From Norwegian Institute of Public Health DA/5-HT interaction can be conceptualized on a system and on a neuronal level. On the neuro-anatomical level, 5-HT neurons in the raphe nuclei project to DA neurons in the VTA and substantia nigra, as well as to their targets in striatum and the PFC. The clearest evidence for the influenceContinue reading “How do dopamine and serotonin interact?”
Tag Archives: dopamine
A New Principle for Brain Controlled Hormone Secretion
The concentration of the hormone prolactin in the blood is controlled by dopamine. However, the system can be thrown off balance by certain drugs, especially antipsychotics, which can result in sexual side effects. A new study from Karolinska Institutet in rats, published in the journal Cell Reports, shows how dopamine can regulate itself and providesContinue reading “A New Principle for Brain Controlled Hormone Secretion”
Serotonin Deficiency Implicated in Rheumatoid Arthritis
Ra symptoms and pathology worse in mice missing enzyme needed for serotonin synthesis, according to report in the American Journal of Pathology. For the first time, serotonin (5-hydroxytryptamine, 5-HT) has been directly implicated in the pathophysiology of rheumatoid arthritis (RA). Although 5-HT is predominantly known as a neurotransmitter within the central nervous system, new evidenceContinue reading “Serotonin Deficiency Implicated in Rheumatoid Arthritis”
The Emergence of a New Dopamine Hypothesis of Schizophrenia
Summary: A collection of studies offers new insight into the role dopamine plays in schizophrenia. Source: Elsevier. Biological Psychiatry presents a special issue, “The Dopamine Hypothesis of Schizophrenia”, dedicated to recent advances in understanding the role of dopamine signaling in schizophrenia. The issue, organized by Anissa Abi-Dargham, MD, of Stony Brook University, New York, andContinue reading “The Emergence of a New Dopamine Hypothesis of Schizophrenia”
Toxic drugs , brain and Dopamine levels
Drugs Synapse Activity Decreases. These brain scans highlight dopamine receptors, with areas of highest density shown in red. The meth abuser has severely reduced receptor levels. Other drugs, including alcohol, cocaine, and heroin, have the same effect. Aging An overwhelming number of studies have reported age-related changes in dopaminesynthesis, binding sites, and number of receptors.Continue reading “Toxic drugs , brain and Dopamine levels”
Drugs of abuse , stress , and addiction
Drugs of abuse , stress , and addiction Neuroplasticity, the putative mechanism underlying learning and memory, is modified by drugs of abuse, alcohol and may contribute to the development of the eventual addicted state. Innovative treatments directly targeting these drug-induced changes in brain reward components and circuits may be efficacious in reducing drug use and relapse.Continue reading “Drugs of abuse , stress , and addiction”
Dopamine pathways and Parkinson
Dopamine pathways is to Parkinson and Serotonin pathway is to Alzheimer’s Dopaminergic pathways, sometimes called dopaminergic projections, are neural pathways in the brain that transmit the neurotransmitter dopamine from one region of the brain to another.[1][2] The neurons of the dopaminergic pathways have axons that run the entire length of the pathway. The neurons’ somataContinue reading “Dopamine pathways and Parkinson”
About Parkinson’s and Alzheimer’s Disease
Similarities of Parkinson’s and Alzheimer’s Disease In taking care of my senior client with Parkinson’s and Dementia, I noticed the past and present health issues: constipation, metal toxicity (skin,hair,eyes) as shown in the body, lack of iron, magnesium and potassium, excess sugar consumption, low levels of Dopamine, intestinal health issues and high levels of anxiety/stress.Continue reading “About Parkinson’s and Alzheimer’s Disease”
Taste Of Beer Triggers Release Of Dopamine, happy neurotransmitter ; Cocaine bullies dopamine; MAO affects dopamine levels
Beer lift your spirits up The taste of beer alone is enough to raise one’s spirits. The taste is linked with the release of dopamine, a neurotransmitter that controls the brain’s distribution of pleasure, according to a news study published in Neuropsychopharmacology. “This is the first human demonstration that a stimulus that is reliably associatedContinue reading “Taste Of Beer Triggers Release Of Dopamine, happy neurotransmitter ; Cocaine bullies dopamine; MAO affects dopamine levels”
Patients with Parkinson’s in the hospital: risks for OTC meds, falls, aspiration pneumonia
Some commonly prescribed drugs — including Compazine and Phenergan for nausea, and Reglan to stimulate bowel function after surgery — actually block dopamine and worsen symptoms in patients with Parkinson’s. Then they are at risk for falls and fractures and for aspiration pneumonia in the hospital. Any infection can lead to delirium, because Parkinson’s patientsContinue reading “Patients with Parkinson’s in the hospital: risks for OTC meds, falls, aspiration pneumonia”