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Middle age inflammation linked to brain shrinkage decades later

According to a new study, people who have inflammation biomarkers in their blood during middle age are more likely to have increased brain shrinkage as they grow older. Researchers report the brain cell loss associated with inflammation was most prevalent in areas affected in Alzheimer’s disease

Enzyme drives middle-age weight and fitness changes

Scientists identified an enzyme in animal studies whose activity promotes weight gain and the loss of exercise capacity starting in mid-life. A drug that inhibits the enzyme prevented weight gain in mice, increased fitness levels, and reduced the incidence of obesity and type 2 diabetes. The findings could lead to more effective weight-loss medications. DNA-PKContinue reading “Enzyme drives middle-age weight and fitness changes”