Two types of people
- Tightly coupled: Only needs to eat less to arrive at required energy level
- Loosely coupled: Needs to eat more to arrive at required energy level
Sun energy and glucose for energy production
Nucleus is energy limited
Mitochondrial DNA crosstalk: 10% changes in mtDNA has a greater effect in epigenetic expression
Haplogroup U and H
Male bias mito DNA unique
mtDNA background variation
Human migration and Mitochondrial DNA Variation
Selective mutation by Altitude
Phenotypes of mitochondrial DNA depends on Context
Background and context are both important in mitochondrial DNA mutation
Nucleus normal, Parkinson type mutation , this is an Energetic Disease
Reactive Oxygen Species Toxicity
Nutrition and Stress in Hypoactive Heteroplasmic Species, Learning Disability
