’s autism fell on the severe endContinue reading “Mothers With Diabetes More Likely to Have Anti-Fetal Brain Autoantibodies”
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Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends
A group of scientists at the Chinese University of Hong Kong explored the limit of noninvasive prenatal testing by performing genome-wide sequencing of maternal plasma DNA at 195× and 270× haploid genome coverages. Combined with the use of a series of bioinformatics filters, fetal de novo mutations could be detected with a positive predictive value thatContinue reading “Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends”