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Half of hospital death is by Sepsis

The baby seemed fine when Dr. Thomas R. Frieden left for work that July morning in New York more than 20 years ago. But when he returned home several hours later, his son was pale and blazing hot, limp in his wife’s arms.

“My first thought was that he was dead,” said Dr. Frieden, now the director of the Centers for Disease Control and Prevention. “It was so scary, even for someone trained as a physician, to see how quickly someone who’s healthy can become critically ill.”

Dr. Frieden, an infectious diseases specialist, knew time was of the essence. His hunch, which turned out to be correct, was that his son had developedsepsis, a life-threatening condition triggered by an infection that can very quickly spiral out of control.

He called the child’s pediatrician, and within hours, the infant had received a broad-spectrum antibiotic. He recovered within a few days.

Many patients are not so fortunate. Between one million and three million Americans are given diagnoses of sepsis each year, and 15 percent to 30 percent of them will die, Dr. Frieden said. Sepsis most commonly affects people over 65, but children are also susceptible. According to one estimate, more than 42,000 children develop sepsis in the United States every year, and 4,400 die.

Sepsis develops when the body mounts an overwhelming attack against an infection that can cause inflammation in the entire body. When that happens, the body undergoes a cascade of changes, including blood clots and leaky blood vessels that impede blood flow to organs. Blood pressuredrops, multiple organs can fail, the heart is affected, and death can result.

“Your body has an army to fight infections,” said Dr. Jim O’Brien, the chairman of Sepsis Alliance. “With sepsis, your body starts suffering from friendly fire.”

Sepsis appears to be rising. The rate of hospitalizations that listed sepsis as the primary illness more than doubled between 2000 and 2008, according to a 2011 C.D.C. study, which attributed the increase to factors like the aging of the population, a rise in antibiotic resistance and, to some extent, better diagnosis.

Sepsis is a contributing factor in up to half of all hospital deaths, but it’s often not listed as the cause of death because it often develops as a complication of another serious underlying disease like cancer. So although death certificates list sepsis as a cause in 146,000 to 159,000 deaths a year, a recent report estimated that it could play a role in as many as 381,000.

Yet advocacy organizations say many Americans have never heard of sepsis and don’t know the signs and symptoms.

Photo

Dr. Thomas Frieden, director for the Centers for Disease Control and Prevention, wants sepsis to become a household word to get at-risk patients medical treatment sooner.CreditKevin D. Liles for The New York Times

Ciaran and Orlaith Staunton, a Queens couple who lost their son Rory, a sixth-grader, to sepsis in 2012, discovered the condition was not even listed on the A to Z index of the C.D.C.’s website at the time. They met with Dr. Frieden and urged him to use his bully pulpit to educate Americans about the disease.

Now the C.D.C. is starting a major public awareness campaign to make sepsis a household word. The first step is to teach people to seek treatment quickly when a loved one begins to show symptoms of sepsis, which include chills or fever; extreme pain or discomfort; clammy or sweaty skin; confusion or disorientation; shortness of breath; and a high heart rate.

The campaign, which has developed educational fact sheets, encourages lay people to suggest the diagnosis to health care providers who may overlook it. Ask the doctor, “Could it be sepsis?” or say, “I’m worried about sepsis.”

“We want people to be able to recognize sepsis just like they recognize a heart attack or stroke, and know they shouldn’t wait until Thursday when the doctor can see them, but go to the emergency room right away,” said Thomas Heymann, executive director of Sepsis Alliance. The group’s motto is, “Suspect sepsis, save lives.”

When blood pressure drops and chokes blood flow to the body’s organs, a person can develop septic shock. For every hour without antibiotics, the probability of dying goes up by 8 percent, Dr. O’Brien said.

While earlier initiatives have focused on reducing sepsis deaths that developed in hospitals, newer studies suggest most cases start in the community setting, before people are hospitalized. The new campaign was spurred in part by the latest C.D.C. study, which examined the hospital records of 246 adults and 79 children, finding that in nearly 80 percent of cases, sepsis had started when the patient was at home.

The study also shed light on who is most susceptible to sepsis. Though it occurs most often in people over 65, infants under the age of 1 are also susceptible, as are people with chronic diseases like diabetes or immune systems weakened from tobacco use, for example. And healthy people can develop sepsis from an infection that’s not treated properly as well.

The Stauntons’ son died after developing an infection that wasn’t recognized by emergency room doctors who examined him at NYU Langone Medical Center. A new state law passed after his death requires hospitals in New York to screen all patients for sepsis in order to start treatment early.

The new C.D.C. study found sepsis is most often associated with lung, urinary tract, skin and gut or intestinal infections, and that many sepsis patients had visited a doctor or been in a health care setting before developing the infection.

The C.D.C. is aiming efforts at health care providers, urging them to consider sepsis and act quickly, and investing in research to study risk factors. It is also emphasizing prevention through better management of chronic diseases, vaccinations and appropriate use of antibiotics.

Food drop on the floor can be contaminated by bacteria instantly

Research by the Centers for Disease Control, which found that surface cross-contamination was the sixth most common contributing factor out of 32 in outbreaks of food-borne illnesses.

How was the study conducted?

Professor Schaffner and a master’s thesis student, Robyn C. Miranda, tested four surfaces — stainless steel, ceramic tile, wood and carpet — and four different foods: cut watermelon, bread, buttered bread and strawberry gummy candy. They were dropped from a height of five inches onto surfaces treated with a bacterium with characteristics similar to salmonella.

The researchers tested four contact times — less than one second and five, 30 and 300 seconds. A total of 128 possible combinations of surface, food and seconds were replicated 20 times each, yielding 2,560 measurements.

What did the study find?

The research found that the five-second rule has some validity in that longer contact times resulted in transfer of more bacteria. But no fallen food escaped contamination completely. “Bacteria can contaminate instantaneously,” Professor Schaffner said in a news release.

Carpet had a very low rate of transmission of bacteria compared with tile and stainless steel; transfer rates from wood varied.

Blood pressure drug for Malaria

Giving malaria victims a common blood-pressure drug along with regular treatment may save lives by preventing lethal brain hemorrhages, scientists reported on Monday.

The experiments were done only in infected mice and may not predict success in humans. But substantially more mice were saved when given the drug, according to scientists at NYU Langone Medical Center and their colleagues in Spain and Germany.

The study was published in The Journal of Clinical Investigation.

There are an estimated 216 million malaria infections around the world each year, and more than 400,000 deaths — mostly young children in Africa. Most of the fatalities, the authors said, were caused by cerebral malaria.

Parasite-filled red blood cells become “sticky” and clump together in the brain’s tiny capillaries, first jamming them and then weakening their walls so that blood leaks through.

A fifth of those patients reach hospitals but die within 48 hours, the time it takes for parasite-killing drugs to work, said Ana Rodriguez, a parasitologist at NYU Langone and a study author.

A drug that stopped hemorrhages during that window “would buy time so they don’t die in the meanwhile, and save lives,” she said.

In the study, 82 percent of mice with cerebral malaria that were treated just with parasite-killing chloroquine died, compared with only 35 percent of those treated with chloroquine combined with irbesartan, a blood-pressure drug.

Irbesartan is sold as Avapro in the United States, where it costs about $4.50 per pill. But generic versions are made in India for as little as 11 cents per pill, and a malaria patient would need only a few, Dr. Rodriguez said.

Treat your teeth and gums well

To Learn More about Holistic Dentistry (aka Biological or Environmental Dentistry), please visit Dr. Garcia’s Dental Corner.

1. You should first floss your teeth regularly. Ideally it should be after every meal. The best floss would be the non waxed type.

2. Then you can use a dry Periodontal Health Brush (715-597-3935, I also have them in my office). Blot the brush at a 45 degree angle at the gum line about 20 times in each area around the mouth. Start behind the teeth first. You can rinse or snap dry the brush after each area to remove the bacteria and parasites.

3. You can keep your toothbrush clean by soaking it in a capful of hydrogen peroxide once a week. This is more than sufficient to kill the bacteria that normally accumulate in the brush.

4. Next, it would be helpful to use a Water Pik to remove any food particles that you might have missed with the above cleaning. This should also remove the bulk of the bacteria present on the surface of the gums and margins next to the teeth.

5 This step is one of the most important. Do NOT use regular toothpaste. Most of it has fluoride which clearly is a poison and not intended for human use. Instead use a mixture of six parts of baking soda to one part of Real Salt or Sea Salt. Place them in a blender and mix for 30 seconds then place in a container to use.

6. Wet the tip of your index finger and place a SMALL amount of the salt and soda mixture on the gums. Starting with the upper outside gums and then the inside of the upper, followed by the lower outside of the gums then the lower inside. Spit out the excess. After 15 minutes rinse your mouth. This mixture is incredibly effective at killing the bacteria and parasites that cause plaque. It is very important to improve periodontal health. Some dentist will even take a sample from your mouth and show you with a microscope the incredible difference prior to and after using this program and how it radically reduce the bacterial concentration in your gums. And healthy gums means less dental decay, a healthier body and less dental bills.


Connie’s comments: You can also mix your own mouth wash using hydrogen peroxide, 3% and water.

Mobile health application for all doctors and cancer families

Story

When my father died of lung cancer, I vowed to empower other families in their plight against cancer thru my blog. Now, I want to reach more communities with a mobile health application that is tailored per community and bringing telemedicine to everyone and include curated health information and community building/support.

page-1-mobile-health-application-careme-live

Your feedback

Please email motherhealth@gmail.com about what you want in a mobile health application if you are a doctor, a family member taking care of a senior with chronic health issues or a health promotion professional who is passionate about empowering others to have the support they need when they have health issues.

The mobile health application

Our health application at Motherhealth can do telemedicine (video chat with doctors, match care providers with patients such as caregivers/dentists/others), monitor patient generated health data (cancer risk factors formula,share patient data to doctors, create reporting analytics, and other curated health info and search for health communities (activities, health buddies,senior day care,etc).

Goal: Reduce chronic care costs, to do more monitoring at home for chronic diseases.
Market/Audience:

  1. Doctors who are not using telemedicine yet
  2. Care providers (caregivers/genetic counselors) who wanted to reach out to clients without a video chat function
  3. Cancer/Alzheimer’s families to monitor health data
  4. Match health promoting activities within the community, exercise lessons for Parkinsons, health coaching, sharing stories, and more
  5. Reporting analytics: global, health data insights for cancer, chronic disease and more

We are seeking mobile developers and investors to join us bring this health solution to all.

Connie Dello Buono
CEO
Motherhealth LLC
1708 Hallmark Lane , San Jose, CA 95124
http://www.motherhealth.net
http://www.careme.live
motherhealth@gmail.com

indie

https://www.indiegogo.com/projects/cancer-riskfactor-and-doctor-video-chat-mobile-app-medicine/x/3335495#/

 

Calorie Calculator

calorie-calc

http://www.bodybuilding.com/fun/the-6-principles-of-getting-lean.html

Connie’s comments:

  • Your food choices should include whole foods and raw foods with this ratio: 40% Protein, 30% carbs and 30% fat.
  • You can still eat meals prepared based on your cultural practise but add exercise in your routine and avoid sugar, exposure to smoking, excessive alcohol and avoid processed foods.

Women:

  • Women can increase their calories from fat (35%) and reduce carbs (25%) to create a balance.
  • Eat heavy meal 3-4hrs before bedtime. 9pm bedtime would mean that dinner is at around 6pm.
  • Normal sleep pattern for women based on their hormones is between 9pm to 5am.

Strive to eat plant-based diets (although they have low content of Leucine, Methaionine, Arganine) to live longer:

  • Glycotoxins
  • One in a Thousand: Ending the Heart Disease Epidemic
  • Food Antioxidants, Stroke, Cancer and Heart Disease
  • Nuts May Help Prevent Death
  • Increased Lifespan From Beans

 

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