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Conscientious people succeed the most

The only major personality trait that consistently leads to success is conscientiousness. 

 “It’s emerging as one of the primary dimensions of successful functioning across the lifespan,” Paul Tough writes in “How Children Succeed.” “It really goes cradle to grave in terms of how people do.” 

Tough says that people who test high in conscientiousness get better grades in school and college, commit fewer crimes, and stay married longer.

They live longer, too, he says. And not just because they smoke and drink less. They have fewer strokes, lower blood pressure, and a lower incidence of Alzheimer’s disease.

There’s a staggering amount of research linking conscientiousness with success. A National Institute of Mental Health study found that conscientious men earn higher salaries. The National Institute on Aging also found thatconscientiousness is linked to income and job satisfaction. Other studies show that conscientiousness is the most important factor for finding and retaining employment. 

How do you know if you’re conscientious? Conscientious people tend to be super organized, responsible, and plan ahead. They work hard in the face of challenges and can control their impulses. 

Psychologists classify conscientiousness is one of the “Big 5” personality traits, with the others being agreeableness, extroversion, neuroticism, and openness to experience. The other traits can predict certain workplace outcomes — extroversion is a great fit for highly social gigs like sales and openness to experience often leads to creativity — but conscientiousness is remarkable for the way it cuts across roles.

Research shows that arriving on time, doing thorough work, and being thoughtful toward your colleagues helps people regardless of their job function or workplace situation. “Being on top of deadlines is almost universally a good thing,” one industrial psychologist told us.

Moreover, within conscientiousness are the narrower traits of self control and “grit,” which University of Pennsylvania  psychologist Angela Duckworth has found to be more integral to children’s scholarly success than IQ. 

Why conscientiousness people are so successful

“Highly conscientious employees do a series of things better than the rest of us,” says University of Illinois psychologist Brent Roberts, who studies conscientiousness.

To start, they’re better at goals: setting them, working toward them, and persisting amid setbacks. If a super ambitious goal can’t be realized, they’ll switch to a more attainable one rather than getting discouraged and giving up. As a result, they tend to achieve goals that are consistent with what employers want. 

Roberts also owes their success to “hygiene” factors. Conscientious people have a tendency to organize their lives well. A disorganized, un-conscientious person might lose 20 or 30 minutes rooting through their files to find the right document, an inefficient experience conscientious folks tend to avoid. Basically, by being conscientious, people sidestep stress they’d otherwise create for themselves.  

Being conscientious “is like brushing your teeth,” Roberts says. “It prevents problems from arising.” 

Conscientious people also like to follow rules and norms. You can spot the conscientious kids in the classroom. They sit in their chairs, don’t complain, and don’t act out — which also, of course, contributes to earning good grades from teachers. While conscientiousness doesn’t correlate with high SAT scores, it does predict high GPAs. 

To spot conscientious people at work, Roberts says to look for punctuality. If someone shows up on time, that’s a great clue toward conscientiousness, since a punctual person has to be organized enough — and care enough — to arrive on time. 

The bigger, and less visible, indicator is how people deal with setbacks. Do they give up and redouble their efforts? 

“The conscientious person is going to have a plan,” Roberts says. “Even if there is a failure, they’re going to have a plan to deal with that failure.”

 

Connie Dello Buono 

 

Money coach and wealth strategist for tax-free retirement

 

 

 

1708 Hallmark Lane San Jose CA 95124
PS. Ask me for 6% index annuities and 13- 17% index universal life policies

Need a used Hybrid car in the bay area

I have been driving for at least 50 miles per day serving families with tax free retirement.  I am looking for a hybrid car to save on gas ( > $4/gal) expense and my Nissan has around 209k in total mileage.  My 20 yr old who is a working student will then use my old Altima although he is not looking forward to driving and being politically correct, he wants to save the planet from pollution of all sorts.

Commuting in the car pool lane helps. I love the feel of Nissan leaf with its style and comfort but I am afraid I will get stranded in the dessert and run out of battery, which takes many hours to charge. I like the Hyundai Sonata for overall use, efficiency and comfort.

I am looking for a used hybrid if anyone can point me to one. Better yet if you want to donate it to either of my two non-profits: Motherhealth Inc and Green Research Institute, I would appreciate it a lot as I help seniors in the bay area access to affordable caregiving and care and education in areas of health and the environment.

We live in a village, wish we can just share resources and not buy more than two houses or cars. I support 12 teens in college as I experienced the same fate when I was a working student and was many times needing financial aid.

I believe in the feeling of giving that brings good health and karma. At the end, we all must live a significant life.

Blessings,

Connie Dello Buono

408-854-1883

motherhealth@gmail.com

1708 Hallmark Lane San Jose CA 95124

PS. Your referral to those who needs a tax free retirement income for life with no market risks and access to funds up to $1.5M when cancer,stroke or disability occur is much appreciated.

Virus attacks cancer cells, healing brain tumors, a research from Duke University scientist

Modified poliovirus used as therapy for glioblastoma

The May 5, 2014 issue of People magazine features Stephanie Lipscomb, the first patient in the world to undergo an investigational therapy at Duke’s Preston Robert Tisch Brain Tumor Center, during which a modified poliovirus was injected into her brain to combat aggressive brain cancer. Two years after undergoing the procedure, Stephanie is doing great.

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DURHAM, N.C. — In a daring yet successful experiment to cure deadly brain tumors, researchers have combined the cancer-killing properties of poliovirus together with a harmless genetic coding element from the common cold. 

The resulting modified virus created a remarkably strong anti-cancer agent that rapidly killed cancer cells in laboratory cell cultures and in animals — and without causing polio, said Matthias Gromeier, M.D., assistant professor of molecular genetics and microbiology at the Duke Comprehensive Cancer Center. Testing of the new viral agent in humans should begin within two years, he said. 

In the study, the modified poliovirus rapidly killed cancer cells derived from primary brain tumors as well as cells derived from breast and colon cancer metastases — all within a matter of four to six hours. In fact, polio is known to be one of the quickest killers of infected host cells, producing approximately a thousand additional infectious viral units per infected cell, he said. 

“We made a drug out of a virus by engineering its destructive abilities from a foe into a friend,” said Gromeier. His most recent results — a collaborative effort with Darrell Bigner, M.D., Henry Friedman, M.D., Allan Friedman, M.D., and John Sampson, M.D., of the Brain Tumor Center at Duke — will be published in the Dec. 9, 2003, issue of the Proceedings of the National Academy of Sciences, which is currently available online. 

The key to Gromeier’s success has been disabling the poliovirus’ ability to kill normal brain cells while retaining its ability to kill cancer cells in the brain. To do so, Gromeier’s team swapped a critical genetic element from the common cold “rhinovirus” with the corresponding genetic element from the poliovirus. The genetic element, called an “IRES” (internal ribosomal entry site), enables a virus to express its own genetic information inside the host cell it has invaded, said Gromeier. 

Gromeier selected the IRES from a rhinovirus because it does not typically infect the human brain. Normal brain cells lack the appropriate environment required for the rhinovirus IRES to begin translating the poliovirus’s genetic information, his study demonstrated. 

Cancer cells, however, regulate gene expression very differently than normal cells do. They grow faster, lack growth inhibitors and generally provide a supportive environment that is highly susceptible to viruses of all sorts, making viruses an excellent invader to disrupt cancer’s growth. 

“In cancer cells, the IRES from rhinovirus acts as the trigger that activates gene expression, but the genes being expressed — the silver bullets in the gun, so to speak — are all from the poliovirus,” said Gromeier. “The polio proteins kill the cancer cells quickly and efficiently.” 

In fact, polio is the perfect virus to attack brain cancer cells because it has a natural affinity for invading the brain, said Gromeier. Polio infects brain cells by binding to a receptor or “docking site” called CD155 on the outside of motor neurons. Gromeier showed that brain tumors over-produce this CD155 receptor, making the cancer cells particularly vulnerable to infection with poliovirus. The modified poliovirus still enters normal motor neurons because it shares the same CD155 receptor as brain tumor cells, but it can no longer grow in normal cells. 

“We have a virus that naturally targets brain cells, but we have replaced the genetic coding element that makes the virus so dangerous,” said Gromeier. “The virus has lost its ability to grow in normal neurons.” 

Tests in mice and in non-human primates have confirmed that the modified poliovirus does, indeed, kill brain tumor cells but does not affect normal motor neurons. Moreover, viruses don’t carry the toxic side effects of chemotherapy and radiation, and viruses can be introduced directly into the tumor. 

“The brain is a very common site of cancer metastasis, but cancer in the brain is extremely difficult to treat,” said Gromeier. “Cancer cells are often interspersed throughout normal brain tissue, and most chemotherapy does not cross the blood-brain barrier, so getting the drug to the target site of treatment is a huge problem clinically.” 

To combat that problem, the modified poliovirus is directly injected into the brain tumor. Once there, the virus seeks out and destroys cancerous cells without detection by the body’s immune system. The immune system would normally neutralize the poliovirus in vaccinated individuals because they have built up antibodies against polio. But the brain does not have immunity against polio because antibodies do not cross the blood-brain barrier. Hence, infusing the brain directly with modified polio is the most effective method of killing cancer cells. 

But giving the modified poliovirus to humans — even to terminal brain cancer patients — requires rigorous testing to understand the mechanism behind its virulence in cancer cells and its impotence in normal brain cells. 

So, Gromeier’s team embarked on a mission to elucidate the molecular mechanism that causes the rhinovirus IRES to function in cancer cells but to malfunction in normal neurons. 

After extensive testing, he discovered that the IRES from the rhinovirus communicates with the opposite end of the poliovirus genome. That distant region, called the 3-prime non-translated region, drives how the virus transmits its genetic instructions inside the host cell. Gromeier’s data suggest that — in cancer cells — the rhinovirus IRES and the 3-prime communicate via a set of proteins, called co-factors, which ignite the IRES to begin functioning. 

Normal motor neurons, however, may not provide the appropriate set of co-factors to stimulate rhinovirus IRES function, said Gromeier. Hence, the modified virus cannot grow in normal motor neurons. 

“Cells differ in terms of how well-suited they are to a particular virus,” said Gromeier. “Every cell type has unique cellular proteins that can either support or block viral function, and we believe differences in these proteins account for the modified virus’ inability to infect normal brain cells.” 

The research was funded by the National Institutes of Health, the National Cancer Institute, The Burroughs Wellcome Fund, ABC2 Foundation, and the Brain Tumor Society.

The reason why I want to succeed

Please tell me what you think of this site, the reason why I am retiring my mom at 78 as a caregiver and more…
Do you know anyone who are not happy with their job, needing a tax free retirement, and a business they can be with for the rest of their lives?
And you are also invited for a free trip to Europe in 2015.
And to hear Tony Robbins on May 17 at the Embassy Suites in Walnut Creek. Door prices and more. Learn tax-free retirement in the morning and ways to earn extra income in the afternoon
Sincerely,
Connie Dello Buono
408-854-1883
motherhealth@gmail.com

High temp meat cooking and Parkinson’s Disease

Parkinson’s disease (PD) is the second most common neurodegenerative disease. Much data has linked the etiology of PD to a variety of environmental factors.

The majority of cases are thought to arise from a combination of genetic susceptibility and environmental factors. Chronic exposures to dietary factors, including meat, have been identified as potential risk factors.

Although heterocyclic amines that are produced during high-temperature meat cooking are known to be carcinogenic, their effect on the nervous system has yet to be studied in depth. In this study, we investigated neurotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), a highly abundant heterocyclic amine in cooked meat, in vitro. We tested toxicity of PhIP and the two major phase I metabolites, N-OH-PhIP and 4′-OH-PhIP, using primary mesencephalic cultures from rat embryos. This culture system contains both dopaminergic and nondopaminergic neurons, which allows specificity of neurotoxicity to be readily examined.

We find that exposure to PhIP or N-OH-PhIP is selectively toxic to dopaminergic neurons in primary cultures, resulting in a decreased percentage of dopaminergic neurons. Neurite length is decreased in surviving dopaminergic neurons. Exposure to 4′-OH-PhIP did not produce significant neurotoxicity.

PhIP treatment also increased formation of oxidative damage markers, 4-hydroxy-2-nonenal (HNE) and 3-nitrotyrosine in dopaminergic neurons.

Pretreatment with N-acetylcysteine was protective. Finally, treatment with blueberry extract, a dietary factor with known antioxidant and other protective mechanisms, prevented PhIP-induced toxicity. Collectively, our study suggests, for the first time, that PhIP is selectively toxic to dopaminergic neurons likely through inducing oxidative stress.

http://toxsci.oxfordjournals.org/content/early/2014/04/25/toxsci.kfu060.abstract.html?papetoc

Join us and hear Tony Robbins on Aug 30 in Walnut Creek CA

If you want to boost your income potential and be strong financially, please join us on Sat in Walnut Creek CA.

Call Connie 408-854-1883 motherhealth@gmail.com

Build your self esteem, your value and your living a significant life.

Life is better when shared.

We all have the same 24 hours but why others are earning more.

There are no excuses to those who want to succeed.

Live life according to your dreams.

We only help you jump start it so you can create happy memories

To last for a lifetime.

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Rollover your 401k and IRA to index annuities and index strategies IUL with Connie, and receive a lifetime service to meet your changing needs.

Connie Dello Buono, CA Life Lic 0G60621
408-854-1833 motherhealth@gmail.com

conniedbuono@gmail.com

1708 Hallmark Lane San Jose, CA 95124

The first USA case of MERS virus was reported today

Image

Middle East Respiratory Syndrome (MERS) is viral respiratory illness first reported in Saudi Arabia in 2012. It is caused by a coronavirus called MERS-CoV. Most people who have been confirmed to have MERS-CoV infection developed severe acute respiratory illness. They had fever, cough, and shortness of breath. About 30% of these people died.

So far, all the cases have been linked to six countries in or near the Arabian Peninsula. This virus has spread from ill people to others through close contact. However, the virus has not shown to spread in a sustained way in communities. The situation is still evolving.

CDC is working with partners to better understand the risks of this virus, including the source, how it spreads, and how infections might be prevented. CDC has provided information for travelers and is working with health departments, hospitals, and other partners to prepare for possible cases in the United States.

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CDC advises that people follow these tips to help prevent respiratory illnesses:

  • Wash your hands often with soap and water for 20 seconds, and help young children do the same. If soap and water are not available, use an alcohol-based hand sanitizer.
  • Cover your nose and mouth with a tissue when you cough or sneeze then throw the tissue in the trash.
  • Avoid touching your eyes, nose, and mouth with unwashed hands.
  • Avoid close contact, such as kissing, sharing cups, or sharing eating utensils, with sick people.
  • Clean and disinfect frequently touched surfaces, such as toys and doorknobs

How Much Do You Know About Retirement? take the test

These questions refer directly to the fifteen factors of retirement success and great variability exists from person to person. Knowledge about retirement is often skimpy and many times imprecise. This questionnaire may raise your awareness of areas you need to pay special attention to in your retirement planning

Directions: Decide whether you believe the statements below are more true or more false.
Mark the false statements with an F, and the true statements with a T.

 

_____ 1. Most workers slow down and become less productive the closer they get to retirement.
_____ 2. Generally the closer people get to their retirement the more apt they are to resist it.
_____ 3. People who direct their lives themselves do better in retirement than those who let others make their decisions for them.
_____ 4. People who are healthy when they retire generally continue in good health well into their retirement years.
_____ 5. The average income of retirees has declined in the last decade due to high rates of inflation.
_____ 6. If you’re happy now before you retire, chances are you’ll be happy when you do retire.
_____ 7. About half the people in retirement report being chronically depressed, lonely, and/or sad.
_____ 8. Men find a more difficult emotional adjustment into retirement than do women.
_____ 9. The most personally satisfied retirees are those who have hobbies, activities, “causes”, or active leisure pursuits.
_____ 10. People who are opinionated and somewhat rigid in their thinking do better in retirement because they know what they want.
_____ 11. People who reminisce a lot tend not to do well in retirement.
_____ 12. When a person has others who are dependent upon him/her either financially or emotionally, they tend to retire earlier rather than later.
_____ 13. A happy marriage/special relationship equals a successful retirement.
_____ 14. Most people retire because they feel themselves getting old.
_____ 15. One of the best ways to genuinely enjoy your retirement is to find suitable replacements for what your job formerly gave you in the way of satisfactions.

Answers:

1) F 2) F 3) T 4) T
5) F 6) T 7) F 8) F
9) T 10) F 11) F 12) F
13) T 14) F 15) T

© 2001 Richard P. Johnson, Ph.D.

 

Retirement Quotations by Women

Retirement

 http://www.quotationsbywomen.com/tag/Retirement/

 

“Live long enough and you’ll come into pensions, a lovely thing. Presents every month from people you didn’t know cared.”

Ruth Gordon, An Open Book (1980)

New Quoatation

“When I retired, I found I had not enough money and too much husband.”

Anonymous, in Helen Foster, It’s Hard to Look Graceful When You’re Dragging Your Feet (1983)

New Quoatation

“Retirement, I feel, means a new adventure in living — not a stopping.”

Marion Hilliard, A Woman Doctor Looks at Love and Life (1957)

New Quoatation

“In retirement, the passage of time seems accelerated. Nothing warns us of its flight. It is a wave which never murmurs, because there is no obstacle to its flow.”

Anne Sophie Swetchine, in Count de Falloux, ed., The Writings of Madame Swetchine (1869)

New Quoatation

“For millions, the retirement dream is in reality an economic nightmare. For millions, growing old today means growing poor, being sick, living in substandard housing, and having to scrimp merely to subsist.”

Sylvia Porter, Sylvia Porter’s Money Book (1975)

New Quoatation

“… I was born and bred an adventurer, with a great zest for change and excitement — and retirement is like prison.”

Diana Cooper, 1950, in Artemis Cooper, ed., The Letters of Evelyn Waugh and Diana Cooper (1992)

New Quoatation

“Retirement revives the sorrow of parting, the feeling of abandonment, solitude and uselessness that is 

caused by the loss of some beloved person.”

Simone de Beauvoir, The Coming of Age (1970)

New Quoatation

“Retirement … may be looked upon either as a prolonged holiday or as a rejection, a being thrown on to the scrap-heap.”

Simone de Beauvoir, The Coming of Age (1970)

New Quoatation

“It’s daring and challenging to be young and poor, but never to be old and poor. Whatever resources of good health, character, and fortitude you bring to retirement, remember, also, to bring money.”

Jane Bryant Quinn, Making the Most of Your Money (1991)

New Quoatation

“… how tedious is retirement! You cannot imagine to yourself the monotony with which day comes after day.”

Agatha Christie, The Murder of Roger Ackroyd (1926)

New Quoatation

“Work did bestow dignity, status, meaning. Wasn’t that why people dreaded unemployment, why some men found retirement so traumatic?”

P.D. James, Original Sin (1994)

New Quoatation

Breaking the habit of being yourself by Dr Joe Dispenza

Joe Dispenza, D.C., studied biochemistry at Rutgers University in New Brunswick, New Jersey, and holds a Bachelor of Science degree with an emphasis in neuroscience. He received his Doctor of Chiropractic degree from Life University in Atlanta, Georgia, graduating magna cum laude. Dr. Dispenza’s postgraduate training and continuing education has been in neurology, neuroscience, brain function and chemistry, cellular biology, memory formation, aging and longevity. Joe Dispenza was featured in the award winning film, “What The Bleep Do We Know?”This lecture provides basic yet powerful information on how to co-create ones day and how to use focused concentration, repetition, and visualization (mental rehearsing) to rewire the brain. These are skills we can all harness.

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Comments:

I call it the circle of life; one part creates the next and so on! Thought creates emotion, emotion creates feelings, feelings create state of mind, state of mind create experience or doings and doings or experiences create thought and the circle continues.

Porter’s Testimonial, Healing

Porter ended up in a wheelchair after a car accident years ago and was told he would be a quadriplegic and never be able to walk again (among other things).

Porter is determined that he will walk again, and is supported by his own mental attitude, his family, friends and energy healer Jill Runnion. Already Porter now has the use of the upper part of his body and arms, so he is presently a paraplegic (not quadriplegic). Through a combination of tremendous will, openness to exploring alternative techniques and his dedication to understanding the brain, neuroscience and how he can heal his body, Porter shared this video of him standing for the first time, in August 2010. Porter is a student of Dr. Joe Dispenza, and has completed the Level 1 and Level 2 workshops ‘ Breaking the Habit of Being Yourself and has been actively applying the knowledge and techniques he has learned in his life, and is seeing tremendous results.