Summary: A new study suggests the taste or smell of food acts on sensory neurons, which could produce a type of aging hormone. Source: POSTECH. Animals can perceive changes in many environmental factors such as temperature and the taste or smell of foods. This is achieved by specialized nerve cells called sensory neurons. Interestingly, sensoryContinue reading “Sensory Neurons Modulate Aging Hormone”
Category Archives: anti-aging
SCRIB and DISC1 genes and mental disorders, schizophrenia
Summary: A protein called Scribble (SCRIB gene) appears to orchestrate the intracellular signaling process for forgetting, a new study reports. Source: University of Edinburgh. More than one thousand people have had their entire genetic make-up decoded as part of a long-term study to gain insight into why some people’s brains age better than others. ScientistsContinue reading “SCRIB and DISC1 genes and mental disorders, schizophrenia”
REST is lost in mild cognitive impairment and Alzheimer’s disease
Human neurons are functional over an entire lifetime, yet the mechanisms that preserve function and protect against neurodegeneration during ageing are unknown. A study shows that induction of the repressor element 1-silencing transcription factor (REST; also known as neuron-restrictive silencer factor, NRSF) is a universal feature of normal ageing in human cortical and hippocampal neurons.Continue reading “REST is lost in mild cognitive impairment and Alzheimer’s disease”
Mapping Genes That Increase Lifespan
Comprehensive study finds 238 genes that affect aging in yeast cells. Following an exhaustive, ten-year effort, scientists at the Buck Institute for Research on Aging and the University of Washington have identified 238 genes that, when removed, increase the replicative lifespan of S. cerevisiae yeast cells. This is the first time 189 of these genesContinue reading “Mapping Genes That Increase Lifespan”
LEAN DIETS, LONG LIFE, AND THE MITOCHONDRIA
Parkinson’s disease and Mitochondria as the oxygen-consuming power plants of human cells Mitochondrial maintenance is essential for cellular and organismal function. Maintenance includes reactive oxygen species (ROS) regulation, DNA repair, fusion–fission, and mitophagy. Loss of function of these pathways leads to disease. Mitochondria are the oxygen-consuming power plants of cells. They provide a critical milieuContinue reading “LEAN DIETS, LONG LIFE, AND THE MITOCHONDRIA”