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Protein network linked to cancer is critical to male fertility

This confocal microscope image from a study in the Oct. 18 online edition of Cell Reports shows spermatocytes in mice deficient for a Fanconi anemia pathway protein, Fancd2. The study from Cincinnati Children’s Hospital Medical Center …more Researchers studying reproductive science identified a network of proteins often linked to cancer as also important to maleContinue reading “Protein network linked to cancer is critical to male fertility”

Finding your diagnosis in the brave new world of genetics-based medicine

By John Hewitt report A 3D structure of PLP1 protein (Medical Xpress)—We’ve done a number of articles recently about some amazing individuals developing personalized treatments to their own currently uncurable disease. Whether it is a rare orphan disease like Sanfilippo Syndrome and Castleman Disease, or something more common like cancer, these patients have been ableContinue reading “Finding your diagnosis in the brave new world of genetics-based medicine”

Cheaper Leukemia Testing Breakthrough

Researchers with a sample card with dried blood that can be used to test for chronic myeloid leukemia.CreditRobert Hood/Fred Hutch News Service A rare but treatable form of cancer can now be diagnosed cheaply and easily with dried blood spots instead of whole blood, scientists in Seattle announced last week. The new test for chronicContinue reading “Cheaper Leukemia Testing Breakthrough”

Participate in creating a cancer-free world

Some major medical centers, like Dana Farber, Memorial Sloan Kettering and Vanderbilt, use their own funds and funds from philanthropists to pay for genome sequencing. But then another issue arises, the group told Mr. Biden’s staff. Each medical center keeps its own records of what mutations were found, what drugs were tried and how theContinue reading “Participate in creating a cancer-free world”

REST is lost in mild cognitive impairment and Alzheimer’s disease

Human neurons are functional over an entire lifetime, yet the mechanisms that preserve function and protect against neurodegeneration during ageing are unknown. A study shows that induction of the repressor element 1-silencing transcription factor (REST; also known as neuron-restrictive silencer factor, NRSF) is a universal feature of normal ageing in human cortical and hippocampal neurons.Continue reading “REST is lost in mild cognitive impairment and Alzheimer’s disease”

Common Prostate Cancer Treatment Linked to Later Dementia

Summary: Men with prostate cancer who are treated with testosterone lowering drugs are almost twice as likely to develop dementia within 5 years as those with the same cancer who are treated with different therapies, a new study reports. Source: Stanford. A new retrospective study of patient medical records suggests that men with prostate cancerContinue reading “Common Prostate Cancer Treatment Linked to Later Dementia”

Cancer costs $895 billion annually, Vit D from sun as anti-cancer

Cancer costs $895 billion annually. Comparatively, heart disease costs $753 billion. Nothing else comes close, with traffic accidents and diabetes each costing about $204 billion. “The price for one year of life increased to $139,100 in 2005 and $207,000 in 2013.” The biggest financial impact is in terms of loss of life and productivity, inContinue reading “Cancer costs $895 billion annually, Vit D from sun as anti-cancer”

A DNA Ultra-sensitive test for cancers, HIV

Catching a disease in its earliest stages can lead to more effective therapies. Stanford chemists have increased the likelihood of detecting these diseases via a test that is thousands of times more sensitive than current diagnostics. BY BJORN CAREY A common theme in medicine is that detecting a disease early on can lead to moreContinue reading “A DNA Ultra-sensitive test for cancers, HIV”

Longevity, genes, epigenetics, cancer and disease

Description: The study of human genetic disorders and mutant mouse models has provided evidence that genome maintenance mechanisms, DNA damage signaling and metabolic regulation cooperate to drive the ageing process. In particular, age-associated telomere damage, diminution of telomere ‘capping’ function and associated p53 activation have emerged as prime instigators of a functional decline of tissueContinue reading “Longevity, genes, epigenetics, cancer and disease”

Breast Cancer Assessment Tool

https://www.cancer.gov/bcrisktool/Default.aspx Join 25,000 people in helping redefine health with health concierge and precision medicine. https://clubalthea.com/2016/10/14/your-complete-dna-sequence-will-help-shape-the-future-of-medicine/ Breast cancer prevention: Avoid moldy/fungus filled foods, avoid sugar/soda, do 18-hr fast once a month, exercise, take Vit D and C and eat whole foods.

Cell type-specific properties and environment shape tissue specificity of cancer genes

One of the biggest mysteries in cancer research remains why mutations in certain genes cause cancer only at specific sites in the human body. The poor correlation between the expression level of a cancer gene and the tissues in which it causes malignant transformations raises the question of which factors determine the tissue-specific effects ofContinue reading “Cell type-specific properties and environment shape tissue specificity of cancer genes”

Lung cancer, breath tests and DNA sequencing

Breath Tests for Cancer In addition, new screening tools such as genetic sequencing and breath tests for cancer metabolites are on the horizon and could further improve screening accuracy in individual patients. For example, advances in sensor technologies and breath collection methods are paving the way for breath tests that could separate patients with lungContinue reading “Lung cancer, breath tests and DNA sequencing”

Genes and Cancer

How faulty genes lead to cancer Our genes pick up mistakes that occur when cells divide. These mistakes are called faults or mutations and happen throughout our lives. They are caused by the natural processes in our cells, and by various other factors. These include Tobacco smoke Radiation Ultraviolet radiation from the sun Some substancesContinue reading “Genes and Cancer”

Eggplant and apple cider vinegar for skin cancer

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