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When to eat should be in sync with our regular rhythms

An occasional late-night raid on turkey leftovers might be harmless but new research with mice suggests that making a habit of it could alter brain physiology.

Eating at times normally reserved for causes a deficiency in the type of learning and controlled by the hippocampal area of the brain, according to findings in the journal eLife.

Researchers from the Semel Institute in the David Geffen School of Medicine at University of California, Los Angeles (UCLA) became interested in the cognitive effects of eating at inappropriate hours because it is already known to have an impact on metabolic health, for example leading to a pre-diabetic state.

Regular meals at regular time

“We have provided the first evidence that taking regular meals at the wrong time of day has far-reaching effects for learning and memory,” says first author Dawn Loh from the UCLA Laboratory of Circadian and Sleep Medicine.

“Since many people find themselves working or playing during times when they’d normally be asleep, it is important to know that this could dull some of the functions of the brain.”

The researchers stress that their findings have not been confirmed in humans, but highlight the fact that shift workers have been shown to perform less well on cognitive tests.

Affecting learned behaviours

The current study shows that some learned behaviours are more affected than others. The team tested the ability of mice to recognise a novel object. Mice regularly fed during their sleep-time were significantly less able to recall the object. Long-term memory was also dramatically reduced, demonstrated during a fear conditioning experiment.

Both and the ability to recognise a novel object are governed by the hippocampus. The hippocampus plays an important role in our ability to associate senses and emotional experiences with memory and our ability to organise and store new memories.

During an experience, nerve impulses are activated along specific pathways and, if we repeat the experience, the same pathways increase in strength. However, this effect was reduced when food was made available to mice during a six-hour window in the middle of their normal sleep time instead of a six-hour daytime window when the mice were active.

Genes involved in both the circadian clock

Some genes involved in both the circadian clock and in learning and memory are regulated by a protein called CREB (cAMP response element-binding protein). When CREB is less active, it decreases memory, and may play a role in the onset of Alzheimer’s disease. In the mice fed at the wrong time, the total activity of CREB throughout the hippocampus was significantly reduced, with the strongest effects in the day.

However, the master pacemaker of the circadian system, the suprachiasmatic nucleus located in the hypothalamus, is unaffected. This leads to desynchrony between the clocks in the different brain regions (misalignment), which the authors suggest underlies the memory impairment.

“Modern schedules can lead us to eat around the clock so it is important to understand how the timing of food can impact cogitation” says Professor Christopher Colwell from the Department of Psychiatry and Biobehavioral Sciences at UCLA.

“For the first time, we have shown that simply adjusting the time when food is made available alters the molecular clock in the hippocampus and can alter the cognitive performance of mice.”

Disrupt sleep patterns

Eating at the wrong time also disrupted sleep patterns. The inappropriate feeding schedule resulted in the loss of the normal day/night difference in the amount of sleep although the total time spent asleep over 24 hours was not changed. Sleep became fragmented, with the catching up on sleep by grabbing more short naps throughout the day and night.

Relaxed digestion, constipation and losing weight

You Control Your Metabolism

 How energetic you feel and what body weight or mass you maintain are determined by how you regulate your metabolism with the food and activity choices you make. Five factors affect this dramatically:

  • Whole foods: Consumption of high-energy, healthy foods vs. low-energy, poor food choices
  • Calories: Total food consumed in a meal vs. energy required over the next few hours
  • Exercise: Average total physical activity expended during a day
  • Sleep, toxins and whole foods: Proper hormone function
  • Whole foods, clean water, clean air: The pH balance of your bodily fluids

Balance in minerals, fats, oils to control weight

When these factors are properly balanced you can control your weight as you wish. While the first three of the above are pretty obvious, many are not aware that the fourth factor, proper hormone function, is very important, and dramatically affected by the types of food you ingest, particularly by the ratio of various minerals, sugars, fats and oils in the diet.

The fifth factor, pH balance, is affected by the quality and ratio of various minerals, carbohydrates, proteins, oils and fats you eat. The charts provided below will make it easy for you to pick the foods best for you.

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There are many different types of protein, sugar, carbohydrate, fat and oil discussed below. You may not recognize various terms at first, but each type is explained.  If you are just learning about foods, you should read these sections once to become familiar with the terms and general message, and then read it again for better comprehension and retention. The appendix also contains several books which discuss all of this in greater detail, and very concisely as compared to many texts.

If You Need to Lose or Gain Weight

 Proper dietary choices combined with moderate exercise are the answer to losing or gaining weight. The food choices you make (particularly as applies to carbohydrate and oil) determine whether the body ingests foods that speed up or slow down human metabolism. For example excess consumption of simple sugars makes you fat. Increased consumption of healthy oils, like flax oil, increases oxygen uptake & transport, raising metabolism and burning calories. Exercise levels and other daily activity also determine whether you will stimulate or depress your metabolism.  All of this is discussed in detail in the sections below.

The Importance of Proper, Relaxed Digestion

 Digestion requires more energy than any other bodily function. Processing food is the single most important bodily function to an animal‘s survival, and as such, is a biological priority.

Thinking uses enormous amounts of energy as well. This is why you can fall asleep after a heavy meal—as all of your energy required to stay alert is temporarily diverted to digestion.

Good digestion requires healthy food, a relaxed atmosphere, and thorough chewing of food. Incomplete digestion can lead to serious health problems.

All digested food that we use passes from our digestive system into the bloodstream. In a utopian world our blood would only contain substances that are good for us, however there are many ways for pathogens to enter the bloodstream—through organisms and contaminants in the foods we eat and drink; contaminated air we breathe; insect bites, cuts and other perforations of the skin; etc.

The digestive system is the foundation of our immune system strength. Proper gastrointestinal function is critical to adequate nutrient delivery and can impact all aspects of body function and our health.

Any digestive disorder has the potential to cause nutritional deficiencies which can cause disease.  As well, the digestive system is designed to keep invading organisms out of our bodies.

A simple analogy is helpful in understanding the basic form of our digestive system as it relates to the rest of the body. Consider the geometry of a donut shaped object. The human body‘s fundamental form is similar to that of a donut.

The inside surfaces of our mouth, throat, stomach and intestines – everything that we call our digestive tract (i.e. the donut hole) – is continuously connected to the outside surfaces of our body, that we call skin (i.e. the outside of the donut). If we stretch our imaginary donut into a longer tube, the digestive tract is still on the inside, and our skin is on the outside. The inside and outside surfaces make up one continuous unbroken surface.

This simple geometric analogy teaches us that, anatomical differences aside, a common trait shared by our skin and our digestive tract is that they both face outward from the body. Nature designed us this way to provide a continuous protective barrier from the outside world.

The human body‘s immune system is designed to attack foreign complex molecules (combinations of simple molecules) not made by our own bodies. This is one of the reasons Nature evolved our bodies to require full digestion of our foods for proper health. To ensure our immune system to functions properly, we are designed to break down complex food groups into their smallest parts, and to later reassemble them into the more complex parts specific to our individual needs and familiar to the immune system. Therefore complete digestion is critical to proper function of the immune system.

If a person is not fully digesting his/her foods a number of problems arise.  For example:

  • Partially digested food molecules are usually too large and in the wrong chemical form to pass into the
  • Partially digested food is not available to many of the body‘s enzymes requiring foods in their simplest
  • Undigested food can also feed other unfriendly organisms in your digestive track. This can lead to and overgrowth of yeast and bacteria leading to gas, bloating, and chronic infection.
  • Should you develop ―leaky gut syndrome‖, where a weakened digestive system allows undigested food or waste to pass from the small or large intestine into the blood stream, this can cause food allergies and other adverse reactions as the immune system attacks the complex molecular structure of the ―unknown invader‖.

Many of us take digestion for granted. This is a big mistake, because most health problems ultimately result from a nutritional deficiency, or a digestive disorder that prevents us from absorbing various nutrients properly. The first line of defence for a healthy immune system is a healthy digestive system.  Improper digestion almost always leads to disease.

The Electrically Charged Building Blocks of Foods

 Food, like most other things on the planet are electrically balanced, or ―neutral‖ to touch. You will not get an electrical shock touching them. However this can be deceiving, as most compounds on the planet are made up of vast quantities of electrically unbalanced (or ―charged‖) acidic acids and alkaline bases.

As most people know, opposite electrical forces ―attract‖ and like forces ―repel‖. It‘s the electrically unbalanced, or polar, nature of the microscopic components of our food which make them healthy for us. Nature is able to move things around in our bodies primarily due to electrical attraction or repulsion.

Therefore one of the things your body must first do is to break down ―neutral‖ foods into their dynamic and reactive acidic and alkaline building blocks.

 

How Various Parts of Your Digestive System Work

 For a brief overview of the many parts of the Digestive system and their many functions, if you are on line, please refer to the Virtual Anatomy Textbook-Digestive System on the web.

There are four basic parts of the digestive system for breaking down your food (the mouth, stomach, pancreas, and small intestine) and two for the elimination of wastes (the colon and kidneys). The four digestive sections are responsible for the acidic and alkaline breakdown of your food.

The first alkaline digestion of carbohydrates starts in the mouth with enzymes found in your saliva. This is why thorough chewing of your food is so important, as without thorough chewing this initial alkaline breakdown is less complete.

This is also why rapidly digesting refined foods can accelerate rotting of teeth. If there were no enzymes in your saliva, this carbohydrate could harmlessly sit on your teeth doing nothing as it does on a cupboard shelf. However refined carbohydrates react with enzymes to produce simple sugars too rapidly, wreaking havoc on your teeth and mouth.

Next the chewed food is soaked in an acid bath contained in your stomach. (The very powerful acids in your stomach are contained within the alkaline lining of the stomach‘s walls. The stomach needs adequate bio-available sodium to maintain this protective alkaline lining.) Some simple foods and nutrients are passed through the stomach lining into the bloodstream, but most do not enter the blood until they pass through the small intestine.

Nature has evolved our bodies to makes sure everything is broken down into its simplest forms. Once the food has had its first alkaline and acidic digestion, our body‘s repeat this process a second time. Our partially digested food once again goes through an alkaline breakdown in the duodenum, the uppermost section of the small intestine, with secretions from the pancreas. If we are not chewing our food properly to achieve adequate alkaline digestion in the mouth, we can put unnecessary strain on the pancreas.

Next, this slurry of nutrients, or chyme, heads to the acidic middle section of the small intestine, for the final acidic breakdown of our foods. Bile, first manufactured in the gall bladder, and then stored and secreted from the liver, helps to digest fats and oils. With digestion and nutrient breakdown complete, the majority of dissolved nutrients pass through the small intestine‘s walls into the bloodstream, about 3-4 hours after we have eaten it.

The acidic liquids of the small intestine now need to be neutralized and dried out. This occurs in the large intestine or colon and take about 8 hours (if you are regular—with 2 or more normal bowel movements per day). The large intestine represents the terminal phase in digestion. Here, large amounts of water and salts are reabsorbed back into the blood and recycled, leaving only the familiar fecal matter. Unlike the fast-moving chyme in the small intestine, this fecal matter moves slowly and contains few nutrients and much less water. A properly functioning colon contains 3 meals most of the time.

However, if you are lacking regularity, one bowel movement or less, you probably have 6 meals in the colon at once. Chronically constipated people often have as many as 8-9 meals in the colon at once. As described below, this is not a healthy situation, but it usually can be improved quickly with a change of diet and/or exercise.

Constipation is a Slow Killer

 The colon is designed for continuous expelling of waste and toxic substance. If this process is slowed on a chronic basis, a person risks increased chance of reabsorbtion of waste and toxins into the body, causing auto-intoxication which can lead to any number of serious degenerative diseases.

Adequate exercise, water, essential fatty acids, and vegetables (for alkaline mineral, fiber and roughage) are important for maintaining regularity. Eat in a relaxed environment and at regular hours. Chew your foods well.

Exercise keeps the abdomen physically moving, thereby stimulating elimination. Too much exercise can disturb digestion as well, particularly if too soon after a meal.

Because digesting protein requires adequate water, high protein diets can cause dehydration which can lead to constipation. Athletes ingesting additional pure protein powders require a lot of extra water to prevent dehydration, constipation, and muscle cramping associated with dehydration.

Flax oil and the other essential fatty acids help keep the colon healthy, as well as improving flow of material.  Healthy stools should be firm, but slightly softer rather than hard.

Two to three regular bowels movements per day is optimum. Once a day, is not enough and indicates that one is slightly constipated. Anything less is usually a problem that will lead to health problems in the longer term.

 

Total Food Digested in One’s Life and Lifespan

 Studies on mice have led many researchers to predict the body can only digest a limited amount of food over a life time. While there are many factors associated with aging, even if these researchers are only partly right, it would make sense to eat the foods that are most easily digested while providing the richest source of nutrients. And even if they are wrong, this still makes sense, as your body functions best on nutrient rich food.

 

Using Food and Your Body Efficiently

 Building cells takes energy and uses up one‘s available lifespan. Once we have reached adult age, cellular replication slowly becomes less effective and efficient with each new copy.

Therefore once cells have been developed, you want to preserve their health as long as possible. When they age, or are damaged (degenerate), one wants to regenerate news ones as efficiently as possible. Such regeneration requires nutrients, energy, and chemical processing. The less regeneration we need to do, the better, as it‘s less work for our body.

Proper work and exercise choices are essential to maintaining healthy muscles and body parts with a minimum of regeneration and energy. For example, by eating the wrong foods, or by running out of the right fuel to provide fuel for a particular activity, you can unwittingly cause your body to cannibalize itself.

This is because the brain only runs on sugar available in the blood (blood sugar levels are the product of carbohydrate digestion, see below). If you run too low on blood sugar, the body must break down proteins (usually from muscle) into the sugars required for brain function. The body is unable to make sugars for the brain from fat. Fat can only be burned as a slower burning fuel for muscle.

Therefore intensive mental activity for long periods of time without adequate proper carbohydrate consumption will cause muscle wasting to occur. Eating protein to fuel the brain is very inefficient, as protein digestion is energy intensive and taxing on the kidneys, as excess nitrogen (in the form of toxic ammonia) produced by metabolizing protein must be removed as urine. To prevent muscle wasting, adequate long chain carbohydrates should be consumed to provide a slower burning, steady supply of sugar to the active brain, as described below.

Strenuous physical and mental activity also produce acid by-products in our body. Acids are produced when there is a lack of oxygen and other key nutrients to burn fuels properly in our body. As you will learn below, various foods and nutrients prevent our cells from overproducing acid and protect us from the destructive actions of acid build-up in our tissues.

However, those who work too hard without proper foods and rest can overwhelm their cells ability to eliminate acid.  They develop a silent and serious condition known as acidosis.

Assuming a sick person‘s problems are not the result of environmental contamination or other toxins, acidosis is now considered by many health practitioners to be at the root of much degenerative disease, including many cancers.

While many parts of a cell are designed to handle longer exposures to acidic conditions, other sensitive cell structures, such as our DNA are not.

As is discussed further below, three primary factors allow an excessive buildup of acid in the body:

  • The consumption of the wrong balance of
  • A lack of moderate exercise, which keeps our tissues saturated in oxygen and our lymph system
  • Continuous excessive anaerobic exercise, which can generate too much acid for the body to
  • Continuous high stress of any

Acidosis refers to a general build-up of acid in all of our body‘s cells. Do not confuse this acid build-up, with acid reflux that causes heartburn, although acidosis can certainly contribute to acid reflux.   Acidosis refers to the acid level in all of our cells, not just those in the digestive tract. And, while strong acids play an essential role in digestion and other processes, in a healthy body those powerful digestive acids are contained by special mucous linings in our digestive tract.

Sam Bock

Click to access genetics.pdf

Nutrition affects our genes

Our genetic systems appear to be primarily controlled and/or altered by the foods and other chemicals we ingest.

Most people have been led to believe that one‘s genetic system is at the root of most serious health problems one may encounter. In most cases this simply is not true, as the latest research shows.  In the years ahead, how the West views medicine and illness will dramatically change.

In November 2005 conventional medical researchers finally confirmed what orthomolecular medical and environmental researchers have understood for years – that specific foods and chemicals turn genes on and off, and affect ongoing genetic expression.2 This understanding will eventually cause a revolution in the way future drugs are developed.  Many of our modern disease states are primarily a result of pollution, malnutrition, and/or improper exercise habits.

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Such factors are dramatically affecting ongoing genetic development and health in people.

To some it may sound implausible – that simply eating a specific food or supplement, could permanently change your behaviour for the better, or reverse diseases such as schizophrenia,

Huntington’s or cancer.3 However, in the latest research, normal rats have been made to behave differently just by injecting them with a specific amino acid (a building block of protein). The change to their behaviour was permanent.4 The amino acid altered the way the rat’s genes were expressed.5

This is now raising the idea amongst conventional medical researchers that drugs, dietary supplements, and/or other nutrients might permanently halt the genetic effects that predispose people to mental or physical illness, just as orthomolecular medical researchers have shown for 25 – 30 years.

Dr. Linus Pauling first proposed the term Orthomolecular Medicine in 1968 in the journal Science. (One of the greatest thinkers of the 20th century, Pauling was one of the fathers of modern chemistry, having won the Nobel prize for describing the nature of the electron. He also made many important medical research discoveries. In addition, along with Watson and Crick, his research was critical to the discovery of DNA, the backbone of all life on Earth.)

In practice, the orthomolecular doctor relies heavily on laboratory testing.  In addition to standard clinical chemistries, orthomolecular doctors now employ a wide range of sophisticated laboratory analysis, including those for testing levels of amino acids, organic acids, vitamins and minerals, functional vitamin status, hormones, immunology, microbiology, and gastrointestinal function. Many of the newer tests have yet to be adopted by most in conventional medicine.

Orthomolecular medicine prescribes the use of natural substances found in a healthy diet such as vitamins, dietary minerals, enzymes, antioxidants, amino acids, essential fatty acids, dietary fiber, phytonutrients, etc. in the prevention and treatment of diseases. It focuses on the role of proper nutrition & exercise in relation to health. Nutrition and/or nutritional intervention comes first in medical diagnoses and treatment – drug treatment is used only for specific indications.

Orthomolecular medicine is defined as the provision of the optimum molecular constitution, especially the optimum concentration, or balance, of substances that are normally present in the body, for the purposes of treating disease and preserving health. The field of orthomolecular psychiatry deals with the use of orthomolecular medicine to treat psychiatric problems.

This paper is designed to show you how to choose foods to enjoy a full and vibrant life.

Our genetic systems can not adapt to change quickly.

The very gradual evolution of our genetic systems was the product of millions of years of exposure and adaptation to natural chemicals and unpolluted foods.  However, in just 60-70 years the modern world and the physical environment in which we live have rapidly changed. As a result, a combination of factors are now dramatically affecting our health.  These are:

  • Excess stress due to high paced lifestyles,
  • Modern technologies yet to been proven as safe – including intensive agricultural farming methods, processed foods, many modern electrical devices, and certain medical practices,
  • high levels of industrial and agricultural pollution,
  • and a lack of proper exercise.

America spends more money per capita on health care than any other country. Yet it is one of the unhealthiest societies, leading the world in obesity and with 73.5% of deaths caused by degenerative disease in 2001.6   Canada is not far behind.

Junk foods, such as sugary sodas and chips make up nearly one-third of calories in the U.S. diet.7 Moreover, Americans consume approximately 50% of the world‘s pharmaceutical drugs.8 North American seniors are taking an average of eight to twelve prescription drugs daily for multiple health problems.9 Britons spend about ¼ as much and live just as long10, although they also are suffering serious health problems as a result of their ―modern‖ western living.

While Americans are ―living as long as most western counterparts, many spend their last years in hospitals and homes.

Canada has the highest cancer death rate in the G8, and the second highest rate in the world.11 Few Canadians realize Ontario is ―officially‖ one of the most polluted places in North America.12 Even fewer realize that ―unofficially‖ hundreds of thousands of pre-regulation oil well sites in Alberta, B.C., Saskatchewan, and the northern territories contain shallowly buried toxic dumps of diesel fuel and radioactive materials which are seeping into the water table.

Many Canadian cities and towns are highly polluted due to previous and/or ongoing unregulated industrial, forestry, and/or agricultural activity.

An understanding of the connection between nutrition and cellular replication became possible ever since two critical discoveries:

  1. a) DNA‘s role in cell division and replication, and
  2. b) the precise nature of the enzyme action that make it possible.

Because of these, we now known that anything interfering with normal enzyme balance or activity will first cause a chain reaction of problems within the organism, and then again further up the food chain, when that organism is consumed by another.

This new understanding places primary responsibility for health on the individual (which can choose its nutrition), rather than on a genetic act of God (for which we are helpless).

These ever-growing realizations by the public at large are creating a revolution in consumer attitudes towards health care options before them.

Nutrition affects the actual replication of genes every time a cell divides.

The reasoning is simple: if any of the many levels of enzyme activity required for the copying of DNA is compromised by nutritional factors, how can the body make accurate copies of DNA and other derivative genetic structures in the body?

Most MDs only received about 6 hours of nutrition classes in 4400 hours of training.

As of 1989, of the approximately 130 medical colleges in North America, less than 25% had courses on nutrition. On the other hand, graduates of the 4 CNME certified naturopathic medical colleges in North America have 200 hours of academic classes, and 1000 hours of clinical nutrition.

But change is slowly coming. North American Medical schools are now rapidly adapting to expand training in Nutrition and alternatives practices as well. Many conventional medical practitioners are establishing integrated medical clinics, which offer a wide and comprehensive range of medical services. That said, it will be many years before the majority of doctors are up to speed on nutrition and its affects on genetics.

Sam Bock

Click to access genetics.pdf

 

Thyroid Health by Dr Mercola and health tips for a new mom with Hashimoto

Dear new mom,

I am glad that you are looking for a health coach since you are breastfeeding and as new mom needs all the essential nutrition and support you need more than ever. Email me at motherhealth@gmail.com to give you daily coaching on what to do with food choices, choices of exercise, losing weight, breastfeeding and more. Choose whole foods, cooked the greens, add cilantro and lemon in your dish, vinegar from pickled veggies, probiotic and relaxation.

A gym coach is important for your goal of losing weight but do eat all the healthy foods as you are still breastfeeding by using light weights for cross-fit.  I use NC.FIT 30min cross fit on Stevens Creek, mention my name to enroll for 30-min per day, $60 per mon cross fit coaching group class.

Blessings,

Connie Dello Buono ; motherhealth@gmail.com

Thyroid disease is one of the most common health problems we face today. From a practical standpoint, there are many ways to approach this issue. In this interview, Dr. Jonathan Wright, a pioneer in natural medicine, shares his protocols for addressing thyroid dysfunction.

Hypothyroidism, or underactive thyroid, is a very common problem, and there are many reasons for this, including drinking chlorinated and fluoridated water, and eating brominated flour.

Chlorine, fluoride, and bromine are all in the same family as iodine, and can displace iodine in your thyroid gland.

Secondly, many people simply aren’t getting enough iodine in their diet to begin with. The amount you get from iodized salt is just barely enough to prevent you from getting a goiter.

A third principal cause of hypothyroidism is related to elevated reverse T3 levels. Interestingly, 95 percent of the time, those with elevated reverse T3 levels will see their levels revert back to normal after undergoing chelation with EDTA and DMPS, which draw out cadmium, lead, mercury, and other toxic metals. In essence, heavy metal toxicity can cause a functional form of hypothyroidism.

“It’s very well-known that lead and cadmium interfere with testosterone production,” Dr. Wright says. “What’s not so well-known is that reverse T3 is stimulated by toxic metals, so up it goes.

In effect, we can have levels that are so high, they way outnumber the regular T3. You’re functionally hypothyroid even if your TSHs and free T3s happen to be normal.”

How Much Iodine Do You Need for Thyroid Health?

In Japan, the daily dose of iodine obtained from the diet averages around 2,000 to 3,000 micrograms (mcg) or 2-3 milligrams (mg), and there’s reason to believe this may be a far more adequate amount than the US recommended daily allowance (RDA) of 150 mcg.

Some argue for even higher amounts than that, such as Dr. Brownstein, who recommends 12.5 milligrams (mg) on a regular basis. Another proponent of higher iodine amounts is Guy Abraham, an ob-gyn and endocrinologist at the University of Southern California.

“Oddly enough, he didn’t publicize [his publications] much until he retired from the University of Southern California. But after that, he came out with a wonderful website, optimox.com, where you can read a lot of stuff for free,”Dr. Wright says.

“There’s a fairly careful study showing that the thyroid gland does not start to downregulate until we get to 14 or 14.5 milligrams of total iodine and iodide. This is probably why Dr. Abraham first, and then others, have designed both liquids and tablets that come out with 12 or 12.5 mg.

Oddly enough, in 1829, Dr. Lugol put together a combination of iodine and iodide. Two drops of that stuff equals exactly to 12.5 milligrams. How did Dr. Lugol know? We don’t know. But it works so well for people ever since 1829 that it’s still available (with a prescription) as Lugol’s iodine…

Usually, in my practice, I’ll say, ‘One drop of Lugol’s, which is six milligrams; six and a quarter.’ Or for the guys, who don’t have as much massive breast tissue, let’s stay with three milligrams. [To] prevent cancer, I want more than three milligrams for the ladies.”

Iodine Helps Protect Breast Health Too…

From Dr. Wright’s experience, there are no adverse effects from taking upwards of 12.5 mg of iodine per day, and in some cases higher amounts may benefit more than your thyroid. There’s compelling research suggesting that iodine is equally important for breast health, and that iodine – not iodide – combines with a lipid to form molecules that actually kill breast cancer cells.

“Breasts are big sponges for iodine,” Dr. Wright notes. “Not iodide so much; that’s the thyroid gland. But if you have enough iodine, why, those molecules are just sitting there ready waiting to kill new breast cancer cells!”

According to Dr. Wright, iodine is also crucial for other breast-related problems, such as fibrocystic breast disease, for which iodine works nearly every time. Interestingly, for severe cases, it’s recommended to swab the entire cervix with iodine.

“For bad cases, you got to work with your doctor. Get the iodine swab done,”Dr. Wright says. “The worse the fibrocystic breast disease is, the more treatment it takes. But that one, I can almost give a money-back guarantee… because I never would have to give you your money back.”

That said, it would seem prudent for most to avoid taking such high doses unless they were using it therapeutically, for a short period of time. I personally feel that supplementation at a dose 10 times lower, or a few mg, might be best for most.

Good Sources of Iodine

Besides Lugol’s, seaweed or kelp is a great source of iodine. One that is oftentimes recommended by herbalists for thyroid health is a seaweed called bladderwrack (Latin name: Fucus vesiculosus). You can find it in either powdered form or in capsules. If you want, you can use it to spice up your meals, as it has a mild salty flavor. The downside is that to reach three milligram dose, you’ll need to take at least a couple of teaspoons per day.

Another concern is the potential radiation issue from the Fukushima reactor, which has contaminated much of the Japanese seaweed. So make sure you look at the source of your seaweed. Try to get it from the Norwegian Coast or as far away from Japan as you can get. While manufacturers have not started labeling their products as “radiation-free,” you could simply check the bottle with a Geiger counter before taking it.

Dr. Wright’s Thyroid Program

Dr. Wright always begins with a physical exam, where he looks for signs of thyroid dysfunction. This includes symptoms such as dry skin, thinning of the outer margins of your eyebrows, subtle accumulation of fluid in your ankles, constipation, lack of sweating, weight gain, and high cholesterol. An older yet helpful test is to take your temperature every morning and observing if your temperature registers close to 98.6.

This test stems from the work of Dr. Broda Barnes back in the ’30s and ’40s. Dr. Barnes found that if the temperature was low, it was a reliable indication of an underactive thyroid (hypothyroid). “These days, with all the other things going on, I find that sign useful in some people but not in others,” Dr. Wright says. “But I do want it for everybody.”

As for laboratory tests, the complete thyroid panel includes thyroid-stimulating hormone (TSH), total T4, free T4, total T3, free T3, and the reverse T3. He cautions against trusting the TSH test as a primary diagnostic tool, despite that being the conventional norm. He bases his recommendation on research by Dr. St. John O’Reilly, an expert on thyroid health at the University of Scotland, who has shown that the TSH test virtually never correlates with the clinical condition of the patient.

According to Dr. Wright, the TSH level doesn’t really become a valuable indicator of hypothyroidism unless it’s high, say around 5 or 10. Thyroid therapy has been around since the 1890s, and until the TSH test became the norm, the average dose of thyroid given was almost exactly twice what the average dose became when everybody started paying attention to the lab test rather than the clinical signs. Dr. St. John O’Reilly recommends basing the diagnosis on the physical exam and the Free T3 level instead, which is the protocol Dr. Wright follows in his clinic.

“The Free T3 is, of course, the free hormone, not the one bound up on the thyroid globulin, where it’s temporarily inactive,” Dr. Wright explains. “The Free T3 is the one that helps us to burn energy; it’s the active hormone. The Free T4 is waiting to become active, but it’s not active yet. It signals back to the TSH. But the Free T3 doesn’t signal back to the TSH as much as the Free T4 does.”

Meanwhile, the T4 is the type of thyroid replacement that is typically and traditionally given by almost every conventional physician. In my experience, it’s one of the primary ways you can differentiate between a natural medicine physician and a traditional conventional physician: the type of thyroid replacement they prescribe.

Complicating Matters: Autoimmune Thyroid

Unfortunately, most people who end up on thyroid hormone replacement are placed on synthetic thyroid hormone, again, typically T4, commonly prescribed under the brand names Synthroid or Levothroid. Traditional doctors almost always prescribe this, and anyone who doesn’t prescribe it is oftentimes severely criticized, and may even be called before their state medical board.

That actually happened to me, and I wasn’t even prescribing it. I have stopped seeing patients, but have written about it in this newsletter. I was called before the medical board to defend my position on prescribing bioidentical whole thyroid hormone rather than Synthroid or Levothroid—even though my article was supported by a study reference from the New England Journal of Medicine, a very prestigious journal. Dr. Wright also prefers bioidentical thyroid replacement, and typically starts patients out on whole thyroid derived from animals (typically cow, sheep, or pig).

“In the whole thyroid are all the things that nature and creation put into whole thyroid. That’s what we should be using unless you happen to have an autoimmune problem. Many people with… Hashimoto’s disease… make antibodies to thyroid. If you’re making antibodies to thyroid, I’m not sure that we should be putting in whole thyroid right away… because there is a small chance – it’s not a large chance – that we’re going to stimulate more antibody formation,” he says.

In those with Hashimoto’s disease, where your body is making antibodies against your thyroid hormones, Dr. Wright will typically start you out on T4 and T3, which are only two of the 12 iodinated substances your thyroid gland makes, and which are all found in whole thyroid.

The Role of Heavy Metal Toxicity

As mentioned at the beginning, one of the principal causes of hypothyroidism is related to elevated reverse T3 levels, which can become elevated in response to heavy metal toxicity. In such cases, Dr. Wright recommends detoxifying before beginning thyroid treatment. The detoxification protocol will vary depending on your level of lead, cadmium, mercury, and other heavy metals.

“Some people get these efficiently out of their bodies within 10 to 15 chelation treatments. There are other people, particularly those who lived in major metropolitan areas all their lives, where it takes 30 or 40 chelation treatments to pull out all the toxic metals,” he notes. “When doing that, you have to make sure you’re seeing a doctor who follows the procedure put out by the American Board of Chelation Therapy (ABCT).

Chelation pulls out toxic minerals. But no one has yet discovered a chelation material that pulls out toxic metals without pulling out normal metals, too – calcium, magnesium, zinc, and copper, the whole works. The doctors doing the chelation must be reinfusing normal minerals periodically according to his or her reading of the initial chelation test. The initial chelation test on page one shows all the toxic metals that are or not coming out. Page two, which should never be omitted, should always be done. It shows the normal minerals.”

In the meantime, while you’re trying to clear these toxic metal stores to bring the reverse T3 down, opinions are mixed on whether you should be treated with thyroid medication or not. Some believe it’s beneficial to add in regular T3, but if the chelation rectifies your reverse T3 level, then by adding regular T3, you may simply end up with too much free T3. Others recommend waiting until the chelation is done to reevaluate, and if needed, put you on whole thyroid later on, provided you don’t have a family history of autoimmune disease or have Hashimoto’s.

“It simply takes the doctor’s judgment and skill in deciding which way to go,” Dr. Wright says.

Eliminating Heavy Metals Requires Special Care

Clearly, this is a process you’re not going to be able to do by yourself. You really need to have a health coach, a trusted and respected healthcare clinician, who has the capacity to perform these relevant tests and procedures, who can also prescribe the appropriate supplements and thyroid hormone replacement, which you cannot obtain over the counter.

Elimination of carbon-based toxins, such as herbicides and pesticides, can be promoted through sauna-induced sweating. The Hubbard Protocol takes it a step further, and involves the use of niacin, high-intensity exercises, and sauna on a regular basis to help mobilize and eliminate toxins. Unfortunately, sweating doesn’t readily eliminate toxic metals. For those, you need a more aggressive approach, such as chelation.

One option that can help minimize the loss of crucial microminerals is to use chelating suppositories. They will still pull out minerals from your system, but you don’t have to worry about it nullifying the nutritional value of the food you just ate, which is a concern anytime you take an oral chelating agent. One drawback is that it takes a bit longer. “I’ve seen some people who have to do rectal suppository stuff for a couple of years to get all their toxic metals out,” he says. “And yes, we check their normal minerals fairly routinely, every couple of months, just to make sure it’s not being overdone that way.”

Recommended Types of Thyroid Medications

Once your reverse T3 is normalized and any autoimmune issues have been addressed, Dr. Wright goes on to prescribe a thyroid hormone replacement, such as:

  • Armour thyroid
  • Nature-Throid
  • Westhroid

The Armour Thyroid has one disadvantage: despite it being practically a generic now, it costs twice as much as the other two. But unless cost is a major factor, there are several types of tests to check for compatibility, to determine which one is likely to work the best for you.

“We’ve all heard of muscle testing. We don’t have to employ that, but some doctors are very skilled at it,” Dr. Wright says. “We use other sorts of compatibility testing to check for energy flow in the acupuncture meridians and how it’s impaired or not impaired by certain types of thyroid. We’ll go with the one that’s compatible with that individual. But we do respect if people say, ‘Look, I’ve heard that Westhroid and Nature-Throid are half the price of Armour Thyroid. Let’s stick with those if we can.’ We do respect that.”

As for fine-tuning the dose, there are a wide variety of symptoms that can help you gauge whether you’re getting enough of a dose—or help you determine whether you might have a thyroid problem to begin with. To learn more, Dr. Wright suggests picking up Dr. David Brownstein’s book Overcoming Thyroid, Dr. Mark Starr’s book Hypothyroidism Type 2: The Epidemic, or Dr. Ridha Arem’s book The Thyroid Solution. All of these books contain checklists of symptoms to look out for.

If you’re on thyroid hormone replacement, two key signals that you’re taking too much are excessive sweating and rapid heartbeat or heart palpitations. If you get either of those symptoms, you’re getting too much thyroid, and you need to cut back on the dose.

It’s also worth noting that in some cases, if you’re borderline hypothyroid, you may only need an iodine supplement rather than a thyroid hormone replacement. “Some people ask that very question. They’re close enough to normal and they say, ‘I could feel a little better. My test could be a little better. But can I just try some iodine?’ They try and sometimes it succeeds. That’s another option. Sometimes you could normalize with nothing more.”

Treating Overactive Thyroid

At the other end of the spectrum of thyroid dysfunction, you have hyperthyroidism, where your thyroid is overactive. It’s far less common than hypothyroidism, but it’s no less of a problem when it happens. “It’s not common. No. But we should let everybody know that there is an effective treatment out there,” Dr. Wright saysThis is particularly important in light of the conventional treatment options, which are really poor. Typically, you’re looking at using radioactive iodine, which is a disaster, or surgery.

In the video clip above Dr Wright reviews the treatment that originated at Walter Reed Army Medical Center (WRAMC), at their department of thyroid. They had enough people with hyperthyroidism there that they were able to divide them into four treatment groups. One treatment group received lithium. A second group received Lugol’s iodine. Group three took lithium first and then, three or four days later, started iodine. Group four took Lugol’s iodine first, and then three or four days later started taking lithium.

When the statistical dust settled, what they found was that the group that started with Lugol’s iodine and finished with lithium did significantly better than all of the other groups in getting the hyperthyroidism under rapid control. More than two decades ago, The Mayo Clinic also published an article on the treatment of hyperthyroidism using lithium. Here, they used lithium alone, and were also able to bring abnormally high T3 and T4 numbers down to normal within a week to 10 days. It didn’t work on everybody though.

According to Dr. Wright, Walter Reed’s system is profoundly effective. Of all the people treated for hyperthyroidism in Dr. Wright’s clinic, amounting to about 40, there have only been two cases where the protocol failed. Normal levels can often be achieved in less than two weeks. In summary, the treatment is as follows:

  • Patient starts out on five drops of Lugol’s iodine, three times per day
  • After four or five days, patient starts receiving 300 mg of lithium carbonate, one to three times per day

Take Control of Your Thyroid Health

Hypothyroidism is far more prevalent than once thought. Some experts believe that anywhere between 10 and 40 percent of Americans have suboptimal thyroid function. Thyroid hormones are used by every cell of your body to regulate metabolism and body weight by controlling the burning of fat for energy and heat. They’re also required for optimal brain function and development in children. If you feel sluggish and tired, have difficulty losing weight, have dry skin, hair loss, constipation, cold sensitivity, and/or lack of sweating, these could be signs of hypothyroidism.

Iodine is the key to a healthy thyroid, and if you’re not getting enough from your diet (in the form of seafood), you’d be well advised to consider taking a supplement, ideally a high-quality seaweed supplement (be sure to check its source to avoid potential radioactive contamination), or other iodine-containing whole food supplement.


About Hashimoto

Hashimoto’s thyroiditis, also known as chronic lymphocytic thyroiditis, is an autoimmune disease in which the thyroid gland is gradually destroyed.[1] Early on there may be no symptoms.[1] Over time the thyroid may enlarge forming a painless goitre.[1] Some people eventually develop hypothyroidism with its accompanying weight gain, feeling tired, constipation, depression, and general pains.[1] After many years the thyroid typically shrinks in size.[1] Potential complications include thyroid lymphoma.[2]

Hashimoto’s thyroiditis is thought to be due to a combination of genetic and environmental factors.[3] Risk factors include a family history of the condition and having another autoimmune diseases.[1] Diagnosis is confirmed with blood tests for TSH, T4, and antithyroid antibodies.[1] Other conditions that can produce similar symptoms include Graves’ disease and nontoxic nodular goiter.[4]

Hashimoto’s thyroiditis, regardless of whether or not hypothyroidism is present, can be treated with levothyroxine.[1] If hypothyroidism is not present some may recommend no treatment while others may treat to try to reduce the size of the goitre.[1] Those affected should avoid eating large amounts of iodine; however, sufficient iodine is required especially during pregnancy.[1] Surgery is rarely required to treat the goitre.[4]

Hashimoto’s thyroiditis affects about 5% of the population at some point in their life.[3] It typically begins between the ages of 30 and 50 and is much more common in women than men.[1][5] Rates of disease appear to be increasing.[4] It was first described by the Japanese physician Hakaru Hashimoto in 1912.[6] In 1957 it was recognized as an autoimmune disorder.

Managing hormone levels

Hypothyroidism caused by Hashimoto’s thyroiditis is treated with thyroid hormone replacement agents such as levothyroxine, triiodothyronine or desiccated thyroid extract. A tablet taken once a day generally keeps the thyroid hormone levels normal. In most cases, the treatment needs to be taken for the rest of the patient’s life. In the event that hypothyroidism is caused by Hashimoto’s thyroiditis, it is recommended that the TSH levels be kept under 3.0.[21]

Prognosis

Overt, symptomatic thyroid dysfunction is the most common complication, with about 5% of patients with subclinical hypothyroidism and chronic autoimmune thyroiditis progressing to thyroid failure every year. Transient periods of thyrotoxicosis (over-activity of the thyroid) sometimes occur, and rarely the illness may progress to full hyperthyroid Graves’ disease with active orbitopathy (bulging, inflamed eyes). Rare cases of fibrous autoimmune thyroiditis present with severe dyspnea (shortness of breath) and dysphagia (difficulty swallowing), resembling aggressive thyroid tumors – but such symptoms always improve with surgery or corticosteroid therapy. Primary thyroid B cell lymphoma affects fewer than one in a thousand patients, and it is more likely to affect those with long-standing autoimmune thyroiditis.[22]

Epidemiology

This disorder is believed to be the most common cause of primary hypothyroidism in North America; as a cause of non-endemic goiter, it is among the most common.[23] Hashimoto’s thyroiditis affects about 5% of the population at some point in their life.[3] About 1 to 1.5 in 1000 people have this disease at any point in time.[23] It occurs between eight and fifteen times more often in women than in men. Though it may occur at any age, including in children, it is most often observed in women between 30 and 60 years of age.[22] It is more common in regions of high iodine dietary intake, and among people who are genetically susceptible.[22]

History

Also known as Hashimoto’s disease, Hashimoto’s thyroiditis is named after the Japanese physician Hakaru Hashimoto (1881−1934) of the medical school at Kyushu University,[24] who first described the symptoms of patients with struma lymphomatosa, an intense infiltration of lymphocytes within the thyroid, in 1912 in a German publication.[25] The report gave new insight into a condition (hypothyroidism) more commonly seen in areas of iodine deficiency that was occurring in the developed world, and without evident causation by dietary deficiency.

In 1957 it was recognized as an autoimmune disorder and was the first organ-specific one identified.[7]

Pregnancy

Pregnancy challenges thyroid function, putting additional pressure on the organ to function properly. In pregnant women who are positive for Hashimoto’s thyroiditis, this challenge can lead the thyroid either to have decreased functionality or to fail entirely.[26] Pregnant mothers who are at a risk for Hashimoto’s thyroiditis or who have been diagnosed as TPOAb-positive should be aware of the risks to themselves and their fetuses if the disease goes untreated. “Thyroid peroxidase antibodies (TPOAb) are detected in 10% of pregnant women,” which presents risks to those pregnancies.[26] Risk factors are primarily indicated for women whose low thyroid function has not been stabilized by medication. These factors include: low birth weight, neonatal respiratory distress and fetal abnormalities (such as hydrocephalus and hypospadias), miscarriage, and preterm delivery.[26][27] When Hashimoto’s thyroiditis is medicated through levothyroxine replacement, embryo implantation rate and pregnancy outcome are improved.[27] The 2012 study by Lepoutre et al. supports not only treating pregnant women who are TPOAb-positive throughout the entirety of their pregnancies, but their research also strongly recommends universal screening of thyroid levels for pregnant women.[26] They also recommend consistent cooperation between obstetricians and endocrinologists throughout the patient’s pregnancy to ensure a positive outcome.[26] This conclusion is also supported by the research conducted in 2013 by Budenhofer, et al., as well as the 2013 study of Balucan, et al.[28][29] In March 2015, the Endocrine Society clearly stated that it does recommend screening in pregnant women who are considered high-risk for thyroid autoimmune disease.[30]

It is also recommended for undiagnosed women to be tested for thyroid peroxides antibodies if they have ever been pregnant (regardless of birth outcome). In their 2014 study, Carlé, et al. concluded, “…previous pregnancy plays a major role in development of autoimmune overt hypothyroidism in premenopausal women, and the number of previous pregnancies should be taken into account when evaluating the risk of hypothyroidism in a young women [sic].”[31] According to the research conducted by Carlé, et al., risk for thyroid dysfunction as well as for thyroid antibody production increases when at-risk or previously diagnosed mothers have more than one pregnancy.

Gout, Dementia, Chelation Therapy

Gout is an inflammatory condition

It is caused by inflammation in your body, which is linked to metabolic syndrome, a condition characterized by central obesity, hypertension, and disturbed glucose and insulin metabolism. According to medical data, there is a high prevalence of metabolic syndrome among gout sufferers.

Excess body weight

What’s more, excess body weight can exacerbate gout attacks, as it requires extra support. This further irritates your already sensitive nerve endings. It’s not surprising that overweight gout patients are more prone to experience more painful and intense flare-ups. As a matter of fact, obesity can worsen any type of arthritis.

The best thing you can do is to simply lose the weight and keep it off. A 2002 study published in the journal Circulation proves this: researchers studied obese women with metabolic syndrome and found that weight gain, especially around the abdomen, increased the levels of a protein called cytokines in their immune system. Certain cytokines cause an inflammatory response that can contribute to the formation of fatty deposits in arteries (atherosclerosis).

The participants were asked to undergo a one-year program of diet, exercise, and behavioral counseling. At the end of the program, they each lost at least 10 percent of their starting weight, which is an average of about 22 pounds, and also reduced their levels of cytokines and other damaging proteins.4

A bit of thoughtful planning and a few natural lifestyle changes can actually have a significant impact on managing your weight and helping you avoid gout. I’ll discuss more about this later.

Unfortunately, conventional physicians ignore these natural tactics and instead recommend drugs as the “best” option for gout treatment – something that does not address the underlying cause.

Are Drugs Really Necessary to Treat Gout?

Over the years, physicians have been prescribing gout patients with different pharmaceutical drugs, such as:

Non-steroidal anti-inflammatory drugs (NSAIDs) :
Corticosteroids Corticotropin (adrenocorticotropic hormone)
Colchicine Febuxostat Aloprim Zyloprim

Drugs such as NSAIDs cannot actually cure gout

Not only is there NO solid evidence that these drugs can actually cure gout, but they also expose you to many side effects, including extremely dangerous ones.

For example, NSAIDs, one of the most widely prescribed drugs today, are known to cause:

Gastrointestinal upsets including nausea, vomiting, diarrhea, constipation, and decreased appetite Dizziness, headaches, and drowsiness Fluid retention, Rashes Kidney and/or liver failure Shortness of breath, prolonged bleeding after an injury, Ulcers

NSAIDs can also increase your risk of fatal stomach and intestinal reactions, which can occur at any time during your gout treatment and without any apparent symptoms. NSAIDs (except for low-dose aspirin) can also put you at a higher risk of heart attack and stroke.

Gout Drugs

Gout drugs like allopurinol and colchicine work by decreasing crystal formation, lowering your uric acid levels, or blocking your body’s natural inflammatory response. They also have very dangerous long-term effects, and since gout can be a lifelong condition, following conventional advice and taking these drugs for a very long time can potentially wreak havoc on your wellbeing.

The good news is that there are natural anti-inflammatory remedies that can help alleviate gout symptoms. Among these is cayenne cream, also known as capsaicin cream. Derived from dried hot peppers, it alleviates pain by depleting your body’s supply of substance P, a chemical found in nerve cells, which transmits pain signals to your brain.

Here are other holistic pain relief alternatives that I highly recommend:

Boswellia

Boswellia (boswellin or “Indian frankincense”). It contains active anti-inflammatory ingredients that may reduce pain. Krill oil. Animals studies found that its EPA and DHA omega-3 fats have anti-inflammatory properties that reduce joint inflammation and promote joint lubrication. Bromelain. This natural anti-inflammatory is found in fresh pineapples, but can also be taken in supplement form.
Cetyl myristoleate oil (CMO). Found in dairy butter and fish, this acts as a joint lubricant and anti-inflammatory. I use topical CMO to relieve ganglion cysts and a mild annoying carpal tunnel syndrome that pains me whenever I use a non-ergonomic keyboard. Evening primrose, black currant, and borage oils. They contain gamma linolenic acid (GLA), an essential fatty acid that is useful for arthritic pain. Ginger. It’s a natural immune system booster with anti-inflammatory and pain-relieving properties. You can eat it fresh or seep it to make delicious ginger tea.

These are wonderful natural remedies with anti-inflammatory properties that are ideal not only for gout, but also for chronic pain and other types of arthritis, like rheumatoid arthritis and osteoarthritis.

Lower protein diet for Gout

DNA and RNA contain purines that are the primary building blocks of our genetic code. Meat- eating causes large quantities of purines to break down and form uric acid. Uric acid causes gout and kidney stones.  Both these ailments are cured with a lower-protein diet.

Growth hormones, faster aging

I also believe the heavy use of growth hormone in intensive farming and increasing amounts of environmentally toxic synthetic chemicals and endocrine mimickers, such as organochlorines— also known as gender benders—will be shown to be contributing to the trend of faster aging.

Aluminum and Dementia

Sources of exposure: Aluminum cookware, aluminum foil, antacids, antiperspirants, baking powder (aluminum containing), buffered aspirin, canned acidic foods, food additives, lipstick, medications and drugs (anti-diarrheal agents, hemorrhoid medications, vaginal douches), processed cheese, “softened” water, and tap water.

Target tissues: Bones, brain, kidneys and stomach.

Signs and Symptoms: Colic, dementia, esophagitis, gastroenteritis, kidney damage, liver dysfunction, loss of appetite, loss of balance, muscle pain, psychosis, shortness of breath, and weakness.

The highest aluminum exposure is frequently due to the chronic consumption of aluminum- containing antacid products187. Research shows that aluminum builds up in the body over time; thus, the health hazard to older people is greater.

D.R. McLaughlin, M.D., F.R.C.P. (C), professor of physiology and medicine and director of the Centre for Research in Neurodegenerative Diseases at the University of Toronto, states, “Concentrations of aluminum that are toxic to many biochemical processes are found in at least ten human neurological conditions.”188  Recent studies suggest that aluminum contributes to neurological disorders such as Alzheimer‘s disease, Parkinson‘s disease, senile and pre-senile dementia, clumsiness of movements, staggering when walking, and inability to pronounce words properly. Behavioral difficulties among schoolchildren have also been correlated with elevated levels of aluminum and other neurotoxic heavy metals.

Arsenic

Sources of exposure: Air pollution, antibiotics given to commercial livestock, certain marine plants, chemical processing, coal-fired power plants, defoliants, drinking water, drying agents for cotton, fish, herbicides, insecticides, meats (from commercially raised poultry and cattle), metal ore smelting, pesticides, seafood (fish, mussels, oysters), specialty glass, and wood preservatives.

Target tissues: Most organs of the body, especially the gastrointestinal system, lungs, and skin.

Signs and Symptoms: Abdominal pain, burning of the mouth and throat, cancer (especially lung and skin), coma, diarrhea, nausea, neuritis, peripheral vascular problems, skin lesions, and vascular collapse.

The greatest dangers from chronic arsenic exposure are lung and skin cancers and gradual poisoning, most frequently from living near metal smelting plants or arsenic factories.

Cadmium

Sources of exposure: Air pollution, art supplies, bone meal, chocolate (non-organic), cigarette smoke, food (coffee, fruits, grains, and vegetables grown in cadmium-laden soil, meats [kidneys, liver, poultry], or refined foods), freshwater fish, fungicides, highway dusts, incinerators, mining, nickel-cadmium batteries, oxide dusts, paints, phosphate fertilizers, power plants, seafood (crab, flounder, mussels, oysters, scallops), sewage sludge, “softened” water, smelting plants, tobacco and tobacco smoke, and welding fumes.

Target tissues: Appetite and pain centers (in brain), brain, heart and blood vessels, kidneys, and lungs.

Signs and Symptoms: Anemia, dry and scaly skin, emphysema, fatigue, hair loss, heart disease, depressed immune system response, hypertension, joint pain, kidney stones or damage, liver dysfunction or damage, loss of appetite, loss of sense of smell, lung cancer, pain in the back and legs, and yellow teeth.

Current studies are attempting to determine if cadmium-induced bone and kidney damage can be prevented (or made less likely) by adequate calcium, protein (amino acids), vitamin D, and zinc in the diet.

Lead

Sources of exposure: Air pollution, ammunition (shot and bullets), bathtubs (cast iron, porcelain, steel), batteries, canned foods, ceramics, chemical fertilizers, chocolate (non-organic), cosmetics, dolomite, dust, foods grown around industrial areas, gasoline, hair dyes and rinses, leaded glass, newsprint and colored advertisements, paints, pesticides, pewter, pottery, rubber toys, soft coal, soil, solder, tap water, tobacco smoke, and vinyl ‗mini-blinds‘.

Target tissues: Bones, brain, heart, kidneys, liver, nervous system, and pancreas.

Signs and Symptoms: Abdominal pain, anemia, anorexia, anxiety, bone pain, brain damage, confusion, constipation, convulsions, dizziness, drowsiness, fatigue, headaches, hypertension, inability to concentrate, indigestion, irritability, loss of appetite, loss of muscle coordination, memory difficulties, miscarriage, muscle pain, pallor, tremors, vomiting, and weakness.

The toxicity of lead is widely acknowledged. The greatest risk for harm, even with only minute or short-term exposure, is to infants, young children, and pregnant women. A federal study conducted by the Centers for Disease Control and Prevention (CDCP) in 1984 estimated that three to four million American children have an unacceptably high level of lead in their blood. Dr. Suzanne Binder, a CDCP official, stated, “Many people believed that when lead paint was banned from housing [in 1978], and lead was cut from gasoline [in the late 1970s], lead- poisoning problems disappeared, but they‘re wrong. We know that throughout the country children of all races, and ethnicities and income levels are being affected by lead [already in the environment].” In their book, ‗Toxic Metal Syndrome‘, Dr.‘s R. Casdorph and M. Walker report that over 4 million tons of lead is mined each year and existing environmental lead levels are at least 500 times greater than pre-historic levels.

In 1989, the U.S. Environmental Protection Agency (EPA) reported that more than one million elementary schools, high schools, and colleges are still using lead-lined water storage tanks or lead-containing components in their drinking fountains. The EPA estimates that drinking water accounts for approximately 20% of young children‘s lead exposure.189 Other common sources are lead paint residue in older buildings (as in inner cities) and living in proximity to industrial areas or other sources of toxic chemical exposure, such as commercial agricultural land. All children born in the U.S. today have measurable traces of pesticides, a source of heavy metals and chlorine-based chemicals, in their tissues.

The American Environmental Safety Institute purchased a wide array of popular, readily available chocolate products from retail stores in Los Angeles, and sent them unopened to a widely recognized and well regarded analytical laboratory, which used standard research techniques to document the presence of the toxic metals lead and cadmium in 68% of the chocolate products tested. Significant levels of lead were found in a wide array of chocolate products (including syrup/toppings, milk chocolate products, dark chocolate products, and chocolate products that contain nuts, rice and other ―inclusions‖), with the levels ranging as high as 0.105 parts-per-million (―ppm‖), 67 times as high as the lowest amount of 0.00157 ppm.

Similarly, cadmium levels in chocolate products vary significantly as well, with the observed levels starting at 0.00215 ppm and ranging up to 0.136 ppm – here the higher level is 63 times the lower level.190

(Sam Bock‘s Note: Hair samples of myself, my nieces and nephews, and others who were all eating higher amounts of chocolate all showed high lead and cadmium levels in their hair. My hair levels returned to normal once discontinuing the non-organic chocolate.)

Lead is a known neurotoxin (kills brain cells), and excessive blood lead levels in children have been linked to learning disabilities, attention deficit disorder (ADD), hyperactivity syndromes, and reduced intelligence and school achievement scores.

Nickel

Sources of exposure: Appliances, buttons, ceramics, cocoa, cold-wave hair permanent, cooking utensils, cosmetics, coins, dental materials, food (chocolate, hydrogenated oils, nuts, food grown near industrial areas), hair spray, industrial waste, jewelry, medical implants, metal refineries, metal tools, nickel-cadmium batteries, orthodontic appliances, shampoo, solid-waste incinerators, stainless steel kitchen utensils, tap water, tobacco and tobacco smoke, water faucets and pipes, and zippers.

Target tissues: Areas of skin exposure, larynx (voice box), lungs, and nasal passages.

Signs and Symptoms: Apathy, blue-colored lips, cancer (especially lung, nasal, and larynx), contact dermatitis, diarrhea, fever, headaches, dizziness, gingivitis, insomnia, nausea, rapid heart rate, skin rashes (redness, itching, blisters), shortness of breath, stomatitis, and vomiting.

The greatest danger from chronic nickel exposure is lung, nasal, or larynx cancers, and gradual poisoning from accidental or chronic low-level exposure, the risk of which is greatest for those living near metal smelting plants, solid waste incinerators, or old nickel refineries.

Mercury

Sources of exposure: Air pollution, batteries, cosmetics, dental amalgams, diuretics (mercurial), electrical devices and relays, explosives, farmed fish (salmon, trout, char, etc.), foods (grains), fungicides, fluorescent lights, freshwater fish (especially large bass, pike, and trout), insecticides, mining, paints, pesticides, petroleum products, saltwater fish (especially large halibut, shrimp, snapper, and swordfish), shellfish, and tap water.

Target tissues: Appetite and pain centers in the brain, cell membranes, kidneys, and nervous system (central and peripheral).

Signs and Symptoms: Abnormal nervous and physical development (fetal and childhood), anemia, anorexia, anxiety, blood changes, blindness, blue line on gums, colitis, depression, dermatitis, difficulty chewing and swallowing, dizziness, drowsiness, emotional instability, fatigue, fever, hallucinations, headache, hearing loss, hypertension, inflamed gums, insomnia, kidney damage or failure, loss of appetite and sense of smell, loss of muscle coordination, memory loss, metallic taste in mouth, nerve damage, numbness, psychosis, salivation, stomatitis, tremors, vision impairment, vomiting, weakness, and weight loss.

Farmed fish, contaminated wild fish, and fish oil supplements, are primary sources of mercury.

Another source of exposure to mercury is “silver” dental fillings (approximately 50% mercury when placed); over 225 million Americans have these fillings in their teeth. Mercury fillings release microscopic particles and vapors of mercury every time a person chews. Vapors are inhaled while particles are absorbed by tooth roots, mucous membranes of the mouth and gums, and the stomach lining.

In people with mercury amalgam fillings, measurements of the mercury level in the mouth ranges between 20 and 400 mcg/m3. Keep in mind that this is continuous exposure. The National Institute of Occupation Safety and Health places the safe limit of environmental exposure to mercury at 20 mcg/m3, but that is assuming a weekly exposure of 40 hours (the work week) and the mercury involved is outside the body. The Environmental Protection Agency‘s allowable limit for continuous mercury exposure is 1 mcg/m3 but, again, that is based on mercury sources outside the body. Neither figure addresses 24-hour-a-day exposure from mercury in one‘s mouth.

Hal Huggins, D.D.S., a specialist in the effect of mercury amalgams on health, reports that 90% of the 7,000 patients he tested showed immune system reactivity from exposure to low levels of mercury. In 1984, the American Dental Association (ADA), without providing scientific evidence, claimed that only 5% of the U.S. population is reactive to mercury exposure, and that this figure is insignificant. Meanwhile, the ADA mandates that dentists alert all dental personnel to the potential hazards of inhaling mercury vapors.

The Environmental Protection Agency (EPA) goes further, instructing dentists to treat mercury amalgam as a toxic material while handling before insertion, and as toxic waste after removal. 191

Mark S. Hulet, D.D.S., who conducts research on amalgam fillings, wrote a pamphlet for his patients, in which he cites five categories of pathological reaction to mercury fillings, as identified by dentists, doctors, and toxicologists. The categories are:

  • Neurological: emotional manifestations (depression, suicidal impulses, irritability, inability to cope) and motor symptoms (muscle spasms, facial tics, seizures, multiple sclerosis)
  • Cardiovascular problems: nonspecific chest pain, accelerated heartbeat
  • Collagen diseases: arthritis, bursitis, scleroderma, systemic lupus erythematosis
  • Immune system diseases: compromised immunity
  • Allergies: Airborne allergies, food allergies, and “universal”

 

One of the keys to mercury‘s effects on health may be its ability to block the functioning of manganese, a key mineral required for physiological reactions in all five categories, notes Dr. Hulet.192

Evidence of Mercury Toxicity in Children with Autism

 In recent years there has been a great deal of controversy regarding the possible role of mercury as a causal agent in the current worldwide epidemic of autism. While the scientific and legal issues will not be settled for some time, there are many autistic children who need help now.

The Autism Research Institute has been evaluating various biomedical treatments of autism since 1967. One approach has been simply to have parents rate the effectiveness of each of the biomedical treatments they have tried. Over 23,000 parents have responded to its questionnaires. Of the 77 biomedical interventions rated for efficacy by parents (see www.AutismResearchInstitute.com, select Parent Ratings of Treatments), mercury detoxification received a far higher rating than any drug, supplement, or special diet.  Mercury detoxification was rated helpful by 73% of parents, with the gluten/casein-free diet coming in second with 63%.  A remarkable and encouraging finding that should not be ignored.

During the last several years, there has been growing clinical and scientific evidence that most children with autism suffer from mercury/metal toxicity.194 Briefly, the evidence shows that children with autism have low levels of glutathione and cysteine (the pre-cursor to glutathione), which is the major pathway for removal of toxic metals like mercury.

The children also often had excessive use of oral antibiotics, which greatly inhibits excretion of mercury. Due to their limited ability to excrete mercury, they have low levels in baby hair (an excretory tissue), high levels in baby teeth, and higher excretion when given DMSA (a chelating agent discussed in detail below) compared to controls.195 The symptoms of autism are consistent with that of mercury toxicity. The epidemiology studies are mixed, but several published studies show a strong link between autism and thimerosal in vaccines.  Overall, it appears that most children with autism suffer from mercury toxicity, and may potentially benefit from detoxification therapy. Furthermore, there have been many reports from physicians and parents that removal of mercury and other toxic metals can be very beneficial to children with autism, sometimes resulting in a major decrease in autistic symptoms.196

In February 2005, the Autism Research Institute published its Consensus Position Paper: Treatment Options for Mercury/Metal Toxicity in Autism and Related Developmental Disabilities (See Appendix A for more details on mercury toxicity, and see Appendix B for more details on the strong evidence of mercury toxicity in children with autism).

This paper contains one of the best discussions I have read of various chelation techniques (discussed in greater detail below).  http://www.autismwebsite.com/ari/vaccine/heavymetals.pdf It is a must read for any patient or doctor considering the use of various chelation detoxification methods. It discusses the pros and cons of a wide variety of detoxifying agents and protocols that have been used and are available. Overall, the consensus position of the Autism Research Institute is that removal of mercury and other toxic metals is one of the most beneficial treatments for autism and related disorders.197 More research is needed, but effective treatments are available now. Each child is an individual, so this report presents general guidelines rather than specific recommendations.

Preventing Toxic Metal Accumulation

 Logic would dictate that once the potential harm from heavy metals is understood, their production and use should be phased out and toxic storage heavily regulated. However this is not happening.

And even if all heavy metal production were to stop today, enough heavy metals have been released into our environment to cause chronic poisoning and numerous neurological diseases for generations to come. There are presently 600,000 toxic waste contamination sites in the United States alone, according to the U.S. Congressional Office of Technology Assessment. Of these,

less than 900 have been proposed by the EPA for Superfund cleanup and approximately 19,000 others are under review.198 While some of these toxic messes were likely caused by accidents or ignorance, the majority came from illegal dumping by hazardous product or waste distributors, manufacturers, transportation companies, or waste management companies. Such practices have not ceased, as focus on profit continues to override concerns about health, the environment, and a more promising future for all of our children.

With the government moving very slowly to protect the public from the hazards of heavy metals, it is up to individuals to take measures to protect themselves.

Removing Toxic Metal Accumulation with Chelation Therapy

 According to many in conventional medicine, there is nothing a person can do to address aluminum, arsenic, cadmium, lead, mercury, or nickel exposure, aside from avoiding known sources.  Given the prevalence of these toxins in our lives, luckily this isn‘t the case.

Fortunately, there are several ways to get these harmful substances out of the body, some of which work faster than others. Various detoxification protocols, specific nutritional therapies, and intravenous and oral chelation therapies all can remove heavy metals and chemical toxins and reduce the toxic load our bodies.

As discussed above, chelating agents are substances which can chemically bond with, or chelate, metals, minerals, or chemical toxins found in the body. Many chelating agents are found in large quantities in healthy foods and help to keep our bodies free of problematic metal build-u

Certain nutrients in food, as well as synthetic agents such as EDTA and other listed below, can be used to accelerate transport of metals out of the body. They do so by electro-chemically binding to a mineral more strongly than other substances in your tissues that may be currently binding such metals to your tissues. (For example a powerful chelating agent can bind to metastatic calcium which may be bound to fat and other substances causing a build up of fatty arterial plaque associated with heart disease and mental decline.)

The chelator binds to, or ―traps‖ a mineral, or metal ion, whether its trapped in arterial plaque, floating in serum, or deep within our cellular tissues. The chelator and its metal is then carried out of the body via the urine and feces. Many organic acids found in the body or in foods act as chelating agents, including acetic acid, ascorbic acid (vitamin C), citric acid, and lactic acid.

Natural chelation processes in the body are responsible for such things as the digestion, assimilation, and transport of food nutrients, the formation of enzymes and hormones, and detoxification of toxic chemicals and metals.

The following sections describes various synthetic the chelating compounds, and how they are used properly.  This section should be read very carefully by anyone considering their use.

Chelation therapy with EDTA was first developed as a method of treating heavy metal poisoning and was introduced into medicine in the United States in 1948 as a treatment for the lead poisoning of workers in a battery factory. Shortly thereafter, the U.S. Navy advocated chelation for sailors who had absorbed lead while painting government ships and facilities. The FDA subsequently approved IV EDTA chelation as a treatment for lead poisoning.

Various methods of chelation therapy have developed over the past 60 years. This range of techniques, most of which are discussed to some extent below, provide the most advanced and effective way to rid the body of harmful metals that are interfering with normal metabolism.

Physicians administering chelation therapy for lead toxicity observed that patients who also had atherosclerosis (fatty-plaque buildup on arterial walls) or arteriosclerosis (hardening of the arteries) experienced reductions in both conditions after chelation. (In this application, as discussed briefly above, the chelator (EDTA in this case) is being used to bind to metastatic calcium, the problematic form of calcium which binds to fats and causes an accumulation of hardened plaque.)  Since 1952, IV EDTA chelation has been used to treat cardiovascular disease.

However, it fell into medical political disfavour apparently because it was relatively inexpensive and threatened vested financial interests. As research has continued to emerge showing the benefits of properly applied chelation therapy, an increasing number of physicians are using this therapy for various uses described further below.  More than 1 million people have received some 20 million EDTA infusions with no serious or lasting side effects.200   Nobel Prize winning chemist Dr. Linus Pauling wrote the forward of Dr. Elmer Cranton‘s research text on EDTA therapy and said ―EDTA chelation therapy makes good sense to me as a chemist and medical researcher. It has a rational scientific basis, and the evidence for clinical benefit seems to be quite strong.‖

There have been so many successes with chelation therapy in treating cardiovascular disease, that the United States National Institute of Health has set up a large 5 year study to determine the merits of EDTA treatment for cardiovascular disease.

I‘m not convinced that this study will open the door for the FDA to endorse the treatment of cardiovascular disease with EDTA, or any other chelating agents, as political forces can be more powerful than science, both in the United States and elsewhere in the world.

While powerful and effective chelation products are available on the internet, any chelation program should only be administered by a health professional, after the appropriate metabolic testing has shown heavy metal poisoning.  This research and other resources provided here can be presented to your doctor, or used by the reader to understand various options available should metabolic testing show you to be overly contaminated with heavy metals; should you be looking to remove metal-based plaque from your arteries, brain and other tissues; or should you be looking for alternatives to potential by-pass surgery.

More than 90% of the 100+ clients I have tested have overly high levels of at least one toxic metal in there bodies. That said, we have been very successful in lowering such toxic loads through various strategies each time the client has chosen to act upon the problem.

The fastest chelation therapies use powerful agents such as EDTA, DMSA, DMPS, or TTFD to bind tightly to heavy metals and transport them out of the body, generally through the urine. (A drawback to EDTA chelation therapy is that it does not bind with mercury.) The administration of chelating agents can be by mouth (orally), by intravenous drip, or by injection depending on the chelating agent and therapeutic goal.

Various foods and other substances in the body are also very effective chelators. Examples of chelating nutrients in foods are Vitamin C (Ascorbic Acid), Vitamin E, certain bioflavonoids, cilantro, coenzyme Q10, garlic, L-cysteine, flax oil, L-glutathione, lipoic acid, methionine, selenium, sodium alginate, zinc gluconate, malic acid, lithium, and many other substances.

Other nutrients like lecithin will help to emulsify (or disperse) problematic build-ups of fat that maybe accumulating in arteries or elsewhere.

In addition to the effectiveness of IV EDTA chelation therapy in treating cardiovascular disease and heavy metal toxicity, research has also documented its benefits for aneurysm, Alzheimer‘s disease and senile dementia, arthritis, autoimmune conditions, cancer, cataracts, diabetes (as seen in the photos at the beginning of this paper), emphysema, gallbladder stones, hypertension, kidney stones, Lou Gehrig‘s disease, osteoporosis, Parkinson‘s disease, scleroderma, stroke, varicose veins, venomous snake bite, and other conditions involving an interruption in blood flow and diminished oxygen delivery.

To learn more about natural chelators and emulsifiers in our foods and bodies, please see Everything You Should Know about Chelation Therapy, by Dr. Morton Walker, D.P.M. and Dr. Hitendra H. Shaw, MD. It and Walker‘s earlier book The Chelation Way are comprehensive looks a many different chelators and there affects on various health problems, from heart disease to dementia. The link below connects you with these books. http://www.amazon.com/gp/product/0879837306/103-8905086- 5990225?%5Fencoding=UTF8&v=glance&n=283155

Source: http://www.paragonsciences.com/genetics.pdf

Potassium for weight loss

potassium

Potassium is an essential macromineral in human nutrition with a wide range of biochemical and physiological roles. It is important in the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, the production of energy, the synthesis of nucleic acids, the maintenance of intracellular tonicity, and the maintenance of normal blood pressure.

In 1928, it was first suggested that high potassium intake could exert an anti-hypertensive effect. Accumulating evidence suggests that diets high in potassium may be protective not only against hypertension, but also strokes and cardiovascular disease and possibly other degenerative diseases, as well.

(Sam Bock‘s Note: Excess potassium in the bloodstream is potentially lethal. This is why potassium supplements are usually sold in single doses of 99mg or less. But individual higher dosages may be required for people with potassium deficiency (diarrhea, elderly). People requiring higher amounts of potassium should spread dosages during the day and take it with food.)

Potassium is a metallic element with atomic number 19 and an average atomic weight of 39.09 daltons. Its symbol is K. It is an alkali metal and belongs to the same group as lithium, sodium, rubidium, cesium and francium. The only non-alkali element that it shares some similarities with is thallium. The thallous cation is similar in size to the potassium cation, which is the basis of the use of thallium for myocardial perfusion imaging. The thallous cation is considered a potassium cation analogue.

Potassium exists physiologically in its univalent cationic state. It is the principal intracellular cation with an intracellular concentration of about 145 milliequivalents or millimoles per liter. This is 30 to 40 times greater than its extracellular concentration, which is normally 3.5 to 5.0 milliequivalents or millimoles per liter. About 98% of the body’s potassium is in intracellular fluid.

Potassium is lost via the alimentary tract or kidneys

The major cause of potassium deficiency is excessive losses of potassium through the alimentary tract or through the kidneys. Potassium depletion typically occurs as a consequence of malnutrition, prolonged use of oral diuretics, from severe diarrhea and from primary or secondary hyperaldosteronism, diabetic ketoacidosis or in those on long-term total parenteral nutrition who have received inadequate potassium.

Signs and symptoms of potassium deficiency include hypokalemia, metabolic alkalosis, anorexia, weakness, fatigue, listlessness and cardiac dysrhythmias. Prominent U-waves are seen in the electrocardiograms of those with hypokalemia.

The intake of potassium in the American diet ranges from about 1,560 to 4,680 milligrams (40 to 120 milliequivalents or millimoles) daily. The potassium intake of vegetarians is at the high end, and even higher in those eating organic food sources. Foods that are rich in potassium are fresh vegetables and fruits.

630 mg of Potassium in a Banana

A medium-size banana supplies 630 milligrams of potassium or about 75 milligrams per inch; a medium orange, 365 milligrams; half a cantaloupe, 885 milligrams; half an avocado, 385 milligrams; raw spinach, 780 milligrams per three to four ounces; raw cabbage, 230 milligrams a cup; raw celery, 300 milligrams a cup. Some vegetable juices supply up to 800 milligrams per serving. A dietary intake of about 3.5 grams of potassium is considered to be a desirable intake of potassium for adults.

Blood pressure reduction

Potassium supplementation has been demonstrated to bring about small but significant reductions in blood pressure in those with mild to moderate hypertension. The mechanism of this effect is unclear. Possible mechanisms for this antihypertensive effect include a decrease in plasma renin activity, effects on resistance vessels related either to a high potassium concentration or to a decrease in the number of angiotensin II receptors and natriuresis (potassium inhibits sodium reabsorbtion in the proximal tubules). (Sam Bock‘s Note: I believe it may be partly tied to potassium‘s role in trans- membrane nutrient and hormone delivery.

Potassium is involved in the uptake of intracellular magnesium

I believe it is somehow involved in the uptake of intracellular magnesium, which while is still not well understood, but increasingly thought to be hormonally controlled, as discussed above. As potassium is required for the proper uptake of hormone by our cells, potassium affects on hormone activity could be affecting magnesium uptake in this manner.)

Potassium intake may prevent stroke

The mechanism by which increased potassium intake may prevent stroke is not known. Possible mechanisms include potassium’s hypotensive effect, inhibition of free radical formation, prevention of vascular smooth muscle proliferation and prevention of arterial thrombosis.

Potassum inhibit free radical formation from macrophages

In in vitro and in animal studies, elevation of extracellular potassium concentration within the physiological range has been shown to inhibit free radical formation from macrophages and endothelial cells, as well as to inhibit proliferation and thymidine incorporation of vascular smooth muscle cells and to reduce platelet sensitivity to thrombin and other agonists.

High potassium diets have also been shown to reduce oxidative stress

High potassium diets have also been shown to reduce oxidative stress on the endothelium of high sodium chloride-fed stroke-prone spontaneously hypertensive rats independent of blood pressure changes.

http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/pot_0208.shtml

Potassium Homeostasis And Clinical Implications

 Am J Med. 1984 Nov 5;77(5A):3-10.                         Related Articles,

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=Display&DB=pubmed

Brown RS.

The clinical estimation of potassium balance generally depends on the level of serum potassium. Since the extracellular fluid contains only 2 percent of the total body potassium, it must be recognized that potassium deficits are usually large before significant hypokalemia occurs, whereas smaller surfeits of potassium will cause hyperkalemia.

The total body potassium is regulated by the kidney in which distal nephron secretion of potassium into the urine is enhanced by aldosterone, alkalosis, adaptation to a high potassium diet, and delivery of increased sodium and tubular fluid to the distal tubule. However, the distribution of potassium between the intracellular and extracellular fluids can markedly affect the serum potassium level without a change in total body potassium.

Cellular uptake of potassium is regulated by insulin, acid-base status, aldosterone, and adrenergic activity.

Hypokalemia, therefore, may be caused by redistribution of potassium into cells due to factors that increase cellular potassium uptake, in addition to total body depletion of potassium due to renal, gastrointestinal, or sweat losses.

Similarly hyperkalemia may be caused by redistribution of potassium from the intracellular to the extracellular fluid due to factors that impair cellular uptake of potassium, in addition to retention of potassium due to decreased renal excretion. An understanding of the drugs that affect potassium homeostasis, either by altering the renal excretion of potassium or by modifying its distribution, is essential to the proper assessment of many clinical potassium abnormalities.

Both hypokalemia and hyperkalemia may cause asymptomatic electrocardiographic changes, serious arrhythmias, muscle weakness, and death. Hypokalemia has also been associated with several other consequences, including postural hypotension, potentiation of digitalis toxicity, confusional states, glucose intolerance, polyuria, metabolic alkalosis, sodium retention, rhabdomyolysis, intestinal ileus, and decreased gastric motility and acid secretion.

The Na+-K+-ATPase (Sodium Pump)

http://arbl.cvmbs.colostate.edu/hbooks/molecules/sodium_pump.html

The Na+-K+-ATPase is a highly-conserved integral membrane protein that is expressed in virtually all cells of higher organisms. (Sam Bock‘s Note: This pump, built of a dynamic and reactive protein that adjusts its function and shape based on various biochemical stimulus, is found in most cell membranes, and uses intracellular bound potassium and extracellular bound sodium to draw nutrients into the cell. Anything interfering with sodium and potassium metabolism, has the potential to seriously disrupt cellular metabolism. )

As one measure of their importance, it has been estimated that roughly 25% of all cytoplasmic ATP is hydrolyzed by sodium pumps in resting humans. In nerve cells, approximately 70% of the ATP is consumed to fuel sodium pumps. As discussed above, ATP is the body‘s primary energy source.  As noted, significant amounts of energy are consumed running these pumps to transport and utilize nutrients. Anything interfering with their function will lead to decreased energy levels.

The gradually falling intracellular potassium levels would slowly crash that person‘s metabolism, by preventing and reducing nutrient and hormone absorption by all of the body‘s potassium dependant cells, causing fatigue, depression, copper build up, and other problems.

The concurrent prevention of magnesium absorption would not only contribute to potential for arrhythmia, and insomnia, but also reduce the body‘s ability to catalyze enzyme function and produce all- important ATP.

A cardiologist can confirm whether palpitations you may experience are of this nature. Such ―unknown causes are usually a result of low intracellular levels of magnesium and potassium. They can often be eliminated by balancing intracellular electrolytes, and by increasing blood oxygen transport levels with dietary increases of essential fatty acids (which will also have a lowering effect on blood pressure).

All minerals must be in balance for your electrolytic salts to also be in balance to allow smooth muscle to function properly. As well, it is very important that the lipids in your bloodstream are conducive to maintaining healthy flexible arteries, and to dissolving any saturated fatty acid build up.

For this we need adequate consumption of essential Omega 3 and Omega 6 GLA fatty acids (see below) in order to maintain proper prostaglandin balance, optimum oxygen transport, and cell membrane flexibility within the cells making up the structural walls of all parts of your cardio-vascular system – heart, lungs, arteries and veins, etc..

Enough B6, B12, folic acid and methyl donors to prevent the buildup of homocysteine (which causes excess oxidation damage and aging of tissues), and adequate levels of Vitamin A, B complex, C, D, E, synergistic minerals and amino acids (protein building blocks) to ensure the regeneration of damaged tissues, and transport of harmful substances from the body.

Adequate levels of cysteine are required to remove and transport metastatic calcium out the plaque that can build up on artery walls.

It has many important actions in the body. Potassium can improve blood pressure, fatigue, stress, and headaches, and glucose transfer which affects weight. It helps to maintain proper electrolyte balance in body cells, is essential for proper muscle function, and is instrumental in conducting nerve impulses.
People also ask

Three Ways Potassium Helps You Lose Weight

 Rating: 5 – ‎Review by Jeanette Beard

Bigger, stronger muscles burn more calories. It prevents excess fluid retention:As an electrolyte, potassium combines with sodium help regulate fluids around your cells and keep you from retaining too much water. This is important because at any given time, you may be holding on to three to five poundsof water weight.

Potassium Benefits for Dieting – Lindora Clinic

http://www.lindora.com › FAQs › Medications

It has many important actions in the body. Potassium can improve blood pressure, fatigue, stress, and headaches, and glucose transfer which affects weight. It helps to maintain proper electrolyte balance in body cells, is essential for proper muscle function, and is instrumental in conducting nerve impulses.

Does Potassium Aid in Weight Loss? | LIVESTRONG.COM

https://www.livestrong.com › Weight Management

Jul 18, 2017 – Electrolytes such as potassium have many important roles in the human body. Not getting enough potassium can cause you to feel tired and worn down, making it harder for you to stay active enough to lose weight effectively. Although supplemental potassium on its own won’t aid weight lossdirectly, it can …

Discover how potassium can help you lose weight and become healthy

gethealthygethot.com › Diet & Nutrition

Potassium is a major electrolyte present in every single cell of our body- that should tell you how significant this mineral is to us. Maintaining fluid balance, blood pressure, nerve function, brain function and muscle control are just some of the ways potassium is useful to us. When it comes to weight loss,potassium.

Potassium & weight loss

Consuming adequate amounts of Potassium each day can help us to reduce our risk of developing these diseases and achieve our weight loss goals. This article explains what Potassium is, why we need it, what diseases it helps combat, how it helps with weight loss and how to get more of it into our daily diet.

How Potassium Functions In Weight Loss – 3FatChicks on a Diet …

https://www.3fatchicks.com › Diets › Nutrition Wise

Like calcium and magnesium, potassium is an electrolyte. It is known for facilitating weight loss. HowPotassium Helps with Weight LossPotassium helps you lose weight by converting food into energy and assisting to build muscles. The bigger and stronger your muscles are, the more calories they burn. With a healthy …

How Potassium Can Boost Your Metabolism – Moms Who Think

When is comes to your boosting your metabolism, potassium a dieter’s best friend. Think back to when the New Year’s weight loss resolution was made, then broken and now reinstituted in the frenzy to be ready for the dreaded swim suit season. This yearly cycle…diet-slack off-now really diet like you mean it, has occurred …

8 Signs You’re Not Getting Enough Potassium

Feb 25, 2014 – Potassium is important for muscle strength, nerve functioning, and a healthy cardiovascular system. Watch out for these symptoms of potassium deficiency.

Magnesium and Weight Loss on the HCG Diet – InsideOut Wellness

Aug 20, 2014 – Magnesium can effectively neutralize the effects of stress and the stress chemical cortisol, which signals a metabolic shutdown that makes losing weight almost impossible. Potassium is very important in cellular biochemical reactions and energy metabolism. Potassium functions in carbohydrate metabolism …

Potassium, weight loss and senior womens’ health. – Muscadinex

Mar 28, 2016 – Potassium is the hidden ingredient that can help women increase energy and lose weight. Read about the six health benefits of potassium.

Protein and fat rich foods for Alzheimer’s disease prevention

Alzheimer’s disease

A recent study showed a single protein that can boost memory and prevent Alzheimers’ disease (yahoo health news Dec 22 2015).  In April 2015, Salk.edu also identified a single protein for muscles and brain.

Energy for muscles and brains, the scientists discovered, is controlled by a single protein called estrogen-related receptor gamma (ERRγ). Evans’ research group has previously studied the role of ERRγ in the heart and skeletal muscles. In 2011, they discovered that promoting ERRγ activity in the muscle of sedentary mice increased blood supply to their muscles and doubled their running capacity. ERRγ, they went on to show, turns on a whole host of muscle genes that convert fat to energy.

Source: http://www.salk.edu/news-release/food-for-thought-master-protein-enhances-learning-and-memory/

What can really help in preventing Alzheimer’s disease?

If we can reduce stress which leads to anxiety, lack of sleep and poor appetite, we can concentrate on nourishing our bodies with whole foods rich in good protein and healthy fats and less bad carbs (sugar).  We can also cut the consumption of top 10 meds for anxiety, depression, pain meds and neuro meds, including those meds for Alzheimer’s and Parkinson.

Our environment is rich in  toxic metals, drugs/pain meds//neuro meds, narcotics, alcohol, OTC (over the counter meds/pain pills)  and other toxins that can also contribute to the deterioration of our brain.

Here is a power breakfast ingredients from Dr Mercola:

A Power Breakfast for Your Mitochondria

About 95 percent of the energy your body uses is created by your mitochondria that metabolizes food through a complex series of electron transport chain that ultimately transfer the energy to ATP (adenosine triphosphate).

If you consume more calories than your body can immediately use, there will be an excess of free electrons, which back up inside your mitochondria. These electrons are highly reactive, and they start to leak out of the electron transport chain in the mitochondria. These excess electrons wind up prematurely killing the mitochondria, and then wreak further havoc by damaging your cell membranes and contributing to DNA mutations.

There are many knowledgeable experts who believe mitochondrial dysfunction is one of the keys to accelerated aging and the development of diseases like cancer.

Fasting is one method to strengthen the mitochondria network systems throughout your body, which is why I recommend stopping eating at least three hours (and ideally five or six hours) before you go to bed (which will then give you a sizeable fasting period while you sleep).

Another method to strengthen your mitochondria is to supply a regular flow of ketones, as they’re a magnificent fuel to up-regulate many mitochondrial processes. This is why the foundation of my breakfast is coconut oil, a food rich in fatty acids that are readily converted into ketones.

Coconut Oil: A Breakfast Superstar

Besides being an excellent fuel for your mitochondria, coconut oil is beneficial for your thyroid. It’s also rich in lauric acid, which converts in your body to monolaurin, a monoglyceride capable of destroying lipid-coated viruses such as HIV and herpes, influenza, measles, gram-negative bacteria, and protozoa such as Giardia lamblia.

Its medium-chain fatty acids (MCTs) also impart a number of health benefits, including raising your body’s metabolism and fighting off pathogens. Additionally, coconut oil is beneficial for brain health and may serve as a natural treatment for Alzheimer’s disease.

MCTs, a primary source of ketone bodies, act as an alternate source of brain fuel that can help prevent the brain atrophy associated with dementia. Coconut oil is also easy on your digestive system and does not produce an insulin spike in your bloodstream. But it will give you a quick energy boost.

Make sure you choose an organic coconut oil that is unrefined, unbleached, made without heat processing or chemicals, and does not contain genetically engineered ingredients.

Avocado: One a Day to Keep the Doctor Away

Avocados, which are actually classified as a fruit, are low in fructose and rich in healthy monounsaturated fat (which is easily burned for energy), and research has confirmed the avocado’s ability to benefit vascular function and heart health.

Because they have a very high fat to protein and carb ratio and are loaded with healthy monounsaturated fats, I typically eat two to three of them every day. Avocados are also very high in potassium (more than twice the amount found in a banana), and will help balance your vitally important potassium-to-sodium ratio. They also have a great fat to protein ratio with 21 grams of mostly monounsaturated fat with only 2 grams of protein.

Avocados also provide close to 20 essential health-boosting nutrients, including fiber, vitamin E, B vitamins, and folic acid. Another boon of avocados — they’re one of the safest fruits you can buy conventionally grown, so you don’t need to spend more for organic ones. Their thick skin protects the inner fruit from pesticides.

What Else Makes My Breakfast Recipe so Good for You?

Whole Flaxseeds

Over half of the fat in flaxseeds comes from beneficial plant-based omega-3s (alpha-linolenic acid (ALA). Flaxseeds are also the richest dietary source of lignan precursors). When you consume lignan precursors, bacteria in your gut convert the “plant” lignans into “human” lignans, including enterodiol and enterolactone, which have weak estrogenic activity.

This can be beneficial for women’s health, because if you have naturally high estrogen levels, the weak “estrogens” from lignans may bind to some of your estrogen receptor sites, thereby actually reducing total estrogen activity.

Lignans’ ability to block the effects of estrogen could potentially help reduce the risk of hormone-associated cancers (breast, uterine, ovarian, and prostate), and they may help lower your risk of heart disease as well. Flaxseeds are highly perishable, which is why it’s better to purchase them whole and grind them yourself.

Raw Cacao Nibs

Also known as cacao beans or cocoa beans, cacao is an authentic superfood. It has nearly 400 chemicals most of which are polyphenols. They are naturally high in antioxidants and other natural compounds that are beneficial for cardiovascular health and weight management. If the cacao beans are not roasted, then you have “raw” cacao, which is then crumbled into small bits or “nibs.”

Cacao is what makes chocolate healthy but is best consumed in its raw state freshly ground without any sugar. The problem is though that they are very bitter and need to be integrated with other foods.

I find the Mercola Vegan Chocolate Protein Powder as an excellent masking food that makes them delicious. I find one tablespoon (half a scoop) of our protein powder that only has 1 gram of non-fiber carbohydrate, is enough to make one ounce of freshly ground raw cacao nibs into a delicious drink.

Chia Seeds

Chia seeds are a quick and easy-to-use source of protein, healthy fats, dietary fiber, minerals, vitamins, andantioxidants, all rolled into one neat package. Although they have similar health benefits to flax seeds, chia seeds may soon edge these out because they don’t have to be ground prior to consumption, and they don’t go rancid as quickly either.

Psyllium

Psyllium contains primarily soluble fibers that serve as powerful prebiotics serving to optimize growth of your microbiome which then digest them to short-chain fatty acids like butyrate, propionate, and acetate that are then converted to healthy ketones to feed your tissues.

A report funded by the Council for Responsible Nutrition Foundation (CRNF) found that if U.S. adults over the age of 55 with heart disease took psyllium dietary fiber daily, it could save nearly $4.4 billion a year – and more than $35 billion in cumulative health care costs between 2013 and 2020. 1

Black Sesame Seeds

Sesame seeds are another source of beneficial lignans, and they also contain a wealth of minerals including copper, manganese, magnesium, calcium, phosphorus, iron, zinc, molybdenum, and selenium.

Some regions, such as China, also value black sesame seeds for their purported anti-aging benefits, and they are rich in B vitamins and iron, deficiencies of which have been linked to memory problems, hearing trouble, and even gray hair.

Chocolate Vegan Protein Powder

This is a simple way to add more high-quality protein (and also fiber and plant-based omega-3s) to your diet, it’s suitable for those following vegan or vegetarian diets, and I really enjoy the chocolate flavor as do most of my friends. I use it primarily as a great flavoring agent that has only one gram of non-fiber carbohydrate for the one scoop used in this recipe.

Cinnamon

Rich in essential oil, cinnamon contains active components including cinnamaldehyde, cinnamyl acetate, and cinnamyl alcohol, which account for some of its many therapeutic benefits. I use the Korintje species in this recipe.

Cinnamon is also known to enhance your antioxidant defenses, and it’s been found to kill E. coli and many other bacteria. Its anti-inflammatory compounds help relieve pain and stiffness of muscles and joints due to arthritis. It also helps prevent urinary tract infections, tooth decay, and gum disease, and helps with blood sugar control. Plus, it has a wonderful, warming flavor.

D-Ribose and Acetyl L-Carnitine

Adenosine triphosphate (ATP) is a coenzyme used as an energy carrier in every cell of your body. It’s composed of three major chemical groups, one of which is D-ribose, a five-carbon sugar. As a structural component or building block of ATP, D-ribose is involved in the energy synthesis in your cells.

When you take supplemental D-ribose, the vast majority of it — about 97 percent — is absorbed into your blood and is quickly distributed into the various tissues in your body. Once inside your cells, your body uses the D-ribose to synthesize and restore your ATP to maintain cellular energy levels

Each of these ingredients is beneficial on its own, but when you combine them into one power breakfast, the end result is a phenomenal super-breakfast

 

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2015 Health Books for your health

The New Health Rules

Frank Lipman, MD, and Danielle Claro

Celeb doctor and New York City’s most well-known integrative physician, Frank Lipman, MD, is known for prescriptions that don’t necessarily come from a bottle (like what food goes on your plate or the numbers of hours you sleep). And his new book, The New Health Rules, is a handbag-sized manifesto for living a healthy, cool life. It’s filled with rules (and pretty photos) like why you should break up with bread and the most important yoga pose you should be doing. It’ll go perfectly with your green juice on the way to work.

Yoga For Life

Colleen Saidman Yee

You know her as the glowing, grounded yogi behind Yoga Shanti and your DVD collection, butSaidman Yee was once a wild child, traveling the globe as a fashion model and picking up a bad drug habit along the way. Her first tome tells the story about how she found herself through yoga, started a new chapter, and might be able to help you do the same.

Skin Cleanse

Adina Grigore

Adina Grigore, the founder of Brooklyn-based skin-care line S.W. Basics, made it big in 2014 when her all-natural skin-care line debuted at Target. Now, she’s coming out with a guide on how to switch over your beauty routine from not-so-clean to all-natural. If you’re still stuck on Cetaphil, you might want to pre-order your copy now.

The Healthy You Diet

Dawna Stone

When a career on Wall Street added an extra 40 pounds to her frame, Dawna Stone realized she needed to change something about the way she was eating—and living. After trying a bunch of diets, without any success, Stone created her own. In The Healthy You Diet, Stone, also the founder of Women’s Running magazine, shares her personal struggle with weight and how she got healthy. It’s also a plan to help you eat cleaner, too.

The 30-Second Body: Eat Clean. Train Dirty. Live Hard.

Adam Rosante

The founder of The People’s Bootcamp, Adam Rosante, is known for having a pay-what-you-can workout policy. And with his new book he’s taking that same health-should-be-universal mentality and dishing out simple clean eating tips and advice like why you should ditch your gym membership and work out at home instead. The fast, fun read makes changing your habits feel that way, too.

What the Fork Are You Eating?: An Action Plan for Your Pantry and Plate

Stefanie Sacks

Your favorite granola might be labeled “natural,” but is it really? Culinary nutritionist Stefanie Sacks, MS, CNS, CDN, wants to help you figure that out. So the master label-reader devoted an entire book to the topic. In What the Fork Are You Eating?: An Action Plan for Your Pantry and Plate (a title you’ve gotta love), the author explains what’s hiding in your food—cough, cough, hidden preservatives—and gives you a solid roadmap for navigating the grocery store, along with a bunch of healthy recipes.

Happy is the New Healthy

Dave Romanelli

The eternal optimist Dave Romanelli shares 31 ways to relax—like spending one minute on love every day and remembering to laugh—in his new book Happy is the New Healthy. We suggest keeping this sunshine-y tome at your desk, so you can pick it up at work in a stressful pinch.

Body of Truth: How Science, History, and Culture Drive Our Obsession with Weight—and What We Can Do about It

Harriet Brown

As a culture, we’re obsessed with weight, says Harriet Brown, a journalist and professor who’s looked deeply into our national body image problem with Body of Truth. She shares her findings on how science, psychology, and the media have had a huge affect on the way we perceive ourselves—and what we can do to change that negative thinking. It’s a must-read whether you’re the most confident woman in the room (or bikini) or can’t remember the last time you had a nice thought about your body.

The Adrenal Reset Diet

Your adrenal glands, which sit on top of your kidneys, regulate adrenaline and cortisol levels (AKA the stress hormones). When they’re taxed, due to stress, being a workaholic, or overachiever, you can experience depleted energy, dark under-eye circles, and it throws off other key things—like your diet, sleep, and menstrual cycle. The Adrenal Reset Diet is designed to help you reduce your stress and cortisol levels with whole foods (using carbs and proteins in a balancing cycle and reducing your sugar and insulin). Actually, a clean diet that helps reduce stress is probably something we all need.

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Email motherhealth@gmail.com your book suggestions for 2015 and 2016. Better yet, collaborate with Connie for a health ebook for 2016.

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