Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome

Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome (PCOS). A randomized controlled trial

Abstract

Hirsutism in polycystic ovarian syndrome (PCOS), consequent to elevated androgen levels leads to significant cosmetic and psychological problems. Recent research in Turkey has shown that spearmint tea has antiandrogenic properties in females with hirsutism. No research has yet been undertaken to assess whether a reduction in androgen levels brought about by spearmint tea, translates to a clinical improvement in the degree of hirsutism.

This study was a two centre, 30 day randomized controlled trial. Forty two volunteers were randomized to take spearmint tea twice a day for a 1 month period and compared with a placebo herbal tea.

At 0, 15 and 30 days of the study serum androgen hormone levels and gonadotrophins were checked, the degree of hirsutism was clinically rated using the Ferriman-Galwey score and a questionnaire (the modified DQLI = Dermatology Quality of Life Index) was used to assess improvements in the level of self-reported hirsutism. Forty one of 42 patients completed the study.

Free and total testosterone levels were significantly reduced over the 30 day period in the spearmint tea group (p < 0.05). LH and FSH also increased (p < 0.05). Patient’s subjective assessments of their degree of hirsutism scored by the modified DQLI were significantly reduced in the spearmint tea group (p < 0.05). There was, however, no significant reduction in the objective Ferriman-Galwey ratings of hirsutism between the two trial groups over the trial duration (p = 0.12). There was a clear and significant alteration in the relevant hormone levels.

This is associated clinically with a reduction in the self-reported degree of hirsutism but unfortunately not with the objectively rated score. It was demonstrated and confirmed that spearmint has antiandrogen properties, the simple fact that this does not clearly translate into clinical practice is due to the relationship between androgen hormones and follicular hair growth and cell turnover time.

Simply put, the study duration was not long enough. The original studies from Turkey were in fact only 5 days long. The time taken for hirsutism to resolve is significant and a much longer future study is proposed as the preliminary findings are encouraging that spearmint has the potential for use as a helpful and natural treatment for hirsutism in PCOS.

What is the best diet for a woman suffering from PCOS?

Connie b. Dellobuono
Connie b. Dellobuono, Health author and blogger at http://www.clubalthea.com

Women must help protect the brain from the negative effects of cortisol and other stress hormones.

Polycystic ovary syndrome (PCOS) is a complex hormonal disorder and … one of them — that are produced in the ovary and the adrenal gland.

Reasons for adrenal fatigue and dysfunction:

Emotional stress, typically related to grief or loss

Poor diet: Eating too many carbs can disrupt cortisol and a certain group of corticosteroids (a blood pressure-stabilizing hormone), and the Standard American Diet is “a perfect recipe for destroying your adrenal glands,” Dr. Kalish warns.

One of the most important things that cortisol does is regulating secretory IgA in your gut. What this means is that the immune response in your gut is controlled by cortisol. Hence, if you’re stressed, the immune response in your gut suffers, the gut tissue becomes damaged, and good bacteria give way to bad bacteria, causing immune dysregulation that is centered in and around your gut.

Two important components to address this problem are to:

  • regularly eat fermented foods, which will dramatically increase the beneficial bacteria in your body (which automatically will help decrease pathogenic bacteria), and
  • to eat a diet low in sugars and carbs, as that will also promote a healthy gut flora.
  • High magnesium foods :
    include dark leafy greens, nuts, seeds, fish, beans, whole grains, avocados, yogurt, bananas, dried fruit, dark chocolate, and more. The current daily value (DV) for magnesium is 400mg.
    Senior care and Disease Prediction search for Magnesium
  • Probiotic
  • Ketogenic diet to nourish the brain . See Ketogenic diet for mental health issues
  • Anti-stress diet
    • Green Leafy Vegetables. Dark leafy greens like spinach are rich in folate, which helps your body produce mood-regulating neurotransmitters, including serotonin and dopamine. …
    • Organic Turkey Breast. …
    • Fermented Foods. …
    • Wild-Caught Alaskan Salmon. …
    • Blueberries. …
    • Pistachios. …
    • Dark Chocolate. …
    • Sunshine.
    • Exercise , 30 min a day and sunshine – Vitamin D

Top 10 Niacin Rich Foods – Eat all Vitamin B rich food sources

  • Turkey. 1 breast: 101 mg (over 100% DV)
  • Chicken breast (organic hormone free). 3 oz: 8.9 mg (44% DV)
  • Peanuts. 1 cup: 21.9 mg (over 100% DV)
  • Mushrooms. 1 cup: 7.6 mg (34% DV)
  • Liver. 1 slice: 11.9 mg (60% DV)
  • Tuna. 3 oz: 11.3 mg (56% DV)
  • Green peas. 1 cup: 3 mg (15% DV)
  • Grass-fed Beef
  • Seaweed
    Dietary Fiber, Vitamin C, Pantothenic Acid, Zinc and Copper, and a very good source of Vitamin K, Riboflavin, Folate, Calcium, Iron, Magnesium and Manganese.
  • Many foods are excellent sources of folate—fruits and vegetables, whole grains, beans, breakfast cereals, and fortified grains and grain products. It’s best to avoid foods that are heavily fortified with folic acid.
  • Top 10 Foods High in Selenium
  • Brazil nuts. 1 oz (6-8 nuts): 544 mcg (over 100% DV)
  • Yellowfin tuna. 3 oz: 92 mcg (over 100% DV)
  • Halibut, cooked. 3 oz: 47mcg (67% DV)
  • Sardines, canned. 3 oz: 45mcg (64% DV)
  • Grass-fed beef. 3 oz: 33 mcg (47% DV)
  • Turkey, boneless. 3 oz: 31 mcg (44% DV)
  • Beef liver
  • Chicken
  • Chillies or hot pepper
  • Beef broth or bone marrow soup with veggies
  • Cinnamon
    One tablespoon of ground cinnamon contains: 19 calories. 0 grams of fat, sugar, or protein. 4 grams of fiber. 68% manganese. 8% calcium. 4% iron. 3% Vitamin K.
  • Ginger and garlic family : Sulfur Containing Foods
    • Arugula
    • Coconut milk, juice, oil
    • Cruciferous veggies, including: bok choy, broccoli, cabbage, cauliflower, horseradish, kale, kohlrabi, mustard leaves, radish, turnips, watercress.
    • Dairy (except butter)
    • Dried fruits
    • Eggs
    • Garlic
    • Legumes and dried beans
  • See Senior care and Disease Prediction – search for anti aging food diet
  • Tip for produce: Wash veggies with salt water or diluted vinegar.

Can hirsutism get reduced over time?

Can hirsutism get reduced over time? by Connie b. Dellobuono

Answer by Connie b. Dellobuono:

See a doctor. I would avoid estrogen rich food and eat more progesterone rich food. There is cell energy herbal caps at http://www.getwellinternational.com that removes excess estrogen.
From Wiki:
Hirsutism can be caused by either an increased level of androgens, the male hormones, or an oversensitivity of hair follicles to androgens. Male hormones such as testosterone stimulate hair growth, increase size and intensify the growth and pigmentation of hair. Other symptoms associated with a high level of male hormones include acne, deepening of the voice, and increased muscle mass.
Growing evidence implicates high circulating levels of insulin in women for the development of hirsutism. This theory is speculated to be consistent with the observation that obese (and thus presumably insulin resistant hyperinsulinemic) women are at high risk of becoming hirsute. Further, treatments that lower insulin levels will lead to a reduction in hirsutism.
It is speculated that insulin, at high enough concentration, stimulates the ovarian theca cells to produce androgens. There may also be an effect of high levels of insulin to activate insulin-like growth factor 1 (IGF-1) receptor in those same cells. Again, the result is increased androgen production.
Signs that are suggestive of an androgen-secreting tumor in a patient with hirsutism is rapid onset, virilization and palpable abdominal mass.
The following may be some of the conditions that may increase a woman’s normally low level of male hormones:
Adrenal gland cancer, Von Hippel–Lindau disease.
Congenital adrenal hyperplasia, in turn mostly caused by 21-α hydroxylase deficiency.
Cushing’s disease.
Growth hormone excess (acromegaly).
Insulin resistance.
Obesity: As there is peripheral conversion of androgens to estrogen in these patients, this is the same mechanism as polycystic ovary syndrome, PCOS.
Polycystic ovary syndrome (PCOS), the most common cause in ciswomen.
Porphyria cutanea tarda.
Stromal hyperthecosis (SH) – in postmenopausal women.
Transsexualism (male birth sex)
Tumors in the ovaries .
Use of certain medications such as tetrahydrogestrinone, phenytoin, or minoxidil.
—-
Dr Mercola wrote about PCOS: You can’t just take progesterone, and you can’t just cut out the sugar. You usually need to do both. Exercise and good nutrition are also very important in maintaining hormone balance.
——
Do avoid plastics and chemicals that alter our hormonal balance. Do a liver detox. Eat more cilantro and sulfur rich foods.

Can hirsutisum get reduced over time?