Benign prostatic hyperplasia (BPH) and associated lower urinary tract symptoms (LUTS) are common clinical problems in urology. While the precise molecular etiology remains unclear, sex steroids have been implicated in the development and maintenance of BPH. Sufficient data exists linking androgens and androgen receptor pathways to BPH and use of androgen reducing compounds, such asContinue reading “Benign prostatic hyperplasia (BPH), estrogen and phytoestrogens”
Tag Archives: endocrine disrupting substances
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Genetics of infertility, zinc, pituitary gland and Endocrine disruptors
About 10–15% of human couples are infertile, unable to conceive. In approximately in half of these cases, the underlying cause is related to the male. The underlying causative factors in the male infertility can be attributed to environmental toxins, systemic disorders such as, hypothalamic–pituitary disease, testicular cancers and germ-cell aplasia. Genetic factors including aneuploidies andContinue reading “Genetics of infertility, zinc, pituitary gland and Endocrine disruptors”