Blood–brain barrier (BBB) pathways to neurodegeneration in dementia and Alzheimer’s disease (AD) A: In the normal capillary, there is an intact BBB composed of tightly joined endothelial cells and supported by mural pericytes, as shown in this simplified schematic. The BBB normally selectively regulates the passage of molecules from blood to brain and vice versa,Continue reading “Damage to Blood–brain barrier (BBB) pathways leading to Alzheimer’s disease and Dementia”