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Could a Protein Called Klotho Block Dementia and Aging?

To bring this boost in brain health to everyone, and not just the 20 percent of people who happen to have naturally high klotho, Dubal is testing the protein’s potential as a therapeutic.

The protein can exist in two forms: the first is anchored to the cell membranes of your organs, mostly your brain and kidneys; and the second occurs when the protein is cut loose from its anchor and freed to float around the bloodstream.

Klotho enzyme , calcium, insulin , Vitamin D and Alzheimer

Klotho is an enzyme that in humans is encoded by the KL gene.[5] This gene encodes a type-I membrane protein that is related to β-glucuronidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen inContinue reading “Klotho enzyme , calcium, insulin , Vitamin D and Alzheimer”