Acute myocardial infarction is characterized by changes in biochemical properties during ischemia and reperfusion. The heart can survive a short period of ischemia by reducing myocardial contractility, increasing glucose uptake, and switching metabolism to glycolysis. However, considering that the heart is one of the most energy-demanding tissues in the body, sustained oxygen and nutrient deprivationContinue reading “Acute myocardial infarction; imbalance during ischemia-reperfusion ; mitochondrial energy adaption in cancer, obesity and metabolic disorders”
Tag Archives: obesity
Starvation, diet-induced obesity (unhealthy snacks) elevated triglycerides, decreased transport of leptin to brain lead to obesity
Obesity is associated with leptin resistance as evidenced by hyperleptinemia. Resistance arises from impaired leptin transport across the blood-brain barrier (BBB), defects in leptin receptor signaling, and blockades in downstream neuronal circuitries. The mediator of this resistance is unknown. Here, we show that milk, for which fats are 98% triglycerides, immediately inhibited leptin transport asContinue reading “Starvation, diet-induced obesity (unhealthy snacks) elevated triglycerides, decreased transport of leptin to brain lead to obesity”
Metabolic Syndrome and Obesity in Men and Women
Males are most likely to meet the criteria for metabolic syndrome: prothrombotic state, proinflammatory state, insulin resistance, raised blood pressure, atherogenic dyslipidemia and abdominal obesity. ————————————- Aside from feeding your brain, use your memory. Use your brain or lose it. Learn new skills. If today’s jobs are either in computers or medical, learn new skills.Continue reading “Metabolic Syndrome and Obesity in Men and Women”