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Affordable in home care | starts at $28 per hr

You need 24/7 caregiver to be discharged in the hospital or rehab, call 4088541883

When your case manager evaluated that your parents need 24/7 and need to meet with the caregivers to be discharged, text or call 408-854-1883

Motherhealth LLC will match your caregiving needs.

We serve the bay area and nearby cities. Peninsula, San Francisco, San Mateo, Santa Clara, Alameda, Contra Costa and nearby cities.

We treat clients like family. For each client, we have 3 caregivers and a case manager to train and monitor each caregiver and be involved in the care of each client. We believe in whole foods, hugs and massage. Our services include assistance in daily living, light housekeeping and more.

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From CNA to Home Health Care Aid to LVN to RN

To start your Certified Nursing Assistant (CNA) career this January, attend this Friday orientation at:

http://www.mvla.net/MVLA_Adult_Education/

CNA costs $600 and $130 to be Home health care aid certified (attend 2 week class, evening or morning) and challenge the LVN and attend online a nursing program.

Motherhealth LLC will reimburse you after your first month as caregiver. Motherhealth LLC will conduct review classes for the LVN program. Connie Dello Buono was former Pharmacy Technician Instructor. To start working as a caregiver today, text 408-854-1883 or email your references and info at motherhealth@gmail.com

Do get a TB test and register as homecare aid or caregiver at the Dept of Social Services.

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Stem Cell Roundup: Crafty Cancer, Fighting Viruses, and Brainstorm ALS Trial Expands to Canada

Researchers at Duke University were studying lung tumor samples and discovered something that didn’t quite belong. Inside the lung tumors were miniature parts of the digestive system including the stomach, duodenum and small intestine. It turns out that the lung cancer cells (and cancer cells in general) are super crafty and had turned off the expression of a gene called NKX2-1. This gene is a master switch that tells developing cells to turn into lung cells. Without this command, cells switch their identity and mature into gut tissue instead. By manipulating these master switches, cancer cells are able to develop resistance to chemotherapy and other cancer treatments.

So, what does this bizarre finding mean for cancer research? Purushothama Rao Tata, first author on the Developmental Cell study, provided an answer in a news release:

“Cancer biologists have long suspected that cancer cells could shape shift in order to evade chemotherapy and acquire resistance, but they didn’t know the mechanisms behind such plasticity. Now that we know what we are dealing with in these tumors – we can think ahead to the possible paths these cells might take and design therapies to block them.”

For more cool photos and insights into this study, watch the Duke University video below.

Secrets to the viral-fighting ability of stem cells uncovered (Todd Dubnicoff)

I’ve been writing about stem cells for many years and thought I knew most of the basic info about these amazing cells. But up until this week, I had no idea that stem cells are known to fight off viral infections much better than other cells. It does makes sense though. Stem cells give rise to and help maintain all the organs and tissues of the body. So, it would be bad news if, let’s say, a muscle stem cell multiplied to repair damaged tissue while carrying a dangerous virus.

How exactly stem cells fend off attacking viruses is a question that has eluded researchers for decades. But this week, results published in Cell by Rockefeller University scientists may provide an answer.

The researchers found that liver cells and stem cells defend themselves against viruses differently. In the presence of a virus, liver cells and most other cells react by releasing large amounts of interferon, a protein that acts as a distress signal to other cells in the vicinity. That signal activates hundreds of genes responsible for attracting protective immune cells to the site of infection.

Stem cells, however, are always in this state of emergency. Even in the absence of interferon, the antiviral genes were activated in stem cells. And when the stem cells were genetically engineering to lack some of the antiviral genes, the cells no longer could stop viral infection.

In a press release, senior author Charles Rice explained the importance of this work:

“By understanding more about this biology in stem cells, we may learn more about antiviral mechanisms in general.”

CIRM-funded clinical trial for ALS now available next door – in Canada (Kevin McCormack)

In kindergarten we are taught that it’s good to share. So, we are delighted that a Phase 3 clinical trial for ALS – also known as Lou Gehrig’s disease – that CIRM is helping fund is now expanding its reach across the border from the U.S. into Canada.

Brainstorm Cell Therapeutics, the company behind the therapy, says it is going to open a clinical trial site in Canada because so many Canadians have asked for it.

The therapy, as we described in a recent blog post, takes mesenchymal stem cells from the patient’s own bone marrow. Those cells are then modified in the lab to be able to churn out specific proteins that can help protect the brain cells attacked by ALS. The cells are then transplanted back into the patient and the hope is they will slow down, maybe even stop the progression of the disease.

Earlier studies showed the therapy was safe and seemed to benefit some patients. Now people with ALS across our northern border will get a chance to see if it really works.

Chaim Lebovits, the president and chief executive officer of BrainStorm, said in a press release:

“Although there are thousands of patients worldwide with ALS, we initially designed the Phase 3 trial to enroll U.S.-based patients only, primarily to make it easier for patient follow-up visits at the six U.S. clinical sites. However, due to an outpouring of inquiry and support from Canadian patients wanting to enroll in the trial, we filed an amendment with the FDA [the U.S. Food and Drug Administration] to allow Canada-based ALS patients to participate.”

Epileptics Living in High Crime Areas Have Three Times As Many Seizures

Epileptics Living in High Crime Areas Have Three Times As Many Seizures

Summary: According to a new study, those with epilepsy who live in high crime neighborhoods have three times as many seizures as those living in lower crime areas.

Source: University of Illinois.

People with epilepsy living in high crime neighborhoods in Chicago had three times as many seizures as those living in neighborhoods with lower crime rates according to new research from the University of Illinois at Chicago presented at the American Epilepsy Society 2018 conference in New Orleans.

Epilepsy is a chronic neurological disorder characterized by abnormal brain activity and seizures that affects more than 65 million people worldwide. About one-third have difficulty controlling their seizures even with medication. Seizures can interfere with work, relationships, and the ability to live independently. Previous research has shown that living in neighborhoods with high rates of crime have significantly higher levels of the stress hormone, cortisol. Stress is also a factor that is commonly reported to trigger seizures in people with epilepsy.

The UIC study included 63 adults with epilepsy living within the city limits of Chicago who were participating in a larger study testing the efficacy of a tablet-based educational tool that provides tailored information about epilepsy. That study, called PAUSE, involves patients at the University of Illinois Hospital’s epilepsy clinic and in the Chicagoland community and is facilitated by the Epilepsy Foundation of Greater Chicago.

The researchers determined the levels of crime in neighborhoods of the 63 participants by mapping their zip codes to specific neighborhoods and then cross-referencing those neighborhoods with local crime rates available through the City of Chicago Police data portal. Participants self-reported the number of seizures they had in the past month and in the past three months.

brain

“We found that people living with epilepsy who live in high-crime neighborhoods experienced significantly more seizures,” said Jessica Levy, a research coordinator in the UIC department of neurology and rehabilitation who presented the findings. “On average, people in high-crime neighborhoods had three seizures versus one for people living in low-crime neighborhoods when we looked back over the last 30 days. Over the course of 90 days, people in high-crime neighborhoods had seven seizures on average compared to three for those living in low-crime neighborhoods, so the link between crime and seizure activity is significant.”

The researchers found no overall association between neighborhood crime status and the duration of epilepsy or between crime status and poverty.

Having more seizures can significantly lower quality of life. Seizures that result in falls can cause bruising or even broken bones. There can also be a stigma associated with having a seizure in public.

“Understanding the impact of violence and crime as potential triggers for seizures underscores the need for further research that might allow clinicians to make better-informed recommendations for self-management education and stress management skills,” said Dr. Dilip Pandey, associate professor of neurology and rehabilitation at UIC and an investigator on the study.

ABOUT THIS NEUROSCIENCE RESEARCH ARTICLE

Katharine Ozenberger is a co-investigator on the study.

The PAUSE study is conducted through the UIC department of neurology and rehabilitation by Dr. Dilip Pandey and Dr. Jeffery Loeb.

Funding: PAUSE is supported by the University of Illinois Prevention Research Center and the Centers for Disease Control and Prevention (CDC) Managing Epilepsy Well (MEW) Network under CDC cooperative agreement no. U48-DP005010.

Source: Sharon Parmet – University of Illinois
Publisher: Organized by NeuroscienceNews.com.
Image Source: NeuroscienceNews.com image is in the public domain.
Original Research: The study will be presented at the American Epilepsy Society Meeting.

Boys with Social Difficulties More Susceptible to Early Substance Use

Boys with Social Difficulties More Susceptible to Early Substance Use

Summary: A new study reports boys with social skill problems during sixth grade are more likely to develop substance use issues by grade eight.

Source: University of Illinois.

Boys who enter sixth-grade with co-occurring social skills, anxiety, learning and conduct problems are at the greatest risk of developing aggressive behavior and using tobacco, alcohol and marijuana by the end of eighth grade, a new study found.

“While substance use among all boys in the study population increased over time, it increased the fastest among boys who had the greatest social skills needs,” said University of Illinois social work professor Kevin Tan, the principal investigator of the study.

Rather than any single factor, a combination of characteristics may predict youths’ risk of succumbing to or avoiding problem behaviors, Tan said.

Tan and his co-authors found four distinct patterns of co-occurring social-emotional learning and behavioral problems among the more than 2,600 middle-school boys in their study. The boys were students at 37 schools located in Chicago; Durham, North Carolina; Athens, Georgia; and Richmond, Virginia.

At four time points, beginning in the fall term of sixth grade and ending in the spring term of eighth grade, the students were surveyed on their verbal, relational and physical aggression and their use of cigarettes, alcohol and marijuana during the prior 30 days.

At each time point, a teacher also assessed each boy’s social skills development, symptoms of anxiety and learning problems. Teachers also reported on their students’ conduct, such as how frequently they skipped classes and stole from other students.

Boys who had significant problems in all four domains – social skills, anxiety, learning and conduct – were the most susceptible to engaging in aggression and substance use, the researchers found.

Although this group composed only 6.3 percent of the study population, prior research has shown that youths with these characteristics are at the greatest risk of the poorest outcomes across their lifespans, according to Tan and his co-authors.

Conversely, the researchers found that boys who scored well on social, emotional, learning and conduct – a group that composed more than 61 percent of the sample – showed only small increases in physical aggression and substance use.

The third risk pattern involved boys who had poor social skills in addition to learning and conduct problems. While these boys entered sixth grade exhibiting the most behavioral problems, their physical and relational aggression and cigarette smoking declined over time and their alcohol and marijuana use didn’t vary.

The researchers also identified a fourth distinct risk pattern previously unexamined in research pertaining to a group of boys who may be underserved by practitioners. Boys in this group, which composed about 15 percent of the sample population, had positive social skills but moderate problems with learning, anxiety and conduct.

“Although these boys may be socially skilled, their other problems can lead to increased aggression and substance use as they progress through middle school,” Tan said.

boy walking on train tracks

These youths’ social skills may account for their heightened verbal aggression, the researchers hypothesized, because “these boys are more attuned to how to utilize indirect forms of aggression as a means of harming others and, over time, become more accustomed to dealing with interpersonal matters through non-physical means.”

Alcohol and marijuana use increased among boys in this group, but at lower rates than their peers in the high-risk group. Tan and his co-authors suggested that these social boys may be more susceptible to negative peer influences that lead to experimentation with alcohol and drugs.

“Understanding these configurations of social-emotional, learning and conduct problems can help us understand how they elevate or decrease students’ risks for different outcomes,” Tan said. “There are opportunities here for schools to provide early prevention and interventions to address any problems before they become severe.”

ABOUT THIS NEUROSCIENCE RESEARCH ARTICLE

Funding: The data used in the study were drawn from the Multisite Violence Prevention Project, a middle-school violence prevention study funded by the Centers for Disease Control and Prevention.

Source: Sharita Forrest – University of Illinois
Publisher: Organized by NeuroscienceNews.com.
Image Source: NeuroscienceNews.com image is in the public domain.
Original Research: Abstract for “Patterns of Social-Emotional Needs and Trajectories of Aggression and Substance Use Among Middle School Boys” by Kevin Tan, Deborah Gorman-Smith, Michael Schoeny, Yoonsun Choi in Journal of Early Adolescence. Published November 29 2018.
doi:10.1177/0272431618812740

CITE THIS NEUROSCIENCENEWS.COM ARTICLE
University of Illinois”Boys with Social Difficulties More Susceptible to Early Substance Use.” NeuroscienceNews. NeuroscienceNews, 3 December 2018.
<http://neurosciencenews.com/social-boys-substance-use-120195/&gt;.

Abstract

Patterns of Social-Emotional Needs and Trajectories of Aggression and Substance Use Among Middle School Boyss

Co-occurring social-emotional problems are associated with increased risk of aggression and substance use. However, few studies examine their configurational patterns. This study identifies patterns of co-occurring social skills, anxiety, learning, and conduct problems among 2,632 urban boys at entry into sixth grade, and their related aggression and substance use trajectories through eighth grade. Latent class analysis revealed four patterns at school entry: “low-all,” “poor social skills,” “positive social skills,” and “high all.” Findings point to important variation in risk. Problem behaviors increased the least through middle school for the “low-all” pattern. The “positive social skills” pattern had an average increase, while the “poor social skills” pattern had higher levels of problem behaviors in sixth and seventh grade. The “high all” showed the fastest increase in problem behaviors and the highest levels in eighth grade. Discussion focuses on implications for a multi-tiered school-based system of supports for behavioral risk management.

A Toxin That Travels From Stomach to Brain May Trigger Parkinson’s

A Toxin That Travels From Stomach to Brain May Trigger Parkinson’s

Summary: A new study reports the combination of a toxic herbicide and lectins may trigger Parkinsonism after the toxins travel from the stomach to the brain.

Source: Penn State.

Combining low doses of a toxic herbicide with sugar-binding proteins called lectins may trigger Parkinsonism — symptoms typical of Parkinson’s disease like body tremors and slowing of body motions — after the toxin travels from the stomach to the brain.

In a study with rats, researchers at Penn State College of Medicine found that after ingesting paraquat, a once widely used herbicide that has been banned in the U.S. since 2007, along with lectins — sugar-binding proteins found widely in nature — the animals developed Parkinsonism.

According to Thyagarajan Subramanian, professor of neurology and neural and behavioral sciences and co-author on the study, the findings — recently published in the journal Parkinson’s Disease — offer clues to how and why Parkinson’s disease develops, and offer a model to test new medications in the future.

“This study gives solid evidence that lectins, while in the presence of certain toxins, may be one potential culprit for the cause of Parkinsonism,” Subramanian said. “Additionally, this animal model can be a tool in the future to continue developing new medications and treatments for Parkinson’s disease.”

The researchers were able to track the formation and spread of a misfolded protein called alpha-synuclein, which previous research has linked with Parkinson’s.

“We were able to demonstrate that if you have oral paraquat exposure, even at very low levels, and you also consume lectins — perhaps in the form of uncooked vegetables, dairy or eggs — then it could potentially trigger the formation of this protein alpha-synuclein in the gut,” Subramanian said. “Once it’s formed, it can travel up the vagus nerve and to the part of the brain that triggers the onset of Parkinson’s disease.”

R. Alberto Travagli, professor of neural and behavioral sciences and senior author of the study, said that while toxins like paraquat have been suspected of contributing to Parkinson’s for decades, the scientific evidence was small. While paraquat was linked with Parkinsonism in previous studies, those experiments typically used high doses of paraquat that humans were not likely to encounter in real life.

Additionally, lectins, which are used in medications to help deliver substances into the brain or stomach, also have been associated with certain rare forms of Parkinsonism. But the researchers weren’t sure if it was the lectins themselves that were causing Parkinsonism, or if they were helping different substances get into the body that then triggered the symptoms.

“Experimenting with the lectins together with the toxin makes sense, because lectins are used in pharmacology to chaperone other substances into the body,” Travagli said. “So it makes sense that the two can be combined and used to make the toxicity more potent, even though the amount of toxin is very low.”

Using a rat model, the researchers exposed the animals daily to small doses of paraquat and lectins for seven days. After stopping the treatment, the researchers waited two weeks. Then, the researchers did a variety of tests to measure problems with motor function and other symptoms typical of Parkinsonism.

stomach

The researchers observed a decrease in motor function that was consistent with Parkinsonism. But to confirm that the symptoms were related to Parkinsonism and not another cause, Travagli said he and the other researchers did several additional tests.

“After observing that these animals did indeed show symptoms of Parkinsonism, we wanted to double check and make sure we weren’t looking at animals that had these symptoms for another reason,” Travagli said. “We administered levodopa, which is a common medication for Parkinson’s disease. We saw a return to almost normal types of motor responses, which was a clear indication that we were looking at some sort of Parkinsonism.”

Additionally, the researchers said when the vagus nerve was disconnected from the stomach prior to exposure to paraquat and lectins, the animals were protected from Parkinsonism, confirming the route of the alpha-synuclein from the gut to the brain.

In the future, Travagli and Subramanian said they will explore whether interventions in the form of diet modifications or medications that interfere with the transport of alpha synuclein from the stomach via the vagus nerve could be used to help prevent or slow the development of Parkinsonism in this rat model. This includes a natural substance called squalamine which has been shown to remove alpha synuclein from the gut and is now in clinical trials for the certain symptoms associated with Parkinson’s disease.

ABOUT THIS NEUROSCIENCE RESEARCH ARTICLE

Laura Anselmi, research associate; Cecilia Bove, doctoral student in neuroscience; F. Holly Coleman, lab manager; K. Le, research technologist; Megha Subramanian, research technologist; and Kala Venkiteswaran, assistant professor of neurology, also worked on this research.

Funding: This research was supported by the National Institutes of Health, the Michael J. Fox Foundation for Parkinson’s Disease and the Tobacco Settlement Fund.

Source: Katie Bohn – Penn State
Publisher: Organized by NeuroscienceNews.com.
Image Source: NeuroscienceNews.com image is in the public domain.
Original Research: Open access research for “Ingestion of subthreshold doses of environmental toxins induces ascending Parkinsonism in the rat” by L. Anselmi, C. Bove, F. H. Coleman, K. Le, M. P. Subramanian, K. Venkiteswaran, T. Subramanian & R. A. Travagli in Parkinson’s Disease. Published September 27 2018.
doi:10.1038/s41531-018-0066-0

CITE THIS NEUROSCIENCENEWS.COM ARTICLE
Penn State”A Toxin That Travels From Stomach to Brain May Trigger Parkinson’s.” NeuroscienceNews. NeuroscienceNews, 4 December 2018.
<http://neurosciencenews.com/stomach-toxin-parkinsons-120203/&gt;.

Abstract

Ingestion of subthreshold doses of environmental toxins induces ascending Parkinsonism in the rat

Increasing evidence suggests that environmental neurotoxicants or misfolded α-synuclein generated by such neurotoxicants are transported from the gastrointestinal tract to the central nervous system via the vagus nerve, triggering degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and causing Parkinson’s disease (PD). We tested the hypothesis that gastric co-administration of subthreshold doses of lectins and paraquat can recreate the pathology and behavioral manifestations of PD in rats. A solution containing paraquat + lectin was administered daily for 7 days via gastric gavage, followed by testing for Parkinsonian behavior and gastric dysmotility. At the end of the experiment, brainstem and midbrain tissues were analyzed for the presence of misfolded α-synuclein and neuronal loss in the SNpc and in the dorsal motor nucleus of the vagus (DMV). Misfolded α-synuclein was found in DMV and SNpc neurons. A significant decrease in tyrosine hydroxylase positive dopaminergic neurons was noted in the SNpc, conversely there was no apparent loss of cholinergic neurons of the DMV. Nigrovagally-evoked gastric motility was impaired in treated rats prior to the onset of parkinsonism, the motor deficits of which were improved by L-dopa treatment. Vagotomy prevented the development of parkinsonian symptoms and constrained the appearance of misfolded α-synuclein to myenteric neurons. These data demonstrate that co-administration of subthreshold doses of paraquat and lectin induces progressive, L-dopa-responsive parkinsonism that is preceded by gastric dysmotility. This novel preclinical model of environmentally triggered PD provides functional support for Braak’s staging hypothesis of idiopathic PD.

When a cancer or internist doctor advice for 24/7 home care

Doctors are recommending 24/7 home care with a caregiver to help a patient with terminal illness or a senior in hospice care be comforted and have a companion while being home-bound or bed-bound. A caregiver can bring personalize care that family members cannot provide. There are more tasks that a 12 hour shift or live-in caregiver can provide providing respite care and needed help for the family who also helps in the care.

Some patients who are dying do not sleep at night. Many seniors never experienced being massaged and Motherhealth caregivers provide loving touch massage.

They are exercised while sitting or lying on their bed. Exercise, massage and hugs are what define Motherhealth caregivers who assist in daily living, performs light housekeeping and monitors health.

Trained and also monitored, caregivers can cook gourmet meals suited to the health needs of the client.

Text 408-854-1883 to learn how to match caregivers with your parents who are bed-bound or home-bound. Let quality of life be within reach.

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Free consultation and assessment with caregiving needs here…

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Why seniors are hesitant to be cared for by caregivers

Those who have lived independently are resistant to living with a companion caregiver. Sometimes, those who are still denying their health issues do not want to be cared for and only wish to live at their homes and be cared for by their families for cost and trust reasons.

Having a companion can mean more freedom for your other family members. Motherhealth caregivers offer massage, home cooked meals, light housekeeping and assistance in daily living. We treat seniors like family. Text 408-854-1883 to try our service in the comfort of your home, apartment , rehab or senior living facilities.

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How to know if you found the right match with a caregiver

Express your wishes to the case manager of an agency or your family for what traits you looking for in a caregiver.

Try the caregiver first and communicate how you want to be cared for. After a day, you can decide to hire the agency or the caregiver.

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How to prepare massage oils for seniors

Ask seniors if they are sensitive to smell. Some seniors with Epilepsy and ALS do not like smells so use coconut oil as base and only add few drops of rosemary and eucalyptus oil.

Some seniors prefer back massage than foot massage. Most health issues can be helped with foot and leg massage. Do light touch when a person is suffering from vascular issues.

I prefer fresh ginger and oil base of apricot oils for those with pain and inflammation. Suggest to take supplement of turmeric and ginger capsul, up intake of greens and whole foods rich in Vitamin C.

Enter you health issue and email for specific massage oil for your condition here.

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Holistic health care team for seniors

Join us if you want to create a nursing facility, assisted living for seniors and other facilities that will provide holistic senior care.

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Pool of nurses and other health care team

Email motherhealth@gmail.com your resume if you want to work in the clinical and hospitals in the bay area. (LVN, RN, CNA, case manager, PT , OT, nurses (clinical, surgery, OB, others).

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Students as companion-caregiver for bay area seniors for free room rent

We connect students who want to have a room to stay and also provide few hours of companion-caregiving work for bay area seniors. Text or call 408-854-1883. Free training and health monitoring of both seniors and caregivers.

Holistic senior care may include companionship, driving, cooking, light housekeeping, assistance in daily living and other tasks.

Motherhealth LLC cares for seniors and integrates holistic caregiving with exercise, massage and hugs.

We treat seniors like family and wanted seniors to treat caregivers also like family. Together , we can build respect with each other and promote positive environment for all to promote wellness.

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